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NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 Proteins (NDEL1)

NDEL1 encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Additionally we are shipping NDEL1 Antibodies (109) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NDEL1 83431 Q9ERR1
NDEL1 81565 Q9GZM8
Rat NDEL1 NDEL1 170845 Q78PB6
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Top NDEL1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,937.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,938.83
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,942.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$510.36
Details

NDEL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1) Interaction Partners

Mouse (Murine) NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1) interaction partners

  1. NDEL1 facilitates the reversal of somatodendritic traansport in the proximal axon.

  2. study provided comprehensive documentation of the expression patterns of Nde1 and Ndel1 in cultured cells as well as in mouse and human brains, and also highlighting that dosage effects of these two proteins might contribute to some cases of mental disorder

  3. Results suggest that NDEL1 might interact with DISC1 (show DISC1 Proteins) to activate ERK (show EPHB2 Proteins) signaling and function as a potential protective factor during the spontaneous seizure period after pilocarpine-induced status epilepticus

  4. Results show that LIS1 (show PAFAH1B1 Proteins) acts via the LIS1 (show PAFAH1B1 Proteins)-NDEL1-dynein complex to regulate astral microtubule MT plus-ends dynamics and establish proper contacts of MTs (show NEU2 Proteins) with the cell cortex to ensure precise cell division.

  5. Nuclear distribution element-like 1 (Ndel1 or Nudel) was firstly described as a regulator of the cytoskeleton in microtubule and intermediate filament dynamics and microtubule-based transport.

  6. Expressing a mutant Ndel1 lacking key phosphorylation sites shuts down organelle transport completely in axons.

  7. palmitoylated Ndel1 reduced cytoplasmic dynein (show DYNC1H1 Proteins) activity as judged by Golgi distribution, VSVG and short microtubule trafficking, transport of endogenous Ndel1 and LIS1 (show PAFAH1B1 Proteins) from neurite tips to the cell body and neuronal migration

  8. Lis1 (show PAFAH1B1 Proteins) and Ndel1 are essential for normal cortical neuronal migration, neurite outgrowth, and function of the microtubule organizing center in a dose-dependent manner.

  9. The predicted peptide product resulting from the Scottish translocation removes the interaction domain for Nudel. Nudel is able to act as a bridge between DISC1 (show DISC1 Proteins) and Lis1 (show PAFAH1B1 Proteins) to allow formation of a trimolecular complex.

  10. NUDEL is important for NF assembly, transport and neuronal integrity. NUDEL facilitates the polymerization of NFs through a direct interaction with the NF light subunit (NF-L (show NEFL Proteins)).

Human NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1) interaction partners

  1. This study observed a significantly increased myelin basic protein (MBP (show MBP Proteins)) and nuclear distribution protein nudE-like 1 (NDEL1) mRNA levels in FEP patients compared with controls.

  2. study provided comprehensive documentation of the expression patterns of Nde1 and Ndel1 in cultured cells as well as in mouse and human brains, and also highlighting that dosage effects of these two proteins might contribute to some cases of mental disorder

  3. The Plasma Ndel1 enzyme activity is reduced in patients with schizophrenia.

  4. Short (DISC)1 splice variants show reduced or no binding to nudE nuclear distribution E homolog (NDEL)1 and phosphodiesterase (PDE)4B proteins, but fully interact with FEZ1 and glycogen synthase kinase 3 (GSK3)beta.

  5. Nudel markedly promotes the HSPC300 (show BRK1 Proteins)-WAVE2 (show WASF2 Proteins) interaction.

  6. analysis of mixed NDE1-NDEL1 complexes demonstrates that NDE1 and NDEL1 can interact directly.

  7. Cytosolic mfGbeta is recruited to dynein by Nudel and transported to the centrosome for rapid sequestration and degradation.

  8. Studies indicate that binding of dynactin (show DCTN1 Proteins), LIS1 (show PAFAH1B1 Proteins) and NudEL regulate cytoplasmic dynein (show DYNC1H1 Proteins) motor activity.

  9. DISC1 (show DISC1 Proteins) forms octamers via dimers as building blocks. S704C forms higher-order oligomers, without affecting its affinity with NDEL1

  10. Nuclear distribution element-like 1 (Ndel1 or Nudel) was firstly described as a regulator of the cytoskeleton in microtubule and intermediate filament dynamics and microtubule-based transport.

NDEL1 Protein Profile

Protein Summary

This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome X.

Gene names and symbols associated with NDEL1

  • nudE nuclear distribution E homolog (A. nidulans)-like 1 (NDEL1)
  • nuclear distribution gene E-like homolog 1 (A. nidulans) (Ndel1)
  • nudE neurodevelopment protein 1-like 1 (NDEL1)
  • nudE nuclear distribution gene E homolog (A. nidulans)-like 1 (NDEL1)
  • nudE nuclear distribution gene E homolog (A. nidulans)-like 1 (Ndel1)
  • 2600006O07Rik protein
  • EOPA protein
  • MITAP1 protein
  • mNudel protein
  • NDE1L1 protein
  • NDE2 protein
  • NUDE2 protein
  • Nudel protein

Protein level used designations for NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1 , mNudE-L , nuclear disribution gene E like , nuclear distribution protein nudE-like 1 , protein Nudel , endooligopeptidase A , mitosin-associated protein 1 , mitosin-associated protein MITAP1 , nudE nuclear distribution E homolog-like 1 , nudE nuclear distribution gene E homolog-like 1 , nudE nuclear distribution gene E homolog like 1 , endooligopeptidase A protein , LIS1-interacting protein NUDEL , LIS1-interacting protein NUDEL; endooligopeptidase A , nuclear distribution gene E-like homolog 1

GENE ID SPECIES
100062671 Equus caballus
83431 Mus musculus
81565 Homo sapiens
489495 Canis lupus familiaris
100511592 Sus scrofa
417317 Gallus gallus
100008657 Oryctolagus cuniculus
510769 Bos taurus
170845 Rattus norvegicus
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