PROP Paired-Like Homeobox 1 Proteins (PROP1)

PROP1 encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Additionally we are shipping PROP1 Antibodies (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PROP1 19127 P97458
PROP1 5626 O75360
Rat PROP1 PROP1 266738  
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Top PROP1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Yeast Wild boar His tag   1 mg Log in to see 60 to 71 Days
$2,566.67
Details
Yeast REACT_Howler monkey His tag   1 mg Log in to see 60 to 71 Days
$2,566.67
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Yeast REACT_Old World Monkey His tag   1 mg Log in to see 60 to 71 Days
$2,566.67
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Yeast Primate His tag   1 mg Log in to see 60 to 71 Days
$2,566.67
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Yeast Dog His tag   1 mg Log in to see 60 to 71 Days
$2,566.67
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,566.67
Details

PROP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

Top referenced PROP1 Proteins

  1. Human PROP1 Protein expressed in HEK-293 Cells - ABIN2729760 : Bando, Iguchi, Fukuoka, Yamamoto, Hidaka-Takeno, Okimura, Matsumoto, Suda, Nishizawa, Takahashi, Tojo, Takahashi: Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome. in The Journal of clinical endocrinology and metabolism 2014 (PubMed)

More Proteins for PROP Paired-Like Homeobox 1 (PROP1) Interaction Partners

Mouse (Murine) PROP Paired-Like Homeobox 1 (PROP1) interaction partners

  1. SOX2 (show SOX2 Proteins) is a regulatory factor of Prop1 expression

  2. Data show that human paired like homeodomain factor 1 (PROP1) can substitute functionally for mouse Prop1.

  3. endocochlear potential and KCNJ10 (show KCNJ10 Proteins) immunostaining in the stria vascularis are indistinguishable from wild type, and no differences in neurofilament or synaptophysin (show SYP Proteins) staining are evident in Prop1(df) mutants

  4. Data report the spatial and temporal regulation of Otx2 (show OTX2 Proteins) in normal mice and Prop1 mutant.

  5. Several components of the main GH-signaling pathways exhibit enhanced sensitivity to the hormone in liver and muscle of Ames dwarf mice.

  6. Studies suggest that TLE1 (show TLE1 Proteins) and TLE3 might also play roles independent of HESX1 (show HESX1 Proteins) by interacting with other transcription factors like PROP1.

  7. Lhx4 (show LHX4 Proteins) and Prop1 have critical, but mechanistically different roles in specification and expansion of specialized anterior pituitary cells

  8. Tcf4 (show TCF4 Proteins) and Aes (show AES Proteins) influence pituitary growth and development, and place Tcf4 (show TCF4 Proteins) and Tle3 in the genetic hierarchy with Prop1

  9. PROP1 has a role in pituitary gland growth

  10. variation in PROP1 expression could affect the growth spurt (show BPIFA1 Proteins) and the onset of puberty in humans.

Human PROP Paired-Like Homeobox 1 (PROP1) interaction partners

  1. GH replacement successfully corrects the growth deficit in children with Growth Hormone (show GH1 Proteins) Deficiency . While the genetic aetiology remains undefined in most cases of Isolated Growth Hormone (show GH1 Proteins) Deficiency , PROP1 mutations constitute a major cause for Multiple Pituitary Hormone (show CGA Proteins) Deficiencies. Persistence of Growth Hormone (show GH1 Proteins) Deficiency into adulthood is related to abnormal pituitary morphology.

  2. The present study reports on screening of POU1F1 (show POU1F1 Proteins), PROP1, and HESX1 (show HESX1 Proteins) in combined pituitary hormone (show CGA Proteins) deficiency patients and the novel variations identified.

  3. A compound heterozygosity in the PROP1 gene has been identified for both probands. The first change represents a mutational hot spot (c.150delA, p.R53fsX164), whereas the second is a novel alteration (p.R112X) that leads to protein disruption. The resulting clinical phenotype was surprisingly distinct compared to most patients with genetic alterations in PROP1.

  4. the most frequent variants in the PROP1 gene are not a consequence of variant hot spots as previously assumed, but are founder variants.

  5. Data show that human paired like homeodomain factor 1 (PROP1) can substitute functionally for mouse Prop1.

  6. A novel heterozygous mutation in the HESX1 (show HESX1 Proteins) gene and a novel homozygous mutation in the PROP1 gene were detected in 2 pedigrees with combined pituitary hormone (show CGA Proteins) deficiency

  7. The c.301_302delAG homozygous genotype had a high frequency of 38%, reaching 100% in group with familial cases of multiple pituitary hormone (show CGA Proteins) deficiency and 16% in group with sporadic forms of MPHD.

  8. investigated the specific mutations in PROP1, POU1F1 (show POU1F1 Proteins), LHX3 (show LHX3 Proteins), and HESX1 (show HESX1 Proteins) genes in patients with combined pituitary hormone (show CGA Proteins) deficiency (CPHD) in Turkey

  9. The p.R73C PROP1 mutation was the most frequent mutation in Congenital hypopituitarism in a Moroccan cohort.

  10. The various levels of specific miRNAs, particularly miR (show MLXIP Proteins)-593 and miR (show MLXIP Proteins)-511 whose direct target is the PROP1 gene, may serve as a non-invasive diagnostic biomarkers for children with CPHD.

Pig (Porcine) PROP Paired-Like Homeobox 1 (PROP1) interaction partners

  1. Data suggest that formation of a heterodimer between HESX1 (show HESX1 Proteins) and PROP1 allows HESX1 (show HESX1 Proteins) to become active, and that PROP1 then replaces HESX1 (show HESX1 Proteins) to advance to the middle stage of pituitary development.

  2. Prop-1 participates in the regulation of FSHbeta gene

  3. Prop-1 might be involved in development of gonadotropes and hormone production

  4. Dimeric binding of PROP1 is able to recognize diverse palindromic TAAT sequences separated by 3 nucleotides and to exhibit its transcriptional activity.

Cow (Bovine) PROP Paired-Like Homeobox 1 (PROP1) interaction partners

  1. The H173R mutation in PROP1 can be considered as a DNA marker for selecting individuals with superior growth traits, thereby contributing to research on breeding and genetics in the beef industry.

PROP1 Protein Profile

Protein Summary

This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone.

Gene names and symbols associated with PROP1

  • paired like homeodomain factor 1 (Prop1)
  • PROP paired-like homeobox 1 (PROP1)
  • PROP paired-like homeobox 1 (Prop1)
  • CPHD2 protein
  • df protein
  • PROP-1 protein

Protein level used designations for PROP1

Ames dwarf , homeobox protein prophet of Pit-1 , pituitary specific homeodomain factor , pituitary-specific homeodomain factor , prophet of Pit-1 , PROP paired-like homeobox 1 , prophet of Pit1, paired-like homeodomain transcription factor , PROP-1 , paired like homeodomain factor 1 , prophet of Pit1 paired-like homeodomain transcription factor

GENE ID SPECIES
19127 Mus musculus
374220 Gallus gallus
5626 Homo sapiens
474647 Canis lupus familiaris
397280 Sus scrofa
282563 Bos taurus
266738 Rattus norvegicus
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