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PTRH2 Products

(Peptidyl-tRNA Hydrolase 2 (PTRH2))

Categories

The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity).

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Featured PTRH2 Categories

PTRH2 Antibodies

High quality antibodies with extensive validation data.

PTRH2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTRH2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6146480
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN5586599
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7162868
Quantity 100 μL
Datasheet Datasheet

Recommended PTRH2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6206891
Quantity 96 tests
Datasheet Datasheet

Recommended PTRH2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124339
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316893
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3086685
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PTRH2 products

Yao, Pham, Temple, Gray, Cannon, Chen, Abdel-Mageed, Biliran: "The Anoikis Effector Bit1 Inhibits EMT through Attenuation of TLE1-Mediated Repression of E-Cadherin in Lung Cancer Cells." in: PLoS ONE, Vol. 11, Issue 9, pp. e0163228, (2016) (PubMed).

Yao, Jennings, Ireland, Pham, Temple, Davis, Chen, Davenport, Biliran: "The anoikis effector Bit1 displays tumor suppressive function in lung cancer cells." in: PLoS ONE, Vol. 9, Issue 7, pp. e101564, (2014) (PubMed).

Brunquell, Biliran, Jennings, Ireland, Chen, Ruoslahti: "TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells." in: Molecular cancer research : MCR, Vol. 10, Issue 11, pp. 1482-95, (2012) (PubMed).

Karmali, Brunquell, Tram, Ireland, Ruoslahti, Biliran: "Metastasis of tumor cells is enhanced by downregulation of Bit1." in: PLoS ONE, Vol. 6, Issue 8, pp. e23840, (2011) (PubMed).

Fan, Jiang, Suo, Liu, Xu, Ji, Zhang, Yang: "Down-regulation of the apoptosis-inducing factor or Bcl-2 inhibitor of transcription by RNA interference can alleviate TAp63gamma-induced apoptosis in esophageal squamous carcinoma EC9706 cells." in: International journal of oncology, Vol. 35, Issue 2, pp. 359-67, (2009) (PubMed).

Biliran, Jan, Chen, Pasquale, Ruoslahti: "Protein kinase D is a positive regulator of Bit1 apoptotic function." in: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28029-37, (2008) (PubMed).

Bouchentouf, Benabdallah, Rousseau, Schwartz, Tremblay: "Induction of Anoikis following myoblast transplantation into SCID mouse muscles requires the Bit1 and FADD pathways." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 7, Issue 6, pp. 1491-505, (2007) (PubMed).

De Pereda, Waas, Jan, Ruoslahti, Schimmel, Pascual: "Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity." in: The Journal of biological chemistry, Vol. 279, Issue 9, pp. 8111-5, (2004) (PubMed).

Jan, Matter, Pai, Chen, Pilch, Komatsu, Ong, Fukuda, Ruoslahti: "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors." in: Cell, Vol. 116, Issue 5, pp. 751-62, (2004) (PubMed).

Martin, Vuori: "Regulation of Bcl-2 proteins during anoikis and amorphosis." in: Biochimica et biophysica acta, Vol. 1692, Issue 2-3, pp. 145-57, (2004) (PubMed).

Synonyms and alternative names related to PTRH2

peptidyl-tRNA hydrolase 2 (ptrh2), peptidyl-tRNA hydrolase 2 (CC1G_10259), peptidyl-tRNA hydrolase 2 (ANI_1_1036184), peptidyl-tRNA hydrolase 2 (AOR_1_2082154), peptidyl-tRNA hydrolase 2 (PTRH2), peptidyl-tRNA hydrolase 2 (Ptrh2), A230072I16Rik, BIT1, Bit1, CGI-147, PTH2, RGD1306819, wu:fj09f02, zgc:109954

Protein level used designations for PTRH2

  • peptidyl-tRNA hydrolase 2
  • PTH 2
  • bcl-2 inhibitor of transcription 1
  • peptidyl-tRNA hydrolase 2, mitochondrial
  • Bcl-2 inhibitor of transcription
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