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anti-Organic Solute Transporter beta (OSTBETA) Antibodies

Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Additionally we are shipping Organic Solute Transporter beta Proteins (5) and Organic Solute Transporter beta Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OSTBETA 300790  
OSTBETA 123264 Q86UW2
OSTBETA 330962 Q80WK2
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Top anti-Organic Solute Transporter beta Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Alexa Fluor 350 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 594 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Cy3 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy5 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy7 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details

OSTBETA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,


, , , , , , , , , , , ,
Human ,


, , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , , ,

More Antibodies against Organic Solute Transporter beta Interaction Partners

Human Organic Solute Transporter beta (OSTBETA) interaction partners

  1. Hepatic OSTalpha (show OSTALPHA Antibodies)-OSTbeta expression is induced by hypoxia.

  2. OSTbeta is a target of RARalpha (show RARA Antibodies)-mediated (by binding to DR5 (show TNFRSF10B Antibodies) response element) gene regulation pathways

  3. Ostbeta is required for both proper trafficking of Ostalpha (show OSTALPHA Antibodies) and formation of the functional transport unit, and identify specific residues of Ostbeta critical for these processes.

  4. The present report summarizes the evidence for a pleiotropic role of Ostalpha (show OSTALPHA Antibodies)-Ostbeta in different tissues.

  5. OSTbeta is localized to steroidogenic cells of the brain and adrenal gland, and it modulates DHEA/DHEAS (show SULT2A1 Antibodies) homeostasis

  6. OSTbeta has roles in biological transport and is widely expressed in human tissues

  7. overexpr (show OSTALPHA Antibodies)ession of human OSTalpha and OSTbeta facilitated the uptake of conjugated chenodeoxycholate (show NR1H4 Antibodies) and the activation of FXR target genes

  8. OSTalpha (show OSTALPHA Antibodies)/OSTbeta expression is induced by bile acids through ligand-dependent transactivation of both OST (show DDOST Antibodies) genes by the nuclear bile acid receptor (show NR1H4 Antibodies)/farnesoid X receptor (show xpr1 Antibodies) (FXR (show NR1H4 Antibodies)).

  9. the selective localization of OSTalpha (show OSTALPHA Antibodies) and OSTbeta to the basolateral plasma membrane of epithelial cells responsible for bile acid and sterol reabsorption.

  10. These results indicate that expression of Ostalpha (show OSTALPHA Antibodies) and Ostbeta are highly regulated in response to cholestasis and that this response is dependent on the FXR bile acid receptor (show NR1H4 Antibodies).

Mouse (Murine) Organic Solute Transporter beta (OSTBETA) interaction partners

  1. Co-expression of mouse Ostalpha (show OSTALPHA Antibodies)-Ostbeta, but not the individual subunits, stimulated Na(+)-independent bile acid uptake and the apical-to-basolateral transport of taurocholate

  2. OSTalpha (show OSTALPHA Antibodies) and OSTbeta mRNA levels were induced in the adrenals and kidneys of wild-type, but not FXR (show NR1H4 Antibodies)-/-, mice

  3. the selective localization of OSTalpha (show OSTALPHA Antibodies) and OSTbeta to the basolateral plasma membrane of epithelial cells responsible for bile acid and sterol reabsorption.

  4. In conclusion, we identified Ost-alpha (show OSTALPHA Antibodies)/Ost-beta as a novel FXR (show NR1H4 Antibodies) target. Absent Ost-alpha (show OSTALPHA Antibodies)/Ost-beta induction in CA-fed FXR (show NR1H4 Antibodies)(-/-) animals may contribute to increased liver injury in these animals.

  5. The mouse Ostalpha (show OSTALPHA Antibodies) and Ostbeta promoters are unusual in that they contain functional FXR (show NR1H4 Antibodies) and LRH elements, which mediate, respectively, positive and negative feedback regulation by bile acids.

  6. These results indicate that expression of Ostalpha (show OSTALPHA Antibodies) and Ostbeta are highly regulated in response to cholestasis and that this response is dependent on the FXR bile acid receptor (show NR1H4 Antibodies).

  7. LXRalpha (show NR1H3 Antibodies) transcriptionally regulate mouse organic solute transporter alpha (show OSTALPHA Antibodies)/beta via inverted repeat-1 elements shared with farnesoid X receptor (show xpr1 Antibodies)

  8. Present as heterodimers (with Ost alpha (show OSTALPHA Antibodies)) and/or heteromultimers; the interaction between Ostalpha (show OSTALPHA Antibodies) and Ostbeta increases the stability of the proteins and is required for delivery of the heteromeric complex to the plasma membrane.

  9. These data indicate that Ostalpha (show OSTALPHA Antibodies)-Ostbeta is essential for intestinal bile acid transport in mice.

  10. These findings provide direct support for the hypothesis that Ostalpha (show OSTALPHA Antibodies)-Ostbeta is a major basolateral transporter of bile acids and conjugated steroids in the intestine, kidney, and liver.

Organic Solute Transporter beta (OSTBETA) Antigen Profile

Protein Summary

Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids (By similarity).

Gene names and symbols associated with OSTBETA

  • solute carrier family 51, beta subunit (Slc51b) antibody
  • organic solute transporter beta (SLC51B) antibody
  • solute carrier family 51, beta subunit (SLC51B) antibody
  • OSTB antibody
  • OSTBETA antibody
  • RGD1565748 antibody

Protein level used designations for OSTBETA

organic solute transporter beta , OST-beta , organic solute transporter subunit beta , solute carrier family 51 subunit beta , organic solute transporter beta subunit , Ost beta

GENE ID SPECIES
300790 Rattus norvegicus
507185 Bos taurus
123264 Homo sapiens
330962 Mus musculus
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