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NOL3 encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Additionally we are shipping Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) Proteins (15) and many more products for this protein.
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Human Polyclonal NOL3 Primary Antibody for EIA, WB - ABIN499329
Geertman, McMahon, Sabban: Cloning and characterization of cDNAs for novel proteins with glutamic acid-proline dipeptide tandem repeats. in Biochimica et biophysica acta 1996
Show all 4 references for ABIN499329
Human Polyclonal NOL3 Primary Antibody for EIA, IHC (p) - ABIN499327
Marcelli, Olimpieri, Volonterio: Domino synthesis of 1,3,5-trisubstituted hydantoins: a DFT study. in Organic & biomolecular chemistry 2011
Show all 2 references for ABIN499327
Human Polyclonal NOL3 Primary Antibody for WB - ABIN2774609
Murtaza, Wang, Feng, Alenina, Bader, Prabhakar, Li: Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy. in The Journal of biological chemistry 2008
Human Polyclonal NOL3 Primary Antibody for WB - ABIN153055
Mak, Mak, Ruvolo, Jacamo, Kornblau, Kantarjian, Andreeff, Carter: Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia. in British journal of haematology 2014
Human Polyclonal NOL3 Primary Antibody for EIA, WB - ABIN500371
Jin, El-Deiry: Overview of cell death signaling pathways. in Cancer biology & therapy 2005
Increased ARC expression is associated with liver metastasis of colorectal cancer.
RUNX3 (show RUNX3 Antibodies), miR (show MLXIP Antibodies)-185 and ARC regulate the sensitivity of gastric cancer cells to chemotherapy.
ARC is regulated via BIRC2 (show BIRC2 Antibodies)/MAP3K14 (show MAP3K14 Antibodies) signalling and its overexpression in AML (show RUNX1 Antibodies) or MSCs can function as a resistant factor to birinapant-induced leukaemia cell death.
high expression of ARC plays an important role in the pathogenesis of nasopharyngeal carcinoma and leads to X-radiation and cisplatin resistance in nasopharyngeal carcinoma.
ARC is a previously unrecognized inhibitor of apoptosis in beta-cells and that its protective effects are mediated through suppression of the ER stress response pathway.
This study utilized unbiased, genome-wide approaches to identify a NOL3 mutation that likely causes Familial cortical myoclonus.
(9)-THC for 24 h produces a dose-dependent NOP receptor down-regulation & decrease in NOP mRNA levels.
HIF-1alpha (show HIF1A Antibodies) directly bound to hypoxia-responsive element located at -419 to -414 of ARC gene, which is essential for HIF-1 (show HIF1A Antibodies)-induced expression.
Data show that ARC promotes breast carcinogenesis by driving primary tumor growth, invasion, and metastasis as well as by promoting chemoresistance in invasive cells.
ARC, previously unlinked to pulmonary hypertension, is a critical determinant of vascular remodeling in this syndrome.
Although mice lacking Men1 (show MEN1 Antibodies) developed insulinomas as expected, elimination of ARC in this context did not significantly alter tumor load. Cellular rates of proliferation and death in these tumors were also not perturbed in the absence of ARC.
interaction of ARC with TNF (show TNF Antibodies) receptor 1 Interferes with recruitment of RIP1 (show RALBP1 Antibodies), a critical mediator of TNFalpha (show TNF Antibodies)-induced regulated necrosis.
Arc deficiency in dystrophic muscle exacerbates disease pathogenesis due to a Bax (show BAX Antibodies)-mediated sensitization of mitochondria-dependent death mechanisms
On biomechanical stress induced by aortic banding, ARC-deficient mice developed accelerated cardiomyopathy, which was characterized by reduced contractile function, cardiac enlargement, and myocardial fibrosis
catalase (show CAT Antibodies), CK2 (show CSNK2A1 Antibodies), and ARC constitute an anti-hypertrophic pathway in the heart.
endogenous nociceptin (show PNOC Antibodies) differentially modulates diet preference depending on macronutrient content and homeostatic state, independently of the motivating, rewarding or orosensory properties of food, but may involve metabolic or postingestive processes.
This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene.
muscle-enriched cytoplasmic protein
, nucleolar protein 3
, nucleolar protein of 30 kDa
, apoptosis repressor with CARD