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anti-Phenylethanolamine N-Methyltransferase (PNMT) Antibodies

The product of PNMT catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). Additionally we are shipping PNMT Proteins (14) and PNMT Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PNMT 5409 P11086
PNMT 24661 P10937
PNMT 18948 P40935
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Top anti-PNMT Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$407.00
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC206586 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PNMT antibody (ABIN2454519), and then analyzed by flow cytometry. Anti-PNMT mouse monoclonal antibody (ABIN2454519) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PNMT (RC206586). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-PNMT mouse monoclonal antibody (ABIN2454520) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PNMT (RC206586). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PNMT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PNMT. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-PNMT mouse monoclonal antibody (ABIN2454540) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PNMT (RC206586). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PNMT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PNMT. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-PNMT mouse monoclonal antibody (ABIN2454516) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PNMT (RC206586). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PNMT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PNMT. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Cow Guinea Pig Un-conjugated IHC (fro), IHC (p)   50 μL Log in to see 6 to 8 Days
$478.50
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$493.17
Details

PNMT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PNMT Antibodies

  1. Cow (Bovine) Polyclonal PNMT Primary Antibody for IHC (fro), IHC (p) - ABIN115760 : Bjartell, Persson, Absood, Sundler, Håkanson: Helodermin-like peptides in noradrenaline cells of adrenal medulla. in Regulatory peptides 1989 (PubMed)

  2. Human Monoclonal PNMT Primary Antibody for EIA, WB - ABIN954226 : Huang, Zhang, Hu, Ma, Yang: Phenylethanolamine N-methyltransferase gene promoter haplotypes and risk of essential hypertension. in American journal of hypertension 2011 (PubMed)

More Antibodies against PNMT Interaction Partners

Cow (Bovine) Phenylethanolamine N-Methyltransferase (PNMT) interaction partners

  1. Nicotinic stimuli appear to regulate expression of the epinephrine-synthesizing gene PNMT through a previously uncharacterized regulatory element.

  2. PNMT gene is located within human chromosome 17q12 amplicon, including PPP1R1B (show PPP1R1B Antibodies), STARD3 (show STARD3 Antibodies), TCAP (show TCAP Antibodies), PNMT, ERBB2 (show ERBB2 Antibodies), MGC14832 and GRB7 (show GRB7 Antibodies) genes. PPP1R1B (show PPP1R1B Antibodies) ~ ERBB2 (show ERBB2 Antibodies) ~ GRB7 (show GRB7 Antibodies) locus is amplified in human gastric cancer and breast cancer.

Human Phenylethanolamine N-Methyltransferase (PNMT) interaction partners

  1. initial velocity studies on human PNMT in the absence and presence of product and dead end (show DND1 Antibodies) inhibitors.

  2. The 2-SNP AA haplotype in the PNMT promoter is associated with decreased risk of essential hypertension in Han Chinese.

  3. PNMT G-390A polymorphism is possibly associated with essential hypertension risk in male Chinese Han population.

  4. In Caucasians, phenylethanolamine N-methyltransferase single nucleotide polymorphisms are associated with the development of acute kidney injury, disease severity, and in-hospital mortality.

  5. PNMT variants in cis (show CISH Antibodies) may interact with nuclear factors in trans to govern adrenergic activity.

  6. Human PNMT has been crystallized in complex with an inhibitor and the cofactor product S-adenosyl-L-homocysteine and diffraction data measured from a cryocooled crystal extend to a resolution of 2.3 A.

  7. Association between the phenylethanolamine N-methyltransferase gene and multiple sclerosis.

  8. homozygosity/heterozygosity of the phenylethanolamine N-methyltransferase gene polymorphism was highly predictive of significant weight loss with sibutramine during the first 3 months of obesity treatment

  9. genetic variants of PNMT may play a role in the development of essential hypertension.

  10. Presence of local PNMT transcription in human heart after transplantation.

Mouse (Murine) Phenylethanolamine N-Methyltransferase (PNMT) interaction partners

  1. Data suggest that Pnmt plays role in fear response and startle reactivity; compared with wild-type mice, Pnmt-knockout mice exhibit reduced contextual fear but normal cued fear.

  2. Although temperature was normal in Pnmt(-/-) mice, the brown fat response to cold was abnormal with no increase in Ucp-1 (show UCP1 Antibodies) or Pgc-1alpha (show PPARGC1A Antibodies) mRNA levels (but with an exaggerated cold-induced lipid loss from the tissue).

  3. surprisingly high levels of the epinephrine synthesizing enzyme phenylethanolamine N-methyl transferase (PNMT) were detected in the thymus of young mice.

  4. A truncated mouse phenylethanolamine N-methyltransferase splice variant has dominant-negative activity

  5. PNMT expression is regulated late in mouse gestation by AP2-alpha (show TFAP2A Antibodies) and glucocorticoids

  6. clear, significant increase in aggression arising from PNMT overexpression

  7. Regulation of the PNMT gene expression in various compartments of heart includes both corticosterone-dependent and independent mechanisms.

  8. Transcriptional suppression by cAMP as a mechanism for regulating PNMT expression in both normal and neoplastic mouse chromaffin cells.

  9. Neuronal nitric oxide synthase (show NOS1 Antibodies) gene inactivation reduces the expression of vasopressin (show AVP Antibodies) in the hypothalamic paraventricular nucleus and of PNMT in the adrenal gland of the mouse.

PNMT Antigen Profile

Protein Summary

The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with PNMT

  • phenylethanolamine N-methyltransferase (PNMT) antibody
  • phenylethanolamine-N-methyltransferase (Pnmt) antibody
  • Pent antibody
  • PNMT antibody
  • PNMTase antibody

Protein level used designations for PNMT

phenylethanolamine N-methyltransferase , PNMTase , noradrenaline N-methyltransferase , phenylethanolamine N-methylase

GENE ID SPECIES
100033859 Equus caballus
454634 Pan troglodytes
697444 Macaca mulatta
776803 Gallus gallus
281413 Bos taurus
5409 Homo sapiens
491023 Canis lupus familiaris
100144479 Sus scrofa
24661 Rattus norvegicus
18948 Mus musculus
Selected quality suppliers for anti-PNMT (PNMT) Antibodies
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