anti-Peptidyl-tRNA Hydrolase 2 (PTRH2) Antibodies

The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity). Additionally we are shipping Peptidyl-tRNA Hydrolase 2 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTRH2 51651 Q9Y3E5
PTRH2 217057 Q8R2Y8
PTRH2 287593  
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Top anti-Peptidyl-tRNA Hydrolase 2 Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PTRH2 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Bit1 Antibody (K95) (ABIN650622) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane).This demonstrates the Bit1 antibody detected the Bit1 protein (arrow). Bit1 Antibody (Center) (ABIN650622)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB PTRH2 Antibody (N-term) (ABIN1881706) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the PTRH2 antibody detected the PTRH2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: PTRH2 Antibody [NBP1-88595] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Immunocytochemistry/Immunofluorescence: PTRH2 Antibody [NBP1-88595] - Staining of human cell line U-2 OS shows positivity in mitochondria. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with PTRH2 antibody ABIN213970 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Bit1 in Daudi cell lysate with Bit1 antibody using ABIN251972 at (A) 1, (B) 2, and (C) 4 ug/ml. 0.05 mg Log in to see 7 to 9 Days
$408.19
Details
Cow Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details

PTRH2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
, ,

, , , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Peptidyl-tRNA Hydrolase 2 Antibodies

  1. Human Polyclonal PTRH2 Primary Antibody for WB - ABIN1881706 : Fan, Jiang, Suo, Liu, Xu, Ji, Zhang, Yang: Down-regulation of the apoptosis-inducing factor or Bcl-2 inhibitor of transcription by RNA interference can alleviate TAp63gamma-induced apoptosis in esophageal squamous carcinoma EC9706 cells. in International journal of oncology 2009 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal PTRH2 Primary Antibody for ICC, IF - ABIN4348629 : Karmali, Brunquell, Tram, Ireland, Ruoslahti, Biliran: Metastasis of tumor cells is enhanced by downregulation of Bit1. in PLoS ONE 2011 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Peptidyl-tRNA Hydrolase 2 Interaction Partners

Human Peptidyl-tRNA Hydrolase 2 (PTRH2) interaction partners

  1. Bcl-2 (show BCL2 Antibodies) expression patterns in various differentiated esophageal squamous cell carcinoma were higher than those in corresponding normal esophageal tissues with no statistical differences ( p > 0.05). Importantly, Bit1 expression was positively correlated with both matrix metalloproteinase 2 (show MMP2 Antibodies) and Bcl-2 (show BCL2 Antibodies) expression in esophageal squamous cell carcinoma and esophageal adenocarcinoma tissues ( p < 0.05).

  2. Our data establishes a PTRH2 mutation as a n (show DMD Antibodies)ovel driver of (show DMD Antibodies) congenital muscle degeneration and identifies a potential novel target to treat muscle (show DMD Antibodies) myopathies.

  3. Bit1 may be an important regulator in cell growth, apoptosis, migration and invasion of esophageal squamous cell carcinoma via targeting FAK (show PTK2 Antibodies)-paxillin (show PXN Antibodies) pathway.

  4. these findings suggest a tumor suppressive role of the caspase-independent anoikis effector Bit1 in lung cancer.

  5. Reduction of the Bit1 level in cytosol, regulated by E2 binding to ESR1 (show ESR1 Antibodies), was mainly mediated through PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathways.

  6. Bit1 plays pivotal roles in the development and progression of ESCC, and its biological functions in ESCC may be closely associated with AIF (show AIFM1 Antibodies) and Bcl-2 (show BCL2 Antibodies) levels.

  7. TLE1 (show TLE1 Antibodies) inhibits the Bit1 anoikis pathway by reducing the formation of the proapoptotic Bit1-AES (show AES Antibodies) complex in part through sequestration of AES (show AES Antibodies) in the nucleus.

  8. Bit1 may be a useful pathological marker and a prognostic marker for serous papillary adenocarcinomas outcome.

  9. Data indicate that the cell death domain (CDD) to the N-terminal 62 amino acids of Bit1 was more potent in killing cells than the full-length Bit1 protein when equivalent amounts of cDNA were transfected.

  10. downregulation of Bit1 conferred cancer cells with enhanced anoikis resistance, adhesive and migratory properties in vitro

Mouse (Murine) Peptidyl-tRNA Hydrolase 2 (PTRH2) interaction partners

  1. Ptrh2 levels were up-regulated in dystrophin (show DMD Antibodies) deficient mdx (show DMD Antibodies) muscle, which correlates with the elevated levels of the a7b1 integrin observed in mdx (show DMD Antibodies) muscle and Duchenne muscular dystrophy (show DMD Antibodies) patients. Similar to the a7 integrin, Ptrh2 expression was decreased in laminin-a2 null gastrocnemius muscle

  2. These results support an unanticipated yet essential role for Bit-1 in controlling myogenesis through regulation of Bcl-2 (show BCL2 Antibodies).

  3. downregulation of Bit1 specifically potentiated tumor metastasis in vivo

  4. Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathway

  5. These studies establish the physiological significance of Bit1 activity and begin to delineate a Bit1 signaling pathway that acts through Erk (show EPHB2 Antibodies) regulation.

Peptidyl-tRNA Hydrolase 2 (PTRH2) Antigen Profile

Protein Summary

The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity).

Gene names and symbols associated with PTRH2

  • peptidyl-tRNA hydrolase 2 (ptrh2) antibody
  • peptidyl-tRNA hydrolase 2 (CC1G_10259) antibody
  • peptidyl-tRNA hydrolase 2 (ANI_1_1036184) antibody
  • peptidyl-tRNA hydrolase 2 (AOR_1_2082154) antibody
  • peptidyl-tRNA hydrolase 2 (PTRH2) antibody
  • peptidyl-tRNA hydrolase 2 (Ptrh2) antibody
  • A230072I16Rik antibody
  • Bit1 antibody
  • CGI-147 antibody
  • PTH2 antibody
  • RGD1306819 antibody
  • wu:fj09f02 antibody
  • zgc:109954 antibody

Protein level used designations for PTRH2

peptidyl-tRNA hydrolase 2 , PTH 2 , bcl-2 inhibitor of transcription 1 , peptidyl-tRNA hydrolase 2, mitochondrial , Bcl-2 inhibitor of transcription

GENE ID SPECIES
549411 Xenopus (Silurana) tropicalis
6005013 Coprinopsis cinerea okayama7130
4991038 Aspergillus niger CBS 513.88
5992240 Aspergillus oryzae RIB40
51651 Homo sapiens
217057 Mus musculus
791795 Danio rerio
417634 Gallus gallus
100682594 Canis lupus familiaris
516595 Bos taurus
287593 Rattus norvegicus
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