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Otospiralin Proteins (OTOS)

Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003 [PubMed 12687421]).[supplied by OMIM, Mar 2008].. Additionally we are shipping Otospiralin Antibodies (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OTOS 150677 Q8NHW6
OTOS 260301 Q8R448
OTOS 246044 Q8K560
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Top Otospiralin Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Guinea Pig His tag   1 mg Log in to see 56 to 66 Days
$2,073.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,075.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

OTOS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Otospiralin (OTOS) Interaction Partners

Human Otospiralin (OTOS) interaction partners

  1. study indicates a potentially protective role for the variant G alleles of SNPs rs77124181 and rs2291767 in Otos against the development of cisplatin-induced ototoxicity

  2. OTOSP spans 1630 nucleotides, has 4 exons & encodes a 567-base cDNA. OTOSP is on chromosome 2 at position q37.3. Beside intronic polymorphisms, a rare variant (Pro7Leu) was found in deafness patients & controls, excluding it as a genetic deafness gene.

Mouse (Murine) Otospiralin (OTOS) interaction partners

  1. Data suggest that impairment of fibrocytes caused by the loss in otospiralin leads to abnormal cochlear physiology and auditory function.

  2. Collectively, our observations suggest that otospiralin is possibly involved in signaling pathways, and could play a role in repair mechanisms subsequent to an injury in the central nervous system.

Otospiralin (OTOS) Protein Profile

Protein Summary

Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003

Gene names and symbols associated with Otospiralin Proteins (OTOS)

  • otospiralin (otos-b)
  • otospiralin (OTOS)
  • otospiralin (otos-a)
  • otospiralin (otos)
  • otospiralin (Otos)
  • MGC85248 protein
  • MGC148549 protein
  • otos protein
  • otosa protein
  • otosb protein
  • OTOSP protein

Protein level used designations for Otospiralin Proteins (OTOS)

otospiralin , otospiralin b , otospiralin a , organ of Corti 10 kDa protein

GENE ID SPECIES
447088 Xenopus laevis
460063 Pan troglodytes
477428 Canis lupus familiaris
494788 Xenopus laevis
617392 Bos taurus
698202 Macaca mulatta
100124976 Xenopus (Silurana) tropicalis
150677 Homo sapiens
260301 Mus musculus
246044 Rattus norvegicus
100135590 Cavia porcellus
Selected quality suppliers for Otospiralin Proteins (OTOS)
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