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Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 16 Proteins (NUDT16)

RNA-decapping enzyme that binds specifically to U8 snoRNA. Additionally we are shipping NUDT16 Antibodies (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat NUDT16 NUDT16 363129  
NUDT16 131870 Q96DE0
NUDT16 75686 Q6P3D0
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Top NUDT16 Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,469.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,469.50
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,522.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NUDT16 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced NUDT16 Proteins

  1. Human NUDT16 Protein expressed in Escherichia coli (E. coli) - ABIN667321 : Ghosh, Peterson, Tomasevic, Peculis: Xenopus U8 snoRNA binding protein is a conserved nuclear decapping enzyme. in Molecular cell 2004 (PubMed)
    Show all 2 references for ABIN667321

More Proteins for Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 16 (NUDT16) Interaction Partners

Human Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 16 (NUDT16) interaction partners

  1. This study details structural and regulatory mechanisms explaining how substrates are selected for hydrolysis by human NUDT16.

  2. The RNA decapping enzyme (show DCP1A Proteins) NUDT16 selectively degrades 5'-TOP mRNAs during Rift Valley fever virus infection and this decay is triggered in response to mTOR (show FRAP1 Proteins) attenuation via the translational repressor 4EBP1 (show EIF4EBP1 Proteins)/2 axis.

  3. hNUDT16 can also actively cleave the mGDP cap from mRNAs in the presence of Mg(2 (show MUC7 Proteins))(+) or Mn(2)(+).

  4. Like Dcp2 (show DCP2 Proteins), Nudt16 also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis.

  5. NUDT16 is a (deoxy)inosine diphosphatase that may function mainly in the nucleus to protect cells from deleterious effects of (d)ITP (show ITPA Proteins).

  6. X29/H29K may be the nuclear counterparts of the cytoplasmic decapping machinery, localized in specialized bodies involved in RNA decay

  7. Recombinant NUDT16, a decapping enzyme (show DCP1A Proteins), has been crystallized. NUDT16 plays a pivotal role in U8 snoRNA stability.

Mouse (Murine) Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 16 (NUDT16) interaction partners

  1. binding interaction between syndesmos (show NUDT16L1 Proteins) and syn4 (show STX4 Proteins)(cyto) was characterized as a low-affinity interaction (Kd = 62 muM) by surface plasmon resonance and nuclear magnetic resonance

  2. Like Dcp2 (show DCP2 Proteins), Nudt16 also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis.

Xenopus laevis Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 16 (NUDT16) interaction partners

  1. Structures of X29 with GTP (show AK3 Proteins) or m7GpppA show a different mode of ligand binding from that of other cap binding proteins and suggest a possible three- or four-metal Nudix reaction mechanism.

  2. X29/H29K may be the nuclear counterparts of the cytoplasmic decapping machinery, localized in specialized bodies involved in RNA decay

NUDT16 Protein Profile

Protein Summary

RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro) (By similarity).

Gene names and symbols associated with NUDT16

  • nudix (nucleoside diphosphate linked moiety X)-type motif 16 (Nudt16)
  • nudix (nucleoside diphosphate linked moiety X)-type motif 16 (NUDT16)
  • nudix (nucleoside diphosphate linked moiety X)-type motif 16 (nudt16)
  • 2310041H06Rik protein
  • 2810047L04Rik protein
  • 2900006H04Rik protein
  • AI851783 protein
  • RGD1311387 protein
  • x29 protein

Protein level used designations for NUDT16

U8 snoRNA-decapping enzyme , IDP phosphatase , IDPase , U8 snoRNA-binding protein H29K , inosine diphosphate phosphatase , m7GpppN-mRNA hydrolase , nucleoside diphosphate-linked moiety X motif 16 , nudix motif 16 , nudix-type motif 16 , U8 snoRNA-binding protein X29

GENE ID SPECIES
363129 Rattus norvegicus
131870 Homo sapiens
75686 Mus musculus
512320 Bos taurus
654329 Ovis aries
414677 Xenopus laevis
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