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NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. Additionally we are shipping Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Proteins (24) and Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Kits (13) and many more products for this protein.
Showing 10 out of 364 products:
Human Polyclonal NPM1 Primary Antibody for EIA, WB - ABIN453229
Vascotto, Fantini, Romanello, Cesaratto, Deganuto, Leonardi, Radicella, Kelley, DAmbrosio, Scaloni, Quadrifoglio, Tell: APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. in Molecular and cellular biology 2009
Show all 3 references for ABIN453229
Cow (Bovine) Polyclonal NPM1 Primary Antibody for IHC, WB - ABIN2778260
Falini, Mecucci, Tiacci, Alcalay, Rosati, Pasqualucci, La Starza, Diverio, Colombo, Santucci, Bigerna, Pacini, Pucciarini, Liso, Vignetti, Fazi, Meani, Pettirossi, Saglio, Mandelli, Lo-Coco, Pelicci et al.: Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. ... in The New England journal of medicine 2005
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Human Polyclonal NPM1 Primary Antibody for FACS, IF - ABIN389343
Zhang, Shi, Paddon, Hampong, Dai, Pelech: B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1. in The Journal of biological chemistry 2004
Show all 2 references for ABIN389343
Human Polyclonal NPM1 Primary Antibody for EIA, WB - ABIN358005
Ma, Kantarjian, Zhang, Jilani, Sheikholeslami, Donahue, Ravandi, Estey, OBrien, Keating, Giles, Albitar: Detection of nucleophosmin gene mutations in plasma from patients with acute myeloid leukemia: clinical significance and implications. in Cancer biomarkers : section A of Disease markers 2009
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Human Polyclonal NPM1 Primary Antibody for ELISA, WB - ABIN185372
Grisendi, Pandolfi: NPM mutations in acute myelogenous leukemia. in The New England journal of medicine 2005
Show all 2 references for ABIN185372
Human Polyclonal NPM1 Primary Antibody for ELISA, WB - ABIN1531720
Chan, Liu, Borjigin, Busch, Rennert, Tease, Chan: Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth. in Biochemistry 1989
CMML with NPM1 mutation shows histopathological features of CMML, but patients appear to have a high probability for AML (show RUNX1 Antibodies) progression and may require aggressive clinical intervention, especially in patients with a high mutation burden.
demonstrated that p-NPM-Thr234/237 is critical in invasion and migration of hepatocellular carcinoma cells
NPM-RAR (show RARA Antibodies) binding to TRADD (show TRADD Antibodies) selectively inhibits caspase (show CASP3 Antibodies) activation, while allowing activation of NFkappaB (show NFKB1 Antibodies) and JNK (show MAPK8 Antibodies)
The results indicated significant differences in the integral optical density and less so in the areas of NPM+ nucleoli in leiomyosarcomas, but not in intact myometrium and leiomyomas.
NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape
This finding implicates a new role of NPM1 in conveying tumorigenic signals from the BCR-ABL (show ABL1 Antibodies) oncoprotein to ribosome biogenesis, affecting cellular growth.
The NPM1 gene did not reveal any copy number alterations in acute myeloid leukemia (show BCL11A Antibodies).
Overexpression of the cytoplasmic mutant of nucleophosmin (NPM) causes increased phosphorylation of NPM on T199.
Results show FLT3 (show FLT3 Antibodies), NPM1, and CEBPA (show CEBPA Antibodies) combination genotype confer favourable prognosis in AML (show RUNX1 Antibodies)
Designed a real-time PCR method using 3'-modified oligonucleotides technique to detect NPM1 mutations; validated its utility in clinical samples.
Results suggest that some polymorphisms in NPM1 are associated with body weight at some ages and may be used as candidates for marker-assisted selection and management in beef cattle breeding programmes.
The NPM1 gene is a candidate gene for growth traits in cattle.
The levels of B23 expression are directly regulated by EGR1 (show EGR1 Antibodies).
IDH2 (show IDH2 Antibodies) and NPM1 (show GJA1 Antibodies) mutations synergize in the development and maintenance of acute myeloid leukemia (show BCL11A Antibodies) stem-like cells.
Lrrc34, a novel nucleolar protein (show MCRS1 Antibodies), interacts with npm1 (show GJA1 Antibodies) and ncl (show NCL Antibodies) and has an impact on pluripotent stem cells
a function of NPM1 (show GJA1 Antibodies) in the spatial organization of nucleolus-associated heterochromatin through DNA methyltransferase (show DNMT1 Antibodies) DNMT3A (show DNMT3A Antibodies)
The data presented here support a novel role for NPM1 (show GJA1 Antibodies) as a multilevel modulator of the base excision repair pathway.
The mechanism of G-CSF's neuroprotection may be related in part to attenuating neuronal apoptosis by NPM1 (show GJA1 Antibodies).
In conclusion, we successfully established xenotransplantation model of human FLT3 (show FLT3 Antibodies)-ITD (mut (show MUT Antibodies)) /NPM1 (show GJA1 Antibodies) (-) CN-AML (show RUNX1 Antibodies) in NOD/SCID (show PRKDC Antibodies) mice.
This in vivo model of Flt3 (show FLT3 Antibodies)/ITD+/NPMc+ leukemia closely recapitulates human disease and will therefore serve as a tool for the investigation of the biology of this common disease entity
HOPS (show TMUB1 Antibodies) acts as a functional bridge in the interaction between NPM and p19(Arf (show CDKN2A Antibodies))
NPM-Bax (show BAX Antibodies) interaction enhances mitochondrial Bax (show BAX Antibodies) accumulation, organelle injury, and cell death.
NLP is essential for the positioning of centromeres during cell division in Drosophila.
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
, nucleophosmin/nucleoplasmin, 4
, nucleolar protein NO38
, nucleophosmin/nucleoplasmin family, member 1
, nucleolar phosphoprotein B23
, nucleolar protein B23.1
, nucleophosmin 1
, chromatin decondensation protein 1