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Acts as a transcritpional repressor. Additionally we are shipping PHF19 Proteins (3) and many more products for this protein.
Showing 10 out of 43 products:
Human Polyclonal PHF19 Primary Antibody for WB - ABIN2784153
Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005
G9a (show EHMT2 Antibodies) promotes H3K27 methylation of the E-cadherin (show CDH1 Antibodies) promoter by upregulating PCL3 to increase PRC2 promoter recruitment and by downregulating the H3K27 demethylase (show MBD2 Antibodies) KDM7A (show JHDM1D Antibodies) to silence E-cadherin (show CDH1 Antibodies) gene
These results provide evidence that PHF19 promotes Hepatocellular carcinoma and is regulated by the tumor-suppressor, miR (show MLXIP Antibodies)-195-5p
The histone H3K36me3 binding by the Tudor domains of PHF1 (show PHF1 Antibodies), PHF19 and likely MTF2 (show MTF2 Antibodies) provide another recruitment and regulatory mechanism for the PRC2 complex
propose a model whereby PHF19 functions during mouse embryonic stem cell differentiation to transiently bind the H3K36me3 mark via its Tudor domain
PHF19 silencing reduces the cell proliferation rate and increases the transendothelial migration capacities of melanoma cell lines.
Functional characterization of human Polycomb-like 3 isoforms identifies them as components of distinct EZH2 (show EZH2 Antibodies) protein complexes
identification of a gene encoding a human homologue of the Drosophila polycomblike protein, hPCL3 gene, encoding two nuclear proteins, hPCL3S and hPCL3L; markedly overexpressed in many types of cancers
Acts as a transcritpional repressor. Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter.
PHD finger protein 19
, PHD finger protein 19-like
, polycomb like 3
, polycomb-like 3
, polycomb-like protein 3
, tudor domain containing 19B