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Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Proteins (NACC1)

The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Additionally we are shipping Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Antibodies (79) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NACC1 112939 Q96RE7
NACC1 66830 Q7TSZ8
NACC1 171454 O35260
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Top Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,461.33
Details

NACC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Rat (Rattus)

More Proteins for Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) Interaction Partners

Human Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) interaction partners

  1. Mutations in SCN1A (show SCN1A Proteins), the gene that encodes the alpha subunit (show POLG Proteins) of voltage-gated sodium channel Nav1.1 (show SCN1A Proteins), can cause epilepsies.

  2. Retrospective study to survey the efficacy of antiepileptic drugs in Dravet syndrome with different SCN1A (show SCN1A Proteins) genotypes

  3. No causative variants were identified in any of non-DS epileptic patients in our cohort, suggesting a minor, but not irrelevant role for SCN1A (show SCN1A Proteins) in patients with other types of childhood epilepsy.

  4. Mutations in SCN1A (show SCN1A Proteins) and SCN2A (show SCN2A Proteins) are a predisposing factor of acute encephalopathy with biphasic seizures and late reduced diffusion

  5. Evaluation of Presumably Disease Causing SCN1A (show SCN1A Proteins) Variants in a Cohort of Common Epilepsy Syndromes.

  6. The SCN1A (show SCN1A Proteins) IVS5-91G>A SNP is associated with susceptibility to epilepsy. SNPs in EPHX1 (show EPHX1 Proteins) gene are influencing CBZ metabolism and disposition

  7. Human Nav1.6 (show SCN8A Proteins) channels generate larger resurgent currents than human Nav1.1 (show SCN1A Proteins) channels, but the SCN4B (show SCN4B Proteins)-derived Navbeta4 (show SCN4B Proteins) peptide does not protect either isoform from use-dependent reduction.

  8. NAC1 has potential as a marker for distinguishing OED from CIS (show CISH Proteins)/OSCC

  9. We report the association of two novel homozygous missense mutations of the SCN1A (show SCN1A Proteins) gene in four children with infantile epilepsies from two consanguineous pedigrees

  10. This study provide the evidence SCN1A (show SCN1A Proteins) mutation releate to Autism Spectrum Disorder.

Mouse (Murine) Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) interaction partners

  1. The interaction of Nac1 with Miz1 (show PIAS2 Proteins) may thus be relevant to its mechanism of tumourigenesis in ovarian cancer.

  2. NAC1 participates in the motility and differentiation of developing chondrocytes and cartilaginous tissues, and its expression is necessary to maintain normal axial patterning of murine skeleton.

  3. The mouse Nac1 gene consist of six exons, with exon 2 containing an alternative splice donor, providing a molecular explanation of the splice variants observed in mouse and rat.

  4. these data indicate involvement of NAC1 in the acute behavioral and neurochemical responses to psychomotor stimulants

  5. Nanog (show NANOG Proteins) interacts with Nac1 through WNAAP to regulate the cell cycle of stem cells via the ERas/phosphatidylinositol 3-kinase/Akt (show AKT1 Proteins) pathway, but not pluripotency

Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) Protein Profile

Protein Summary

The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.

Gene names and symbols associated with NACC1

  • nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (NACC1)
  • nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (Nacc1)
  • sodium channel, voltage-gated, type I, alpha subunit (SCN1A)
  • 2010001H03Rik protein
  • 4930511N13Rik protein
  • BEND8 protein
  • Btbd14b protein
  • BTBD30 protein
  • EIEE6 protein
  • FEB3 protein
  • FEB3A protein
  • FHM3 protein
  • GEFSP2 protein
  • HBSCI protein
  • Nac-1 protein
  • Nac1 protein
  • NACC1 protein
  • Nav1.1 protein
  • SCN1 protein
  • SMEI protein

Protein level used designations for NACC1

BEN domain containing 8 , BTB/POZ domain-containing protein 14B , nucleus accumbens-associated protein 1 , transcriptional repressor NAC1 , nucleus accumbens associated 1, BEN and BTB (POZ) domain containing , BTB (POZ) domain containing 14B , NAC-1 , nucleus accumbens-1 , sodium channel protein type 1 subunit alpha , sodium channel protein type I subunit alpha , sodium channel protein, brain I alpha subunit , sodium channel voltage gated type 1 alpha subunit , sodium channel, voltage-gated, type I, alpha polypeptide , voltage-gated sodium channel subunit alpha Nav1.1

GENE ID SPECIES
112939 Homo sapiens
484918 Canis lupus familiaris
525378 Bos taurus
66830 Mus musculus
171454 Rattus norvegicus
6323 Homo sapiens
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