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Nuclear Transcription Factor, X-Box Binding 1 Proteins (NFX1)

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. Additionally we are shipping Nuclear Transcription Factor, X-Box Binding 1 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NFX1 4799 Q12986
NFX1 74164 B1AY10
Rat NFX1 NFX1 313166  
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Top Nuclear Transcription Factor, X-Box Binding 1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

NFX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Nuclear Transcription Factor, X-Box Binding 1 (NFX1) Interaction Partners

Human Nuclear Transcription Factor, X-Box Binding 1 (NFX1) interaction partners

  1. Human papillomavirus 16 E6 (16E6) interacts with the cellular protein NFX1-123, and they collaboratively increase the growth and differentiation master regulator, Notch1 (show NOTCH1 Proteins).

  2. NFX1-123 and human papillomavirus 16E6 upregulated Notch 1 (show NOTCH1 Proteins) expression in keratinocytes.

  3. a mechanism for HPV16 E6 activation of the NFkappaB (show NFKB1 Proteins) pathway through NFX1-91

  4. HuD (show ELAVL4 Proteins) acts as a novel adaptor protein to recruit TAP for efficient export of ARE-containing mRNAs in neuronal cells

  5. the induction of hTERT telomerase by the HPV-16 E6/E6-AP (show ube3a Proteins) complex involves targeting of NFX1-91, a newly identified repressor of telomerase, for ubiquitination and degradation.

  6. Nrf1 (show NFE2L1 Proteins) is normally targeted to the endoplasmic reticulum membrane and endoplasmic reticulum stress may play a role in modulating Nrf1 (show NFE2L1 Proteins) function as a transcriptional activator

  7. data suggest that NFX1-123 is integral to hTERT regulation in HPV16 E6-expressing epithelial cells and that the interaction between NFX1-123 and poly(A) binding proteins is critical to hTERT activity

  8. These data demonstrate that targeted degradation of NFX1-91 by E6/E6AP (show ube3a Proteins) dissociates the mSin3A/HDAC (show HDAC3 Proteins) complex from the hTERT promoter and induces hTERT transcription.

  9. NFX1-123 is a cytoplasmic protein (show BLZF1 Proteins) that colocalizes with poly(A) binding proteins, and binds hTERT mRNA in HPV16 E6-expressing keratinocytes.

Mouse (Murine) Nuclear Transcription Factor, X-Box Binding 1 (NFX1) interaction partners

  1. Mutation E610G, quantitatively accounts for the Nxf1 (show NXF1 Proteins) modifier gene activity toward IAP (show ALPI Proteins) insertion.

  2. nuclear accumulation and modulation of unfolded protein response regulated by subunit of phosphoinositide 3-kinase

  3. nuclear translocation regulated by p85alpha and p85beta monomers of PI3K

Nuclear Transcription Factor, X-Box Binding 1 (NFX1) Protein Profile

Protein Summary

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

Gene names and symbols associated with NFX1

  • nuclear transcription factor, X-box binding 1 (NFX1)
  • nuclear transcription factor, x-box binding 1 (CpipJ_CPIJ011986)
  • nuclear transcription factor, X-box binding 1 (nfx1)
  • nuclear transcription factor, X-box binding 1 (Nfx1)
  • 1300017N15Rik protein
  • 3000003M19Rik protein
  • NFX.1 protein
  • NFX1 protein
  • NFX2 protein
  • TEG-42 protein
  • Tex42 protein

Protein level used designations for NFX1

nuclear transcription factor, X-box binding 1 , nuclear transcription factor, x-box binding 1 , transcriptional repressor NF-X1-like , nuclear transcription factor, X box-binding protein 1 , transcriptional repressor NF-X1 , m-Nfx.1 , nuclear X box binding factor 1 , testis expressed gene 42

GENE ID SPECIES
420796 Gallus gallus
465042 Pan troglodytes
6044908 Culex quinquefasciatus
100009971 Monodelphis domestica
100399247 Callithrix jacchus
100488254 Xenopus (Silurana) tropicalis
100590740 Nomascus leucogenys
4799 Homo sapiens
481581 Canis lupus familiaris
515680 Bos taurus
74164 Mus musculus
313166 Rattus norvegicus
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