Peptidyl-tRNA Hydrolase 2 Proteins (PTRH2)

The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity). Additionally we are shipping Peptidyl-tRNA Hydrolase 2 Antibodies (87) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTRH2 51651 Q9Y3E5
PTRH2 217057 Q8R2Y8
Rat PTRH2 PTRH2 287593  
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Top Peptidyl-tRNA Hydrolase 2 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,227.50
Details
Yeast Yeast His tag   1 mg Log in to see 60 to 71 Days
$2,509.83
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$4,009.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$467.86
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

PTRH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced Peptidyl-tRNA Hydrolase 2 Proteins

  1. Human PTRH2 Protein expressed in Escherichia coli (E. coli) - ABIN667850 : De Pereda, Waas, Jan, Ruoslahti, Schimmel, Pascual: Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for 667850

More Proteins for Peptidyl-tRNA Hydrolase 2 (PTRH2) Interaction Partners

Human Peptidyl-tRNA Hydrolase 2 (PTRH2) interaction partners

  1. Bcl-2 (show BCL2 Proteins) expression patterns in various differentiated esophageal squamous cell carcinoma were higher than those in corresponding normal esophageal tissues with no statistical differences ( p > 0.05). Importantly, Bit1 expression was positively correlated with both matrix metalloproteinase 2 (show MMP2 Proteins) and Bcl-2 (show BCL2 Proteins) expression in esophageal squamous cell carcinoma and esophageal adenocarcinoma tissues ( p < 0.05).

  2. Our data establishes a PTRH2 mutation as a n (show DMD Proteins)ovel driver of (show DMD Proteins) congenital muscle degeneration and identifies a potential novel target to treat muscle (show DMD Proteins) myopathies.

  3. Bit1 may be an important regulator in cell growth, apoptosis, migration and invasion of esophageal squamous cell carcinoma via targeting FAK (show PTK2 Proteins)-paxillin (show PXN Proteins) pathway.

  4. these findings suggest a tumor suppressive role of the caspase-independent anoikis effector Bit1 in lung cancer.

  5. Reduction of the Bit1 level in cytosol, regulated by E2 binding to ESR1 (show ESR1 Proteins), was mainly mediated through PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathways.

  6. Bit1 plays pivotal roles in the development and progression of ESCC, and its biological functions in ESCC may be closely associated with AIF (show AIFM1 Proteins) and Bcl-2 (show BCL2 Proteins) levels.

  7. TLE1 (show TLE1 Proteins) inhibits the Bit1 anoikis pathway by reducing the formation of the proapoptotic Bit1-AES (show AES Proteins) complex in part through sequestration of AES (show AES Proteins) in the nucleus.

  8. Bit1 may be a useful pathological marker and a prognostic marker for serous papillary adenocarcinomas outcome.

  9. Data indicate that the cell death domain (CDD) to the N-terminal 62 amino acids of Bit1 was more potent in killing cells than the full-length Bit1 protein when equivalent amounts of cDNA were transfected.

  10. downregulation of Bit1 conferred cancer cells with enhanced anoikis resistance, adhesive and migratory properties in vitro

Mouse (Murine) Peptidyl-tRNA Hydrolase 2 (PTRH2) interaction partners

  1. Ptrh2 levels were up-regulated in dystrophin (show DMD Proteins) deficient mdx (show DMD Proteins) muscle, which correlates with the elevated levels of the a7b1 integrin observed in mdx (show DMD Proteins) muscle and Duchenne muscular dystrophy (show DMD Proteins) patients. Similar to the a7 integrin, Ptrh2 expression was decreased in laminin-a2 null gastrocnemius muscle

  2. These results support an unanticipated yet essential role for Bit-1 in controlling myogenesis through regulation of Bcl-2 (show BCL2 Proteins).

  3. downregulation of Bit1 specifically potentiated tumor metastasis in vivo

  4. Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathway

  5. These studies establish the physiological significance of Bit1 activity and begin to delineate a Bit1 signaling pathway that acts through Erk (show EPHB2 Proteins) regulation.

Peptidyl-tRNA Hydrolase 2 (PTRH2) Protein Profile

Protein Summary

The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity).

Gene names and symbols associated with PTRH2

  • peptidyl-tRNA hydrolase 2 (ptrh2)
  • peptidyl-tRNA hydrolase 2 (CC1G_10259)
  • peptidyl-tRNA hydrolase 2 (ANI_1_1036184)
  • peptidyl-tRNA hydrolase 2 (AOR_1_2082154)
  • peptidyl-tRNA hydrolase 2 (PTRH2)
  • peptidyl-tRNA hydrolase 2 (Ptrh2)
  • A230072I16Rik protein
  • Bit1 protein
  • CGI-147 protein
  • PTH2 protein
  • RGD1306819 protein
  • wu:fj09f02 protein
  • zgc:109954 protein

Protein level used designations for PTRH2

peptidyl-tRNA hydrolase 2 , PTH 2 , bcl-2 inhibitor of transcription 1 , peptidyl-tRNA hydrolase 2, mitochondrial , Bcl-2 inhibitor of transcription

GENE ID SPECIES
549411 Xenopus (Silurana) tropicalis
6005013 Coprinopsis cinerea okayama7130
4991038 Aspergillus niger CBS 513.88
5992240 Aspergillus oryzae RIB40
51651 Homo sapiens
217057 Mus musculus
791795 Danio rerio
417634 Gallus gallus
100682594 Canis lupus familiaris
516595 Bos taurus
287593 Rattus norvegicus
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