anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) Antibodies

OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. Additionally we are shipping OLR1 Kits (68) and OLR1 Proteins (30) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OLR1 4973 P78380
OLR1 108078 Q9EQ09
OLR1 140914 O70156
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Top anti-OLR1 Antibodies at antibodies-online.com

Showing 10 out of 221 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of OLR1 Antibody (Center) (ABIN652795) in HL-60 cell line lysates (35 µg/lane).OLR1 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of OLR1 (arrow) using rabbit polyclonal OLR1 Antibody (Center) (ABIN652795). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the OLR1 gene (Lane 2) . 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rat PE FACS Detection of LOX-1/OLR1 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse LOX-1/OLR1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$299.25
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged OLR1 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat aorta labeled with Anti-LOX-1 Polyclonal Antibody, Unconjugated (ABIN676988) followed by conjugation to the secondary antibody and DAB staining Human A549 cells probed with Rabbit Anti-LOX1 Polyclonal Antibody, Unconjugated . 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Un-conjugated Func, IF   0.1 mg Log in to see 6 to 8 Days
$599.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: LOX-1/OLR1 Antibody [NBP2-44314] - Analysis of Human Liver lysate (35ug protein in RIPA buffer). 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated WB Anti-LOX 1 antibody, Western blotting All lanes: Anti LOX 1  at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: SMMC Whole Cell Lysate at 40ug Lane 3: U87 Whole Cell Lysate at 40ug Lane 4: U937 Whole Cell Lysate at 40ug Lane 5: K562 Whole Cell Lysate at 40ug Predicted bind size:31 KD Observed bind size: 31KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB Anti- LOX1 antibody, Western blotting All lanes: Anti LOX1  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: HELA Whole Cell Lysate at 40ug Lane 3: K562 Whole Cell Lysate at 40ug Lane 4: HELA Whole Cell Lysate at 40ug Lane 5: RAJI Whole Cell Lysate at 40ug Predicted bind size: 31KD Observed bind size: 38KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-OLR1 Antibody Titration: 2.5ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: LOX-1/OLR1 Antibody [NBP2-27298] - Formalin-fixed, paraffin-embedded human brain stained with LOX-1 antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen. 0.1 mg Log in to see 7 to 9 Days
$317.63
Details

OLR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-OLR1 Antibodies

  1. Human Polyclonal OLR1 Primary Antibody for IF (p), IHC (p) - ABIN676988 : Wu, Tang, Jiang, Li, Jiang, Liu: PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. in Molecular and cellular biochemistry 2011 (PubMed)
    Show all 6 references for 676988

  2. Human Monoclonal OLR1 Primary Antibody for ELISA - ABIN393293 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 393293

  3. Human Monoclonal OLR1 Primary Antibody for Func, IF - ABIN1108520 : NOYES, DOMM, WILLSLC: Regulation of erythropoiesis. I. Erythropoietin assay as a clinical tool. in Blood 1970 (PubMed)
    Show all 4 references for 1108520

  4. Mouse (Murine) Monoclonal OLR1 Primary Antibody for FACS - ABIN4897693 : Biedroń, Konopiński, Marcinkiewicz, Józefowski: Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. in PLoS ONE 2015 (PubMed)
    Show all 2 references for 4897693

  5. Human Polyclonal OLR1 Primary Antibody for ICC, IF - ABIN4331395 : Chen, Qiu, Lin, Nam, Ogbu-Nwobodo, Archibald, Joslin, Wun, Sawamura, Green: Lectin-like oxidized low-density lipoprotein receptor (LOX-1) in sickle cell disease vasculopathy. in Blood cells, molecules & diseases 2016 (PubMed)

  6. Human Polyclonal OLR1 Primary Antibody for ELISA, WB - ABIN4331396 : Shi, Cosentino, Camici, Akhmedov, Vanhoutte, Tanner, Lüscher: Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2011 (PubMed)

  7. Human Polyclonal OLR1 Primary Antibody for IHC (p), WB - ABIN652795 : Predazzi, Martínez-Labarga, Vecchione, Mango, Ciccacci, Amati, Ottoni, Crawford, Rickards, Romeo, Novelli: Population differences in allele frequencies at the OLR1 locus may suggest geographic disparities in cardiovascular risk events. in Annals of human biology 2010 (PubMed)

More Antibodies against OLR1 Interaction Partners

Rabbit Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. ox-LDL and LOX-1 increase due to subarachnoid hemorrhage and they may play a role in the pathogenesis of vasospasm.

  2. LOX (show LOX Antibodies) and LOXL2 (show LOXL2 Antibodies) play an important role in wound healing after glaucoma filtration surgery. Targeting LOXL2 (show LOXL2 Antibodies) with an inhibitory monoclonal antibody (GS-607601) had a broader efficacy than targeting LOX (show LOX Antibodies), reducing angiogenesis and inflammation, and fibrosis.

  3. Angiotensin (1-7) inhibited LOX-1 expression and diminished Ang II (show AGT Antibodies)-mediated inflammation in endothelial cells

  4. Elevated LOX-1 expression and inflammatory responses are induced in hypercholesterolemic rabbits by Chlamydia pneumoniae GroEL1 heat shock protein.

  5. Early treatment with fluvastatin had a crucial endothelial protective effect by down-regulating LOX-1 expression level in atherosclerotic arteries in early atherosclerosis.

  6. LOX-1 expression appears to be closely associated with tissue factor (show F3 Antibodies) expression, apoptotic events and morphological vulnerability in atherosclerotic lesions

Human Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. Berberine could prevent the oxLDL and TNFalpha (show TNF Antibodies) - induced LOX1 expression and oxidative stress, key events that lead to NOX, MAPK (show MAPK1 Antibodies)/Erk1/2 (show MAPK1/3 Antibodies) and NF-kappaB (show NFKB1 Antibodies) activation linked to endothelial dysfunction.

  2. Data suggest Klotho (show KL Antibodies) attenuates ox-LDL- (oxidized low density lipoprotein)-induced oxidative stress in vascular endothelial cells via up-regulation of oxidative scavengers (lipoprotein and nitric oxide), activation of the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/eNOS (show NOS3 Antibodies) signaling, and down-regulation of LOX1 (lectin-like ox-LDL receptor (show LDLR Antibodies)) expression. (PI3K (show PIK3CA Antibodies) = phosphatidylinositol 3-Kinase; Akt (show AKT1 Antibodies) = proto-oncogene c-Akt (show AKT1 Antibodies); eNOS (show NOS3 Antibodies) = endothelial nitric oxide synthase (show NOS3 Antibodies))

  3. Individuals >/=30 years old with abdominal obesity presented lower Lox1 levels than patients >/=30 years old without abdominal obesity.

  4. These studies suggest that activation of LOX-1 expression occurs through binding of the chlamydial glycan and provides one mechanism by which Chlamydia pneumoniae infection could play a role in the pathogenesis of atherosclerosis.

  5. Elevated LOX1 is Associated with Acute Stroke.

  6. Xanthine oxidase (show XDH Antibodies) induces foam cell formation in large part through activation of LOX-1 - NLRP3 (show NLRP3 Antibodies) pathway in both vascular smooth muscle cells and THP-1 (show GLI2 Antibodies) cells.

  7. show that MiR (show MLXIP Antibodies)-590-5p inhibits angiogenesis by targeting LOX-1 and suppressing redox-sensitive signals

  8. OLR1 rs1050286 SNP may contribute to modify OLR1 susceptibility to acute myocardial infarction and coronary artery diseases.

  9. Serum sLOX-1 level was significantly lower in the restless legs syndrome patient group compared to controls.

  10. The mechanistic link between miR (show MLXIP Antibodies)-590-5p and LOX-1:miR (show MLXIP Antibodies)-590-5p downregulation led to LOX-1 upregulation in endothelial cells.

Mouse (Murine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. LOX-1 in cardiomyocytes plays an important role in the pathology of doxorubicin-induced cardiomyopathy. LOX-1 deletion altered the LOX-1-related signaling pathway, which led to improvements in cardiac function, myocardial inflammation, fibrosis and degenerative changes after DOX treatment.

  2. Therefore we concluded that HNG (show NRGN Antibodies) could inhibit ox-LDL-induced macrophage-derived foam cell formation, which occurs because of a decrease in lipid uptake and an increase in cholesterol efflux from macrophage cells.

  3. The study indicated that the LOX-1/ox-LDL system in chondrocytes plays a role in the pathogenesis of age-related knee knee osteoarthritis, which is potentially a target for preventing knee osteoarthritis progression.

  4. We demonstrated that varenicline upregulates expression of LOX-1 and CD36 (show CD36 Antibodies) significantly through alpha7 nAChR (show CHRNA7 Antibodies), thereby promoting oxLDL uptake in macrophages.

  5. this study shows that LOX-1 can regulate inflammation through regulation of generation of reactive oxygen species in in Aspergillus fumigatus keratitis

  6. The in vitro and in vivo models revealed that lipid metabolism disorder and FK506 caused oxidative stress and a fibrogenic response. In addition, decreased levels of LOX1 markedly reduced the levels of TGFb1 (show TGFB1 Antibodies) in the in vitro model.

  7. LOX-1/ox-LDL system plays a pivotal role in the pathogenesis of instability-induced osteoarthritis through endochondral ossification.

  8. that ox-LDL receptor-1 and PCSK9 (show PCSK9 Antibodies) positively influence each other's expression, especially during an inflammatory reaction

  9. LOX1 is implicated in OxLDLinduced oxidative stress of macrophages in atherosclerosis, which in part, involves the regulation of NADPH (show FDXR Antibodies) oxidases.

  10. LOX-1 is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (show CAPN1 Antibodies) and -2.

Cow (Bovine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. bta-miR (show MYLIP Antibodies)-370 has a negative regulatory effect on the OLR1 gene at both the gene and protein expression levels and has a role in lipid metabolism in bovine adipocytes

  2. Overexpression of LOX-1 leads to the attenuation of protective autophagy response in aortic endothelial cells.

  3. These results imply that the 3' UTR (show UTS2R Antibodies) SNP of the OLR1 gene is a strong candidate marker for selection in cattle breeding programs.

  4. Our data indicate that blocking the LOX-1 receptor signal pathway might be a promising way to improve steroid hormone concentrations in metabolically highly active female mammals

  5. In the present study, we show that inhibition of LOX-1 leads to a rearrangement of ceramide from the basal membrane toward the Golgi apparatus

  6. The downregulation of eNOS (show NOS3 Antibodies) by ox-low-density lipoprotein, as driven by LOX-1-mediated endoplasmic stress, is associated with the PI3K-Akt (show AKT1 Antibodies)-eNOS (show NOS3 Antibodies) signaling pathway.

  7. 3'-UTR (show UTS2R Antibodies) SNP assoicated with milk composition traits and somatic cell score

  8. Oxidized low-density lipoprotein receptor (show LDLR Antibodies) (OLR1) single nucleotide polymorphism haplotype is associated with milk fat yield and fat percentage

  9. synergistic effects of cyclic tensile stretch load and ox-LDL on cell viability and proteoglycan (show Vcan Antibodies) synthesis in chondrocytes, which may be mediated through enhanced expression of LOX-1

  10. Upregulates VEGF (show VEGFA Antibodies) expression in articular cartilage, at least in part, through activation of PPAR-gamma (show PPARG Antibodies).

OLR1 Antigen Profile

Protein Summary

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with OLR1

  • oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1) antibody
  • lectin-like oxidized LDL receptor (LOX-1) antibody
  • oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1) antibody
  • CLEC8A antibody
  • LOX-1 antibody
  • LOX1 antibody
  • LOXIN antibody
  • Oldlr1 antibody
  • Oldr1 antibody
  • Olr1 antibody
  • PLOX-1 antibody
  • Scare1 antibody
  • SLOX1 antibody
  • SR-EI antibody

Protein level used designations for OLR1

oxidised low density lipoprotein (lectin-like) receptor 1 , oxidized low density lipoprotein (lectin-like) receptor 1 , lectin-like oxLDL receptor 1 , lectin-like oxidized LDL receptor 1 , lectin-type oxidized LDL receptor 1 , ox-LDL receptor 1 , oxidized low-density lipoprotein receptor 1 , C-type lectin domain family 8 member A , hLOX-1 , ox LDL receptor 1 , oxidized low-density lipoprotein receptor 1, soluble form , scavenger receptor class E, member 1 , Lectin-like oxidized low-density lipoprotein receptor-1 , lectin-like oxidized low-density lipoprotein receptor , BLOX1 , LOX-1 , bLOX-1 , lectin-like oxidized LDL receptor-1 , oxidized low density lipoprotein receptor 1

GENE ID SPECIES
473362 Pan troglodytes
486694 Canis lupus familiaris
100009322 Oryctolagus cuniculus
4973 Homo sapiens
108078 Mus musculus
140914 Rattus norvegicus
281368 Bos taurus
396724 Sus scrofa
Selected quality suppliers for anti-OLR1 (OLR1) Antibodies
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