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anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) Antibodies

NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. Additionally we are shipping Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Proteins (24) and Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Kits (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPM1 4869 P06748
NPM1 25498 P13084
NPM1 18148 Q61937
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Top anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Antibodies at antibodies-online.com

Showing 10 out of 389 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Goat Un-conjugated EIA, WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of NPM1 Antibody (N-term) (ABIN389342) in T47D, A2058, A375 cell line lysates (35 µg/lane). NPM1 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of NPM1(arrow) using rabbit polyclonal NPM1 Antibody (N-term) (ABIN389342). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the NPM1 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of NPM1 (arrow) using rabbit polyclonal NPM1 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NPM1 gene (Lane 2) (Origene Technologies). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-NPM1 Antibody Titration: 1.0ug/mlPositive Control: HepG2 cell lysate Sample Type: human cornea (frozen)Blue: DAPIRed: NPM1Primary Dilution: 1:100Image Submitted By: Geraint ParfittGavin Herbert Eye Institute . 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-NPM1 Antibody Titration: 1.0ug/mlPositive Control: HepG2 cell lysate Sample Type: human cornea (frozen)Blue: DAPIRed: NPM1Primary Dilution: 1:100Image Submitted By: Geraint ParfittGavin Herbert Eye Institute . 100 μL Log in to see 2 to 3 Days
$229.00
Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-NPM1 Antibody Titration: 1.0ug/mlPositive Control: HepG2 cell lysate Sample Type: human cornea (frozen)Blue: DAPIRed: NPM1Primary Dilution: 1:100Image Submitted By: Geraint ParfittGavin Herbert Eye Institute . 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells treated with nocodazole 1ug/ml 18h, using NPM (Phospho-Thr234) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of NPM1 (arrow) using rabbit polyclonal NPM1 Antibody (C-term) (ABIN389343). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the NPM1 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185372 (0.1µg/ml) staining of Hela lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details

NPM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Antibodies

  1. Human Polyclonal NPM1 Primary Antibody for EIA, WB - ABIN453229 : Vascotto, Fantini, Romanello, Cesaratto, Deganuto, Leonardi, Radicella, Kelley, DAmbrosio, Scaloni, Quadrifoglio, Tell: APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. in Molecular and cellular biology 2009 (PubMed)
    Show all 3 references for ABIN453229

  2. Cow (Bovine) Polyclonal NPM1 Primary Antibody for IHC, WB - ABIN2778260 : Falini, Mecucci, Tiacci, Alcalay, Rosati, Pasqualucci, La Starza, Diverio, Colombo, Santucci, Bigerna, Pacini, Pucciarini, Liso, Vignetti, Fazi, Meani, Pettirossi, Saglio, Mandelli, Lo-Coco, Pelicci et al.: Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. ... in The New England journal of medicine 2005 (PubMed)
    Show all 3 references for ABIN2778260

  3. Human Polyclonal NPM1 Primary Antibody for FACS, IF - ABIN389343 : Zhang, Shi, Paddon, Hampong, Dai, Pelech: B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN389343

  4. Human Polyclonal NPM1 Primary Antibody for EIA, WB - ABIN358005 : Ma, Kantarjian, Zhang, Jilani, Sheikholeslami, Donahue, Ravandi, Estey, OBrien, Keating, Giles, Albitar: Detection of nucleophosmin gene mutations in plasma from patients with acute myeloid leukemia: clinical significance and implications. in Cancer biomarkers : section A of Disease markers 2009 (PubMed)
    Show all 2 references for ABIN358005

  5. Human Polyclonal NPM1 Primary Antibody for ELISA, WB - ABIN185372 : Grisendi, Pandolfi: NPM mutations in acute myelogenous leukemia. in The New England journal of medicine 2005 (PubMed)
    Show all 2 references for ABIN185372

  6. Human Polyclonal NPM1 Primary Antibody for ELISA, WB - ABIN1531720 : Chan, Liu, Borjigin, Busch, Rennert, Tease, Chan: Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth. in Biochemistry 1989 (PubMed)

More Antibodies against Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Interaction Partners

Human Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) interaction partners

  1. In pediatric patients with AML (show RUNX1 Antibodies) from Argentina, a favorable prognosis of AML (show RUNX1 Antibodies) with genotype NPM1-mutated/FLT3 (show FLT3 Antibodies)-ITD-negative was confirmed.

  2. This study investigated the expression level of miR-1 (show FSD1 Antibodies), miR (show MLXIP Antibodies)-486, and let-7a in 45 CN-AML (show RUNX1 Antibodies) patients well characterized for FLT3 (show FLT3 Antibodies) and/or NPM1 mutations using real-time quantitative RT-PCR and evaluated the association between candidate miRs expression and clinical features

  3. data showed that the pre-transplant level of MRD in patients with normal karyotype AML (show RUNX1 Antibodies) harboring NPM1 mutation in CR provides important prognostic information, which as an independent prognostic factor predicts transplant results

  4. Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia (show BCL11A Antibodies).

  5. In this study, a direct association was observed between NPMc(+)expression in AML (show RUNX1 Antibodies), reduced antioxidant responses, and enhanced sensitivity to an oral proteasome inhibitor that induces oxidative stress.

  6. analysis of the frequency and features of Acute myeloid leukemia (show BCL11A Antibodies) with mutated NPM1 in Indian patients

  7. Nucleophosmin Interacts with promyelocytic leukemia protein (show PML Antibodies)/retinoic acid receptor alpha (show RARA Antibodies) Only in the Resistant Cell Line.

  8. Longitudinal qPCR monitoring of nucleophosmin 1 mutations after allogeneic hematopoietic stem cell transplantation to predict AML (show RUNX1 Antibodies) relapse.

  9. results suggest that cup-like nuclei represent an important morphologic clue that can predict NPMc+ AML (show RUNX1 Antibodies) and guide toward prioritizing the further workup of AML (show RUNX1 Antibodies) patients

  10. Nucleophosmin (NPM1) integrates within the nucleolus via a multi-modal mechanism involving multivalent interactions with proteins containing arginine-rich linear motifs (R-motifs) and ribosomal RNA (rRNA).

Cow (Bovine) Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) interaction partners

  1. Results suggest that some polymorphisms in NPM1 are associated with body weight at some ages and may be used as candidates for marker-assisted selection and management in beef cattle breeding programmes.

  2. The NPM1 gene is a candidate gene for growth traits in cattle.

Mouse (Murine) Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) interaction partners

  1. The levels of B23 expression are directly regulated by EGR1 (show EGR1 Antibodies).

  2. IDH2 (show IDH2 Antibodies) and NPM1 (show GJA1 Antibodies) mutations synergize in the development and maintenance of acute myeloid leukemia (show BCL11A Antibodies) stem-like cells.

  3. Lrrc34, a novel nucleolar protein (show MCRS1 Antibodies), interacts with npm1 (show GJA1 Antibodies) and ncl (show NCL Antibodies) and has an impact on pluripotent stem cells

  4. a function of NPM1 (show GJA1 Antibodies) in the spatial organization of nucleolus-associated heterochromatin through DNA methyltransferase (show DNMT1 Antibodies) DNMT3A (show DNMT3A Antibodies)

  5. The data presented here support a novel role for NPM1 (show GJA1 Antibodies) as a multilevel modulator of the base excision repair pathway.

  6. The mechanism of G-CSF's neuroprotection may be related in part to attenuating neuronal apoptosis by NPM1 (show GJA1 Antibodies).

  7. In conclusion, we successfully established xenotransplantation model of human FLT3 (show FLT3 Antibodies)-ITD (mut (show MUT Antibodies)) /NPM1 (show GJA1 Antibodies) (-) CN-AML (show RUNX1 Antibodies) in NOD/SCID (show PRKDC Antibodies) mice.

  8. This in vivo model of Flt3 (show FLT3 Antibodies)/ITD+/NPMc+ leukemia closely recapitulates human disease and will therefore serve as a tool for the investigation of the biology of this common disease entity

  9. HOPS (show TMUB1 Antibodies) acts as a functional bridge in the interaction between NPM and p19(Arf (show CDKN2A Antibodies))

  10. NPM-Bax (show BAX Antibodies) interaction enhances mitochondrial Bax (show BAX Antibodies) accumulation, organelle injury, and cell death.

Fruit Fly (Drosophila melanogaster) Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) interaction partners

  1. NLP is essential for the positioning of centromeres during cell division in Drosophila.

Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) Antigen Profile

Protein Summary

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with NPM1

  • nucleophosmin-like (LOC100059112) antibody
  • nucleophosmin/nucleoplasmin, 1b (npm1b) antibody
  • Nucleophosmin (npm) antibody
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1) antibody
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin) (npm1) antibody
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin) (Npm1) antibody
  • nucleophosmin 1 (Npm1) antibody
  • nucleophosmin-like (LOC100525313) antibody
  • Nucleoplasmin (Nlp) antibody
  • B23 antibody
  • B23NP antibody
  • CG7917 antibody
  • Crp1 antibody
  • Dmel\\CG7917 antibody
  • dNLP antibody
  • dNLP-S antibody
  • NO38 antibody
  • Npm antibody
  • npm4 antibody
  • p22 antibody

Protein level used designations for NPM1

nucleophosmin , nucleophosmin/nucleoplasmin, 4 , Nucleophosmin , nucleolar protein NO38 , nucleophosmin/nucleoplasmin family, member 1 , NPM , nucleolar phosphoprotein B23 , nucleoplasmin , numatrin , nucleolar protein B23.1 , nucleophosmin 1 , CG7917-PA , CG7917-PB , Nlp-PA , Nlp-PB , Nucleoplasmin-like , chromatin decondensation protein 1 , nucleoplasmin-1

GENE ID SPECIES
100059112 Equus caballus
553507 Danio rerio
100195119 Salmo salar
4869 Homo sapiens
379194 Xenopus laevis
396203 Gallus gallus
25498 Rattus norvegicus
479292 Canis lupus familiaris
614028 Bos taurus
100328693 Oryctolagus cuniculus
740704 Pan troglodytes
18148 Mus musculus
100525313 Sus scrofa
43560 Drosophila melanogaster
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