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anti-Paired Related Homeobox 1 (PRRX1) Antibodies

The DNA-associated protein encoded by PRRX1 is a member of the paired family of homeobox proteins localized to the nucleus. Additionally we are shipping PRRX1 Proteins (8) and PRRX1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRRX1 5396 P54821
PRRX1 18933 P63013
PRRX1 266813 P63014
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Top anti-PRRX1 Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN238608 (1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB PRRX1 Antibody (C-term) (ABIN1881690) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the PRRX1 antibody detected the PRRX1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ICC, IF, IHC (p), IHC, ELISA, WB Western Blot: PRRX1 Antibody [NBP1-06067] - (1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$447.56
Details
Human Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of PRRX1 expression in transfected 293T cell line by PRRX1 monoclonal antibody (M01), clone 1E2.Lane 1: PRRX1 transfected lysate (Predicted MW: 24.4 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged PRRX1 is 0.03 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: PRRX1 Antibody [NBP2-13816] - Staining of human testis shows strong nuclear positivity in cells in seminiferus ducts. Immunocytochemistry/Immunofluorescence: PRRX1 Antibody [NBP2-13816] - Staining of human cell line HeLa shows positivity in nucleus and nucleoli. 0.1 mL Log in to see 7 to 9 Days
$439.69
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Prrx1  Sample Tissue: Rat Pancreas lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot (WB) analysis of Jurkat cells using PRX1 Polyclonal Antibody. 100 μL Log in to see 14 Days
$175.80
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details

PRRX1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-PRRX1 Antibodies

  1. Human Polyclonal PRRX1 Primary Antibody for IHC, IHC (p) - ABIN4348068 : Hardin, Guo, Shan, Montemayor-Garcia, Asioli, Yu, Harrison, Chen, Lloyd: The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression. in The American journal of pathology 2014 (PubMed)
    Show all 3 references for ABIN4348068

  2. Human Polyclonal PRRX1 Primary Antibody for WB - ABIN1881690 : Jiang, Stefanovic: Homeobox gene Prx1 is expressed in activated hepatic stellate cells and transactivates collagen alpha1(I) promoter. in Experimental biology and medicine (Maywood, N.J.) 2008 (PubMed)
    Show all 3 references for ABIN1881690

  3. Human Polyclonal PRRX1 Primary Antibody for ICC, IF - ABIN449553 : Reichert, Takano, von Burstin, Kim, Lee, Ihida-Stansbury, Hahn, Heeg, Schneider, Rhim, Stanger, Rustgi: The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis. in Genes & development 2013 (PubMed)
    Show all 2 references for ABIN449553

  4. Human Polyclonal PRRX1 Primary Antibody for WB - ABIN374895 : Kim, Ahn, Liang, Ip, Zhang, Park: Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology. in Cancer research 2007 (PubMed)

  5. Human Monoclonal PRRX1 Primary Antibody for ELISA, WB - ABIN1327183 : Hirata, Sugimachi, Takahashi, Ueda, Sakimura, Uchi, Kurashige, Takano, Nanbara, Komatsu, Saito, Shinden, Iguchi, Eguchi, Atsumi, Sakamoto, Doi, Hirakawa, Honda, Mimori: Downregulation of PRRX1 Confers Cancer Stem Cell-Like Properties and Predicts Poor Prognosis in Hepatocellular Carcinoma. in Annals of surgical oncology 2014 (PubMed)

More Antibodies against PRRX1 Interaction Partners

Human Paired Related Homeobox 1 (PRRX1) interaction partners

  1. miR (show MLXIP Antibodies)-655 inhibits the acquisition of the epithelial-mesenchymal transition phenotype in triple-negative breast cancer by down-regulating Prrx1, thereby inhibiting cell migration and invasion during cancer progression.

  2. Decreased Expression of PRRX1 was Associated with Hepatocellular Carcinoma.

  3. the switch from Prrx1b to Prrx1a governs EMT (show ITK Antibodies) plasticity in both mouse models of PDAC and human PDAC

  4. These findings demonstrate that PRRX1 promotes epithelial-mesenchymal transition in gastric cancer cells

  5. Our results indicate that activation of Notch (show NOTCH1 Antibodies) signaling by PRRX1 is associated with the promotion of glioblastoma cell invasion.

  6. We conclude that miR (show MLXIP Antibodies)-146b-5p has a role in cell proliferation and invasion, and that PRRX1 plays an important role in papillary thyroid carcinoma epithelial-mesenchymal transition and disease progression.

  7. Overexpression of PRRX1 in stably overexpressed-miR (show MLXIP Antibodies)-124 cell lines could rescue the effects of radiosensitivity enhancement brought by miR (show MLXIP Antibodies)-124.

  8. In the rare variant joint analysis, damaging variants within the PRRX1 region showed significant association with AF.

  9. PRRX1 is an indicator of metastasis and poor prognosis in colorectal cancer cases.

  10. We show that the homeobox (show Lbx1 Antibodies) factor Prrx1 is an EMT (show ITK Antibodies) inducer conferring migratory and invasive properties. The loss of Prrx1 is required for cancer cells to metastasize in vivo, which revert to the epithelial phenotype concomitant with the acquisition of stem cell properties.

Mouse (Murine) Paired Related Homeobox 1 (PRRX1) interaction partners

  1. Data show that p38alpha (show MAPK14 Antibodies) mitogen-activated protein kinase (show MAPK1 Antibodies) (MAPK (show MAPK1 Antibodies)) in paired related homeobox 1 protein (Prx1 (show PRDX1 Antibodies)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG (show TNFRSF11B Antibodies)) production.

  2. These data suggest the presence of a novel oxidative-stress-handling pathway where the anti-p53 (show TP53 Antibodies) molecule fortilin (show TPT1 Antibodies) augments the peroxidase PRX1 (show PRDX1 Antibodies) by protecting it against degradation and inactivation of the enzyme.

  3. Induction of Prx1 (show PRDX1 Antibodies) by hypoxia regulates heme oxygenase-1 (show HMOX1 Antibodies) via NF-kappaB (show NFKB1 Antibodies) in oral cancer.

  4. PRX-1 has a regulatory role in NF-kappaB (show NFKB1 Antibodies) nuclear translocation.

  5. The data of this study suggested that Prx1 (show PRDX1 Antibodies) plays an important role as a key switch for neural cell lineage determination and the maintenance of the self-renewal of adult NSCs at several stages in the adult brain.

  6. These observations suggest that increased Prrx1 expression may promote TGFbeta (show TGFB1 Antibodies) activity in adipose tissue and thereby contribute to aberrant adipocyte function during obesity.

  7. The two isoforms, Prrx1a and Prrx1b, regulate migration and invasion, respectively, in pancreatic cancer cells

  8. The results suggested that scarless skin-wound healing may require activation of the prx1 (show PRDX1 Antibodies) limb enhancer, and competence to activate the enhancer is probably a prerequisite for epimorphic regeneration, such as limb regeneration.

  9. These results identify the homeobox protein (show HOXA1 Antibodies) Prx1 (show PRDX1 Antibodies) as an obligate mediator of TNF (show TNF Antibodies) inhibition of Osx (show SP7 Antibodies) and differentiation of osteoblast progenitors.

  10. Generation of Ctgf (show CTGF Antibodies)(+/LacZ (show GLB1 Antibodies)) heterozygous null mice and tissue-specific null Ctgf (show CTGF Antibodies) mice, where Ctgf (show CTGF Antibodies) is flanked by lox (show LOX Antibodies) sequences with mice expressing the Cre recombinase (show RAG1 Antibodies) under the control of the paired-related homeobox gene 1 (Prx1 (show PRDX1 Antibodies)) enhancer (Prx1 (show PRDX1 Antibodies)-Cre).

PRRX1 Antigen Profile

Protein Summary

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.

Gene names and symbols associated with PRRX1

  • paired related homeobox 1a (prrx1a) antibody
  • paired related homeobox 1 (PRRX1) antibody
  • similar to PEPP subfamily gene 2 (PRRX1) antibody
  • paired related homeobox 1 (Prrx1) antibody
  • A230024N07Rik antibody
  • AA755424 antibody
  • AGOTC antibody
  • AI385634 antibody
  • AI843499 antibody
  • cb329 antibody
  • gMHox antibody
  • homeobox antibody
  • K-2 antibody
  • mHox antibody
  • PHOX1 antibody
  • Pmx antibody
  • Pmx1 antibody
  • PRRX1 antibody
  • Prx-1 antibody
  • Prx1 antibody
  • wu:fa09h05 antibody
  • wu:fb52c01 antibody
  • zgc:64055 antibody

Protein level used designations for PRRX1

paired mesoderm homeo box 1 , paired related homeobox 1 , prx1 , paired mesoderm homeobox 1 , paired mesoderm homeobox protein 1 , similar to PEPP subfamily gene 2 , homeobox protein PHOX1 , paired mesoderm homeobox 1 isoform pmx-1b , paired-related homeobox protein 1 , homeobox protein K-2 , homeobox protein mHox , rHox , homeobox protein MHOX , paired-related homeotic gene product

GENE ID SPECIES
406431 Danio rerio
540901 Bos taurus
609105 Canis lupus familiaris
702704 Macaca mulatta
736677 Pan troglodytes
695352 Macaca mulatta
5396 Homo sapiens
18933 Mus musculus
266813 Rattus norvegicus
373941 Gallus gallus
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