anti-Peripheral Myelin Protein 22 (PMP22) Antibodies

PMP22 encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Additionally we are shipping PMP22 Kits (27) and PMP22 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PMP22 5376 Q01453
PMP22 24660 P25094
PMP22 18858 P16646
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Top anti-PMP22 Antibodies at antibodies-online.com

Showing 10 out of 98 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), IHC, WB Staining of PMP22 (brown) in dorsal root ganglion and spinal roots in 20 week fetal spinal cord preparation from rhesus monkey. 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PMP22 Antibody  in Human normal Uterus cell line lysates (35ug/lane). This demonstrates the PMP22 antibody detected the PMP22 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$467.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PMP22 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-PMP22 Polyclonal Antibody, Unconjugated (ABIN726680) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat spinal cord labeled with Anti-PMP22 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from MDA-MB-435 cells, using PMP22 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PMP22 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry analyzes of GAS3 antibody in paraffin-embedded human brain tissue. Western blot analysis of GAS3 antibody in extracts from MDA-MB-435 cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated WB PMP22 Antibody  western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the PMP22 antibody detected the PMP22 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

PMP22 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PMP22 Antibodies

  1. Human Polyclonal PMP22 Primary Antibody for EIA, WB - ABIN954219 : Kohl, Fischer, Groh, Wessig, Martini: MCP-1/CCL2 modifies axon properties in a PMP22-overexpressing mouse model for Charcot-Marie-tooth 1A neuropathy. in The American journal of pathology 2010 (PubMed)
    Show all 5 references for 954219

  2. Human Monoclonal PMP22 Primary Antibody for IHC (p), IHC - ABIN258611 : Gregson, Zhang, Pritchard, Wang, Sanvito, Hayday, Hughes: Characterization of a monoclonal antibody specific for human peripheral myelin protein 22 and its use in immunohistochemical studies of the fetal and adult nervous system. in Journal of the peripheral nervous system : JPNS 2007 (PubMed)

More Antibodies against PMP22 Interaction Partners

Zebrafish Peripheral Myelin Protein 22 (PMP22) interaction partners

  1. The results of this study indicated that an adequate pmp22 transcription level is necessary for correct myelination of jawed vertebrates.

Human Peripheral Myelin Protein 22 (PMP22) interaction partners

  1. Exome sequencing identified MFN2 (show MFN2 Antibodies) SNVs in two of the individuals. Neuropathy-associated CNV outside of the PMP22 locus is rare in Charcot-Marie-Tooth (CMT) disease . Nevertheless, there is potential clinical utility in testing for CNVs and exome sequencing in CMT cases negative for the CMT1A duplication.

  2. We discovered that Tead1 (show TEAD1 Antibodies) and co-activators Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) are required for Pmp22 expression, as well as for the expression of Egr2 (show EGR2 Antibodies) Tead1 (show TEAD1 Antibodies) directly binds Pmp22 and Egr2 (show EGR2 Antibodies) enhancers early in development and Tead1 (show TEAD1 Antibodies) binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 (show TEAD1 Antibodies) as a novel regulator of Pmp22 expression during development in concert with Sox10 (show SOX10 Antibodies) and Egr2 (show EGR2 Antibodies)

  3. This study demonstrated We show that blink (show TGFb Antibodies) reflex studies are reliable for identification of inherited demyelinating polyneuropathy (with pmp22 mutation) regardless of severity and can facilitate algorithmic decisions in genetic testing.

  4. Findings suggest that miR (show MLXIP Antibodies)-200bc/429 inhibit OS cells proliferation and invasion by targeting PMP22, and function as a tumor suppressor.

  5. PMP22 deletion leads to functional, metabolic and macro-structural alterations in the afferent visual system of hereditary neuropathy with liability to pressure palsies patients.

  6. we report molecular and clinical characterizations of six subjects with the reciprocal phenomenon of deletions spanning both genes, i.e., PMP22-RAI1 (show DOM3Z Antibodies) deletions. Systematic clinical studies revealed features consistent with SMS (show SMS Antibodies), including features of intellectual disability, speech and gross motor delays, behavioral problems and ocular abnormalities.

  7. Data suggest that the father has carried the same duplication of the peripheral myelin protein 22 (PMP22) gene but with no detectable symptom may be due to irregular transmission pattern of the mutation.

  8. our data suggest that an alteration of mRNA processing could be a pathogenic mechanism in CMT1A.

  9. Data (including data from studies using recombinant proteins that lack typical in-vivo post-translational modifications such as palmitoylation) suggest PMP22 exhibits little tendency to partition into liquid-ordered domains of unilamellar vesicles.

  10. PMP22 gene knockdown inhibited progression of Chronic Myeloid Leukemia (show BCL11A Antibodies).

Mouse (Murine) Peripheral Myelin Protein 22 (PMP22) interaction partners

  1. We discovered that Tead1 (show TEAD1 Antibodies) and co-activators Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) are required for Pmp22 expression, as well as for the expression of Egr2 (show EGR2 Antibodies) Tead1 (show TEAD1 Antibodies) directly binds Pmp22 and Egr2 (show EGR2 Antibodies) enhancers early in development and Tead1 (show TEAD1 Antibodies) binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 (show TEAD1 Antibodies) as a novel regulator of Pmp22 expression during development in concert with Sox10 (show SOX10 Antibodies) and Egr2 (show EGR2 Antibodies)

  2. The basal lamina and PMP22 act in concert to contribute to a resilience and integrity of peripheral nerves at the single fibre level.

  3. A role was identified for PMP22 in the linkage of the actin cytoskeleton with the plasma membrane.

  4. This study demonistrated that Paranodal dysmyelination in peripheral nerves of Trembler mice.

  5. This study showed that a number of ongoing pathogenic mechanisms contribute to the progression of the neuropathy in C22 mice, which initiates with abnormal expression of PMP22.

  6. Pxmp2 in the mammary fat pad is plays a critical role in stromal lipid homeostasis and in development of mammary gland epithelium in mice

  7. This study revealed a novel mechanism by which PMP22 deficiency affects nerve conduction not through removal of myelin, but through disruption of myelin junctions

  8. This study showed that mouse PMP22 is palmitoylated at C85 and mutating C85S abolishes PMP22 palmitoylation.

  9. Peripheral myelin protein 22 (PMP22) performs distinct actions on the formation, maturation, degeneration and regeneration of sciatic nerve myelin sheath.

  10. Egr2 (show EGR2 Antibodies) and Sox10 (show SOX10 Antibodies) activity are directly involved in mediating the developmental induction of Pmp22 expression through an intronic enhancer.

PMP22 Antigen Profile

Protein Summary

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein.

Gene names and symbols associated with PMP22

  • peripheral myelin protein 22a (pmp22a) antibody
  • peripheral myelin protein 22 (PMP22) antibody
  • peripheral myelin protein 22 (pmp22) antibody
  • peripheral myelin protein 22 (Pmp22) antibody
  • peroxisomal membrane protein 2 (Pxmp2) antibody
  • 22kDa antibody
  • CMT1A antibody
  • CMT1E antibody
  • DSS antibody
  • Gas-3 antibody
  • HMSNIA antibody
  • HNPP antibody
  • MGC69407 antibody
  • MGC80653 antibody
  • PMP22 antibody
  • Sp110 antibody
  • Tr antibody
  • trembler antibody
  • wu:fa04d03 antibody
  • wu:fa08d03 antibody

Protein level used designations for PMP22

peripheral myelin protein 22 , growth arrest-specific protein 3 , PMP-22 , SAG , SR13 myelin protein , schwann cell membrane glycoprotein , peripheral myelin protein, 22 kDa , PAS positive glycoprotein , PASII , 22 kDa peroxisomal membrane protein , peroxisomal membrane protein 2, 22 kDa

GENE ID SPECIES
334817 Danio rerio
417327 Gallus gallus
446837 Xenopus laevis
479509 Canis lupus familiaris
594946 Xenopus (Silurana) tropicalis
100302348 Ovis aries
5376 Homo sapiens
24660 Rattus norvegicus
18858 Mus musculus
534497 Bos taurus
100034146 Equus caballus
693527 Macaca mulatta
744977 Pan troglodytes
100172535 Pongo abelii
19301 Mus musculus
Selected quality suppliers for anti-PMP22 (PMP22) Antibodies
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