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OLIG2 encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. Additionally we are shipping OLIG2 Proteins (6) and OLIG2 Kits (5) and many more products for this protein.
Showing 10 out of 121 products:
Human Polyclonal OLIG2 Primary Antibody for ICC, IF - ABIN447418
Kolenda-Roberts, Harris, Singletary, Hardisty: Immunohistochemical characterization of spontaneous and acrylonitrile-induced brain tumors in the rat. in Toxicologic pathology 2012
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Human Monoclonal OLIG2 Primary Antibody for ICC, IHC - ABIN969331
Bonnet-Dupeyron, Combes, Boespflug-Tanguy, Vaurs-Barrière: Absence of OLIG2 mutations in patients presenting with a severe Pelizaeus-Merzbacher-like leukodystrophy associated with motor neuron dysfunction. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008
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Human Polyclonal OLIG2 Primary Antibody for IHC, IHC (fro) - ABIN447523
Nijland, Michailidou, Witte, Mizee, van der Pol, van Het Hof, Reijerkerk, Pellerin, van der Valk, de Vries, van Horssen: Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions. in Glia 2014
Human Monoclonal OLIG2 Primary Antibody for IF, IHC (p) - ABIN523613
Libard, Popova, Amini, Kärjä, Pietiläinen, Hämäläinen, Sundström, Hesselager, Bergqvist, Ekman, Zetterling, Smits, Nilsson, Pfeifer, de Ståhl, Enblad, Ponten, Alafuzoff: Human cytomegalovirus tegument protein pp65 is detected in all intra- and extra-axial brain tumours independent of the tumour type or grade. in PLoS ONE 2014
Dog (Canine) Polyclonal OLIG2 Primary Antibody for IHC, WB - ABIN2777314
Mitkus, Hyde, Vakkalanka, Kolachana, Weinberger, Kleinman, Lipska: Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia. in Schizophrenia research 2007
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Dog (Canine) Polyclonal OLIG2 Primary Antibody for IHC, WB - ABIN2777565
Cowen, Green: The Kallmann's syndrome variant (KSV) model of the schizophrenias. in Schizophrenia research 1993
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Dog (Canine) Polyclonal OLIG2 Primary Antibody for IHC, WB - ABIN2777566
Sun, Hafler, Kaing, Kitada, Ligon, Widlund, Yuk, Stiles, Rowitch: Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. in Developmental biology 2006
Olig2 was expressed in cord blood eosinophils on d 24, when cord blood eosinophils are considered fully differentiated, but no earlier. It was also expressed in human peripheral-blood eosinophils but not neutrophils, monocytes, lymphocytes, or cord blood mast cells. Many genes, including eosinophil surface molecules, were up-regulated along with OLIG2. OLIG2 shRNA or siRNA downregulated SIGLEC-8 (show SIGLEC8 Antibodies) mRNA and protein.
Data indicate that transcription factors Sox10 (show SOX10 Antibodies) and Olig2 play key roles in oligodendrocytes (OLs) specification.
Olig2 expressions were successfully detected in 12 (15.58%) of 77 SVZ type II Glioblastomas (GBs (show GNB5 Antibodies)) and 16 (21.3%) of 75 SVZ type III GBs (show GNB5 Antibodies).
Olig2 was positive in 5 out of 44 ependymomas (11%) and 50 out of 54 (93%) non-ependymal tumors
The present study is the first to verify the associations of SNPs rs762178, rs1059004, and rs9653711 of the OLIG2 gene with OCD in a Chinese Han population. Thus, OLIG2 might serve as a potential target for OCD treatment
The results demonstrate that the expression of Olig2 in dental pulp stem cells reduces the expression of stem cell markers and induces the development of oligodendrocyte progenitors.
High Olig2 expression is associated with oligodendrogliomas.
OLIG2 is the most specific GSC (show GSC Antibodies) marker.
Our study suggests that CGT (show UGT8 Antibodies) expression is controlled by balanced expression of the negative modulator OLIG2 and positive regulator Nkx2.2 (show Nkx2-2 Antibodies), providing new insights into how expression of GalCer is tightly regulated in cell-type- and stage-specific manners.
Authors investigated the role of Pten (show PTEN Antibodies) in these two critical cellular compartments in adult and developing brains using methods for activation or suppression of PI3K (show PIK3CA Antibodies) signaling in glial and neuronal progenitors expressing Olig2.
these data raise the possibility that cells expressing olig2 are intermediate targets that help guide facial motor neuron migration.
Study detected at least five different classes of olig2-positive cells in the telencephalon of the adult zebrafish.
By cooperating with Shh (show SHH Antibodies), FGF-receptor (show FGFR2 Antibodies) signalling controls the expression of olig2, a patterning gene essential for the specification of somatic motoneurons and oligodendrocytes.
Loss of olig2 function prevents primary motor neuron and oligodendrocyte development, whereas olig2 overexpression promotes formation of excess primary motor neurons and oligodendrocytes.
Olig2 is required for repression of iro3 (show IRX3 Antibodies) expression in the progenitor domain of ventral spinal cord
data indicate that Hedgehog (show SHH Antibodies) & Wnt (show WNT2 Antibodies) work in opposition across the dorsoventral axis of the cerebellum to regulate formation of olig2(+) neurons; we propose that Hedgehog (show SHH Antibodies) limits the range of Wnt (show WNT2 Antibodies) signaling, which is necessary for olig2(+) neuron development
commitment of basal diencephalic DA neurons is regulated by the combined action of the neural protein Olig2 and its downstream neuronal specific effector Sim1
the dynamic interplay between HMGNs and H1 in chromatin epigenetically regulates the expression of OLIG1 (show OLIG1 Antibodies)&2, thereby affecting oligodendrocyte development and myelination, and mouse behavior.
Olig2 was significantly upregulated and transcriptionally targeted the Gpr17 (show GPR17 Antibodies) locus
Brg1 (show SMARCA4 Antibodies) represses Olig2 expression and the specification of oligodendrocyte progenitors, but is required for OPC differentiation and oligodendrocyte maturation
Data show that oligodendrocyte transcription factor 2 (Olig2) deletion causes platelet-derived growth factor receptor (PDGFR (show PDGFRB Antibodies)) downregulation and reciprocal epidermal growth factor receptor (EGFR (show EGFR Antibodies)) upregulation.
This study suggests that Olig2 misexpression in neural stem cells elicits neurogenesis defects and neuronal cell death, which may contribute to developmental disorders including Down syndrome
OLIG2 is a multifunctional regulator of neural stem cell self-renewal
Olig2 expression is localized to the cochleovestibular ganglia from E12.5 through E14.5
Olig2 overexpression accelerates the differentiation of mouse embryonic stem cells into oligodendrocyte progenitor cells in vitro.
This study demonstrated that that OLIG2 overexpression in oligodendrocyte progenitor cells might be a possible therapeutic mechanism for enhancing myelin repair.
Results from expression pattern suggests that Olig2 may have an important role in the early stage of Purkinje cell development.
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14\;21)(q11.2\;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
oligodendrocyte transcription factor 4
, oligodendrocyte transcription factor 3
, oligodendrocyte lineage transcription factor 2
, basic domain, helix-loop-helix protein, class B, 1
, class B basic helix-loop-helix protein 1
, class E basic helix-loop-helix protein 19
, human protein kinase C-binding protein RACK17
, oligodendrocyte transcription factor 2
, oligodendrocyte-specific bHLH transcription factor 2
, protein kinase C-binding protein 2
, bHLH transcription factor Olig2