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NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. Additionally we are shipping Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Proteins (24) and Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) Kits (13) and many more products for this protein.
Showing 10 out of 367 products:
Human Polyclonal NPM1 Primary Antibody for EIA, WB - ABIN453229
Vascotto, Fantini, Romanello, Cesaratto, Deganuto, Leonardi, Radicella, Kelley, DAmbrosio, Scaloni, Quadrifoglio, Tell: APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. in Molecular and cellular biology 2009
Show all 3 references for ABIN453229
Cow (Bovine) Polyclonal NPM1 Primary Antibody for IHC, WB - ABIN2778260
Falini, Mecucci, Tiacci, Alcalay, Rosati, Pasqualucci, La Starza, Diverio, Colombo, Santucci, Bigerna, Pacini, Pucciarini, Liso, Vignetti, Fazi, Meani, Pettirossi, Saglio, Mandelli, Lo-Coco, Pelicci et al.: Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. ... in The New England journal of medicine 2005
Show all 3 references for ABIN2778260
Human Polyclonal NPM1 Primary Antibody for FACS, IF - ABIN389343
Zhang, Shi, Paddon, Hampong, Dai, Pelech: B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1. in The Journal of biological chemistry 2004
Show all 2 references for ABIN389343
Human Polyclonal NPM1 Primary Antibody for EIA, WB - ABIN358005
Ma, Kantarjian, Zhang, Jilani, Sheikholeslami, Donahue, Ravandi, Estey, OBrien, Keating, Giles, Albitar: Detection of nucleophosmin gene mutations in plasma from patients with acute myeloid leukemia: clinical significance and implications. in Cancer biomarkers : section A of Disease markers 2009
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Human Polyclonal NPM1 Primary Antibody for ELISA, WB - ABIN185372
Grisendi, Pandolfi: NPM mutations in acute myelogenous leukemia. in The New England journal of medicine 2005
Show all 2 references for ABIN185372
Human Polyclonal NPM1 Primary Antibody for ELISA, WB - ABIN1531720
Chan, Liu, Borjigin, Busch, Rennert, Tease, Chan: Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth. in Biochemistry 1989
Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia (show BCL11A Antibodies).
In this study, a direct association was observed between NPMc(+)expression in AML (show RUNX1 Antibodies), reduced antioxidant responses, and enhanced sensitivity to an oral proteasome inhibitor that induces oxidative stress.
analysis of the frequency and features of Acute myeloid leukemia (show BCL11A Antibodies) with mutated NPM1 in Indian patients
Nucleophosmin Interacts with promyelocytic leukemia protein (show PML Antibodies)/retinoic acid receptor alpha (show RARA Antibodies) Only in the Resistant Cell Line.
Longitudinal qPCR monitoring of nucleophosmin 1 mutations after allogeneic hematopoietic stem cell transplantation to predict AML (show RUNX1 Antibodies) relapse.
results suggest that cup-like nuclei represent an important morphologic clue that can predict NPMc+ AML (show RUNX1 Antibodies) and guide toward prioritizing the further workup of AML (show RUNX1 Antibodies) patients
Nucleophosmin (NPM1) integrates within the nucleolus via a multi-modal mechanism involving multivalent interactions with proteins containing arginine-rich linear motifs (R-motifs) and ribosomal RNA (rRNA).
Data show that apoptotic cell death by esculetin was associated with inhibition of the EGFR (show EGFR Antibodies)/PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway and the decreased expression of nucleophosmin (NPM).
NPM1 mutations contribute to the invasive potential of acute myeloid leukemia (show BCL11A Antibodies) cells through MMPs up-regulation via Ras/ERK MAPK (show MAPK1 Antibodies) signaling pathway activation.
NPM1 Mutation Detection in Acute Myeloid Leukemia (show BCL11A Antibodies)
Results suggest that some polymorphisms in NPM1 are associated with body weight at some ages and may be used as candidates for marker-assisted selection and management in beef cattle breeding programmes.
The NPM1 gene is a candidate gene for growth traits in cattle.
The levels of B23 expression are directly regulated by EGR1 (show EGR1 Antibodies).
IDH2 (show IDH2 Antibodies) and NPM1 (show GJA1 Antibodies) mutations synergize in the development and maintenance of acute myeloid leukemia (show BCL11A Antibodies) stem-like cells.
Lrrc34, a novel nucleolar protein (show MCRS1 Antibodies), interacts with npm1 (show GJA1 Antibodies) and ncl (show NCL Antibodies) and has an impact on pluripotent stem cells
a function of NPM1 (show GJA1 Antibodies) in the spatial organization of nucleolus-associated heterochromatin through DNA methyltransferase (show DNMT1 Antibodies) DNMT3A (show DNMT3A Antibodies)
The data presented here support a novel role for NPM1 (show GJA1 Antibodies) as a multilevel modulator of the base excision repair pathway.
The mechanism of G-CSF's neuroprotection may be related in part to attenuating neuronal apoptosis by NPM1 (show GJA1 Antibodies).
In conclusion, we successfully established xenotransplantation model of human FLT3 (show FLT3 Antibodies)-ITD (mut (show MUT Antibodies)) /NPM1 (show GJA1 Antibodies) (-) CN-AML (show RUNX1 Antibodies) in NOD/SCID (show PRKDC Antibodies) mice.
This in vivo model of Flt3 (show FLT3 Antibodies)/ITD+/NPMc+ leukemia closely recapitulates human disease and will therefore serve as a tool for the investigation of the biology of this common disease entity
HOPS (show TMUB1 Antibodies) acts as a functional bridge in the interaction between NPM and p19(Arf (show CDKN2A Antibodies))
NPM-Bax (show BAX Antibodies) interaction enhances mitochondrial Bax (show BAX Antibodies) accumulation, organelle injury, and cell death.
NLP is essential for the positioning of centromeres during cell division in Drosophila.
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
, nucleophosmin/nucleoplasmin, 4
, nucleolar protein NO38
, nucleophosmin/nucleoplasmin family, member 1
, nucleolar phosphoprotein B23
, nucleolar protein B23.1
, nucleophosmin 1
, chromatin decondensation protein 1