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Perilipin 2 Proteins (PLIN2)

The protein encoded by PLIN2 belongs to the perilipin family, members of which coat intracellular lipid storage droplets. Additionally we are shipping PLIN2 Antibodies (122) and PLIN2 Kits (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLIN2 123 Q99541
PLIN2 11520 P43883
Rat PLIN2 PLIN2 298199  
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Top PLIN2 Proteins at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$855.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,259.67
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,287.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$5,958.75
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$6,649.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

PLIN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Perilipin 2 (PLIN2) Interaction Partners

Human Perilipin 2 (PLIN2) interaction partners

  1. Conserved amphipathic helices mediate lipid droplet targeting of PLIN1 (show PLIN1 Proteins), PLIN2, and PLIN3 (show PLIN3 Proteins).

  2. In hepatitis C virus -infected human livers, occludin (show OCLN Proteins) and ADRP mRNA expression levels correlated with each other. Hepatitis C virus increases occludin (show OCLN Proteins) expression via the upregulation of ADRP.

  3. PLIN2 involves lipid modulation of GSK3 activity, GSK3 substrate expression, and cell growth/survival.

  4. PLIN2 inhibits insulininduced glucose uptake by activating NLRP3 (show NLRP3 Proteins), caspase1 (show CASP1 Proteins) and IL1beta (show IL1B Proteins), leading to a decreased IRS1 (show IRS1 Proteins) expression.

  5. Plin2 appears to be associated with functional alterations of the muscle

  6. Results demonstrate the clinical utility, specificity, and sensitivity of urine AQP1 (show AQP1 Proteins) and PLIN2 to diagnose renal cell carcinoma (show MOK Proteins).

  7. Postprandial triglyceride rich lipoproteins may be involved in atherosclerotic plaque formation through the regulation of perilipin-2 and perilipin-3 (show PLIN3 Proteins) proteins in macrophages.

  8. Immunohistochemical distinction of renal cell carcinoma (show MOK Proteins) from other carcinomas with clear-cell histomorphology: utility of CD10 (show MME Proteins) and CA-125 (show MUC16 Proteins) in addition to PAX-2 (show PAX2 Proteins), PAX-8 (show PAX8 Proteins), RCCma, and adipophilin.

  9. ADRP was detectable in human BM during the whole 12 months of lactation period and its levels were intraindividually well-conserved.

  10. Perilipin 2 binding to the lipid droplet surface requires both hydrophobic and electrostatic interactions.

Cow (Bovine) Perilipin 2 (PLIN2) interaction partners

  1. These results demonstrate that bovine embryos at the blastocyst stage expressed ADRP mRNA and protein, and that the embryonic culture system modified this expression.

  2. Adipophilin and TIP47 (show PLIN3 Proteins) are expressed in lipid droplets of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes.

  3. 25 novel polymorphisms were identified within all exons and their flanking regions of ADFP, including the promoter region.

Mouse (Murine) Perilipin 2 (PLIN2) interaction partners

  1. PLIN2 involves lipid modulation of GSK3 activity, GSK3 substrate expression, and cell growth/survival.

  2. Plin2 modulates rapid effects of diet on fecal lipid levels, enterocyte CLD (show LMF1 Proteins) contents, and fuel utilization properties of mice that correlate with structural and functional differences in their gut (show GUSB Proteins) microbial communities

  3. Postprandial triglyceride rich lipoproteins may be involved in atherosclerotic plaque formation through the regulation of perilipin-2 and perilipin-3 (show PLIN3 Proteins) proteins in macrophages.

  4. flavonoids from Coreopsis tinctoria extracts can reduce blood lipid without liver function damage by down-regulating ADRP.

  5. The structure and function of specific domains responsible for Plin2-lipid interactions were identified.

  6. Plin2 has a critical pathogenic role in experimental alcoholic liver disease

  7. PLIN2-mediated lipid accumulation and utilization by the liver is important for efficient liver regeneration in response to partial hepatectomy and toxic liver injury.

  8. Together, our findings suggest that WAY, an FXR (show NR1H4 Proteins) agonist, attenuates liver steatosis through multiple mechanisms critically involved in the development of hepatosteatosis.

  9. Collectively these data suggest that whereas perilipin 1 (show PLIN1 Proteins) potently suppresses basal lipolysis in adipocytes, perilipins 2 and 3 facilitate higher rates of basal lipolysis

  10. metformin prevents hepatic steatosis by regulating the expression of ADRP

Pig (Porcine) Perilipin 2 (PLIN2) interaction partners

  1. These findings suggested that PLIN2 was a major lipid droplet-associated protein (show PLIN1 Proteins) in porcine oocytes.

  2. In pig muscle PLIN1 (show PLIN1 Proteins) and PLIN2 proteins are localized in correspondence with extra and intra-myocellular lipids, respectively.

  3. PLIN2 can be a marker for carcass quality in pigs.

PLIN2 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with Perilipin 2 Proteins (PLIN2)

  • perilipin 2 (plin2)
  • adipophilin (LOC100304704)
  • Adipophilin (adfp)
  • perilipin 2 (PLIN2)
  • perilipin 2 (Plin2)
  • AA407157 protein
  • Adfp protein
  • adipophilin protein
  • ADPH protein
  • Adrp protein
  • DKFZp469F1012 protein
  • fatvg protein
  • MGC76047 protein
  • perilipin-2 protein
  • PLIN2 protein

Protein level used designations for Perilipin 2 Proteins (PLIN2)

perilipin 2 , adipose differentiation-related protein , adipophilin , Adipophilin , perilipin-2 , ADRP , adipose differentiation related protein , adipocyte differentiation-related protein

GENE ID SPECIES
394560 Xenopus (Silurana) tropicalis
398143 Xenopus laevis
100304704 Ictalurus punctatus
100380740 Salmo salar
465012 Pan troglodytes
100172891 Pongo abelii
100016609 Monodelphis domestica
123 Homo sapiens
280981 Bos taurus
11520 Mus musculus
298199 Rattus norvegicus
100338869 Oryctolagus cuniculus
397402 Sus scrofa
100861245 Capra hircus
474720 Canis lupus familiaris
427237 Gallus gallus
100125354 Ovis aries
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