NPM1 antibody (C-Term)
Quick Overview for NPM1 antibody (C-Term) (ABIN389343)
Target
See all NPM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 198-226, C-Term
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This NPM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human NPM1.
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Isotype
- Ig Fraction
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Application Notes
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
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Alternative Name
- NPM1
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Background
- NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
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Molecular Weight
- 32575
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Gene ID
- 4869
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NCBI Accession
- NP_001032827, NP_002511, NP_954654
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UniProt
- P06748
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Target
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