NPM1 antibody (AA 81-294)

Catalog No. ABIN165442

This Mouse Monoclonal antibody specifically detects NPM1 in WB, IHC, IF, ELISA, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for NPM1 antibody (AA 81-294) (ABIN165442)

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NPM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 5E3

Product Details anti-NPM1 Antibody

Binding Specificity: AA 81-294

Purpose: Human NPM1 antibody

Purification: Purified

Immunogen: Recombinant human NPM (81-294aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Application Notes: Recommended dilution 1:1000(W.B), Recommended dilution 1:100(IHC)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for NPM1

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Alternative Name: NPM1

Background: Nucleophosmin (NPM, also known as B23, NO38, or numatrin) is a nucleolar phosphoprotein that binds the tumor suppressors p53 and p19Arf and is thought to be indispensable for ribogenesis, cell proliferation, and survival after DNA damage. Nucleophosmin is upregulated in many cancer cells.

NCBI Accession: NP_002511

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly