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OTU Domain Containing 7B Proteins (OTUD7B)

Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Additionally we are shipping OTUD7B Antibodies (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OTUD7B 56957 Q6GQQ9
OTUD7B 229603  
Rat OTUD7B OTUD7B 310677  
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Top OTUD7B Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 5 to 8 Days
$392.70
Details
HOST_Sf-21 Cells Human His tag   50 μg Log in to see 5 to 8 Days
$523.95
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

OTUD7B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

More Proteins for OTU Domain Containing 7B (OTUD7B) Interaction Partners

Human OTU Domain Containing 7B (OTUD7B) interaction partners

  1. these data reveal a novel mechanism for the regulation of the expression of HIF2a (show EPAS1 Proteins), demonstrating that the HIF2a (show EPAS1 Proteins) promoter is regulated by E2F1 (show E2F1 Proteins) directly and that Cezanne regulates HIF2a (show EPAS1 Proteins) expression through control of E2F1 (show E2F1 Proteins) levels

  2. Taken together, these results suggest that hepatitis C virus NS5A protein interacts with OTUD7B, thereby modulating its deubiquitinase activity.

  3. Cezanne has a pivotal role in tumor progression and prognosis, and may act as a potential prognostic biomarker for survival in hepatocellular carcinoma patients.

  4. data suggest that Cezanne is essential for HIF-1alpha (show HIF1A Proteins) protein stability and that loss of Cezanne stimulates HIF-1alpha (show HIF1A Proteins) degradation via proteasome-independent routes, possibly through chaperone-mediated autophagy.

  5. Genome wide association study shows evidence of association between mammographic density and SNPs in high linkage disequilibrium with rs11205277, rs11205303 in gene MTMR11 (show MTMR11 Proteins) and rs67807996 in gene OTUD7B.

  6. Inflammatory responses to ischemia are controlled by a balance between TRAF6 ubiquitination and deubiquitination, and Cezanne is a key regulator of this process.

  7. identified a deubiquitinating enzyme, Cezanne-1, that opposes receptor degradation and enhances EGFR (show EGFR Proteins) signaling

  8. There is an excessive inflammatory response but insufficient up-regulation of A20 (show TNFAIP3 Proteins) expression in inflammatory bowel disease patients.

  9. DJ-1 (show PARK7 Proteins) enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB (show NFKB1 Proteins).

  10. Cezanne is identified as the first deubiquitinase with Lys11-linkage preference.

Mouse (Murine) OTU Domain Containing 7B (OTUD7B) interaction partners

  1. These findings establish Otud7b as a positive regulator of T cell receptor-proximal signaling and T cell activation, highlighting the importance of deubiquitination in regulating Zap70 (show ZAP70 Proteins) function.

  2. Inflammatory responses to ischemia are controlled by a balance between ubiquitination and deubiquitination, and Cezanne is a key regulator of this process.

  3. findings establish OTUD7B as a crucial regulator of signal-induced non-canonical NF-kappaB (show NFKB1 Proteins) activation and indicate a mechanism of immune regulation that involves OTUD7B-mediated deubiquitination and stabilization of TRAF3 (show TRAF3 Proteins)

  4. DJ-1 (show PARK7 Proteins) enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB (show NFKB1 Proteins).

OTUD7B Protein Profile

Protein Summary

Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.

Gene names and symbols associated with OTUD7B

  • OTU domain containing 7B (OTUD7B)
  • OTU domain containing 7B (otud7b)
  • OTU domain containing 7B (Otud7b)
  • 2900060B22Rik protein
  • 4930463P07Rik protein
  • AI462125 protein
  • CEZANNE protein
  • OTUD7B protein
  • RGD1308111 protein
  • Trabid2 protein
  • Za20d1 protein
  • zgc:152772 protein

Protein level used designations for OTUD7B

OTU domain containing 7B , zinc finger protein Cezanne , OTU domain-containing protein 7B , zinc finger, A20 domain containing 1 , cellular zinc finger anti-NF-kappa-B protein , cellular zinc finger anti-NF-kappaB Cezanne , zinc finger A20 domain-containing protein 1 , TRAF binding domain containing 2

GENE ID SPECIES
705774 Macaca mulatta
777637 Danio rerio
779455 Xenopus (Silurana) tropicalis
749087 Pan troglodytes
426041 Gallus gallus
100014166 Monodelphis domestica
100054396 Equus caballus
100446150 Pongo abelii
100464376 Ailuropoda melanoleuca
100551488 Meleagris gallopavo
100597721 Nomascus leucogenys
56957 Homo sapiens
229603 Mus musculus
483178 Canis lupus familiaris
525579 Bos taurus
310677 Rattus norvegicus
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