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NUCB2 encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. Additionally we are shipping Nucleobindin 2 Proteins (39) and Nucleobindin 2 Kits (32) and many more products for this protein.
Showing 10 out of 136 products:
Chicken Polyclonal NUCB2 Primary Antibody for IHC, WB - ABIN2774832
Linē, Stengrēvics, Slucka, Li, Jankevics, Rees: Serological identification and expression analysis of gastric cancer-associated genes. in British journal of cancer 2002
Show all 2 references for ABIN2774832
Human Polyclonal NUCB2 Primary Antibody for IF (p), IHC (p) - ABIN700690
Jia, Li, Li, Wu, Xie, Lin: Role of nesfatin-1 in a rat model of visceral hypersensitivity. in World journal of gastroenterology : WJG 2013
Human Polyclonal NUCB2 Primary Antibody for IAC, IEM - ABIN2452060
Taniguchi, Taniura, Niinobe, Takayama, Tominaga-Yoshino, Ogura, Yoshikawa: The postmitotic growth suppressor necdin interacts with a calcium-binding protein (NEFA) in neuronal cytoplasm. in The Journal of biological chemistry 2000
It is confirmed herein that nesfatin-1 can regulate appetite in the pig and affect the gonadotropic axis of the prepubertal pig
Suggest that catecholaminergic and c-fos immunoreactive NUCB2/nesfatin-1 neurons could contribute in the anorexigenic effects of the mycotoxin deoxynivalenol.
nesfatin-1 might have an important role in regulation of food intake and pathogenesis of loss of appetite in children.
Nesfatin-1 levels were significantly lower in metabolic syndrome (MS) group compared to non-MS group
These results corroborate the suggestion of NUCB2/nesfatin-1 being relevantly involved in the regulation of mood and stress in a sex-specific way
Serum nesfatin-1 levels are significantly higher in girls with premature thelarche compared to prepubertal controls.
Circulating NUCB2/nesfatin-1 levels correlated positively with perceived anxiety, whereas no association with body mass index or eating disorder symptoms was observed.
Our results show that NUCB2 plays an important role in tumorigenesis and progression and is a potential molecular biomarker for the diagnosis and targeted therapy of ccRCC.
This investigation indicates a marked association of serum and synovial fluid nesfatin-1 concentrations with osteoarthritis disease severity.
This study shows an association of serum nesfatin-1 concentrations and the development and severity of peripheral arterial disease in type 2 diabetes mellitus patients.
Plasma IL-6 (show IL6 Antibodies) and TNF-alpha (show TNF Antibodies) did not significantly change after training, but nesfatin increased significantly only with high-intensity interval training compared with the control group.
nesfatin-1 inhibits the growth of adrenocortical H295R cells and promotes apoptosis, potentially via the involvement of Bax (show BAX Antibodies), BCL-XL (show BCL2L1 Antibodies) and BCL-2 (show BCL2 Antibodies) genes as well as ERK1/2 (show MAPK1/3 Antibodies), p38 (show CRK Antibodies) and JNK1 (show MAPK8 Antibodies)/2 signalling cascades
Polymorphism in the exon 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 and 11 of bovine NUCB2 gene was detected in 686 individuals from three Chinese cattle breeds.
Study provides evidence for direct regulation of hepatic lipid metabolism by nesfatin-1 through an AMPK (show PRKAA1 Antibodies)-dependent mechanism.
reproductive-endocrine regulation through hypothalamus-pituitary-ovary axis may contribute to nesfatin-1/NUCB2 expression in the pituitary gland.
new information on the cell specific localization of NUCB2/nesfatin-1 in the intestinal mucosa, and a novel function for nesfatin-1 in modulating intestinal CCK (show CCK Antibodies) and PYY expression and secretion
MGN3-1 cells respond differently to nutrients in secreting NUCB2/nesfatin-1 and ghrelin (show GHRL Antibodies). Similarly, acute or chronic intake of nutrients does influence NUCB2 mRNA expression and NUCB2/nesfatin-1 release in a diet specific manner.
Our data suggested that nesfatin-1 exerted its neuroprotective effect on dopaminergic cells against rotenone by ameliorating mitochondrial dysfunction and its anti-apoptotic property.
NUCB2/nesfatin-1 is co-localized with GLP-1 (show GCG Antibodies) and GIP (show GIP Antibodies) in small intestinal cells. Data support the hypothesis that nesfatin-1 is present in enteroendocrine cells and that it stimulates incretin secretion.
These results indicate that paraventricular nucleus NUCB2/nesfatin-1 is directly targeted by leptin (show LEP Antibodies), and mediates its anorexigenic effect.
influence of nesfatin-1 on lipid metabolism either in physiological or diabetic conditions
study demonstrated cytoplasmic localization of NUCB2/nesfatin-1 peptide in both human and murine chondrocytes.
pro-osteogenic activity of NUCB2(1-83)
This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. This protein binds calcium and has EF-folding domains.
, DNA-binding protein NEFA
, gastric cancer antigen Zg4
, nucleobinding 2