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anti-Phospholipase A2 (YWHAZ) Antibodies

Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. Additionally we are shipping YWHAZ Proteins (35) and YWHAZ Kits (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
YWHAZ 5319 P04054
YWHAZ 18778 Q9Z0Y2
YWHAZ 29526 P04055
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Top anti-YWHAZ Antibodies at antibodies-online.com

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN238555 (0.01µg/ml) staining of Human Pancreas lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: HeLa 15% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of PLA2G1B Antibody (C-term) (ABIN651072) in mouse spleen tissue lysates (35 µg/lane). PLA2G1B (arrow) was detected using the purified polyclonal antibody. Western blot analysis of PLA2G1B (arrow) using rabbit polyclonal PLA2G1B Antibody (C-term) (ABIN651072). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PLA2G1B gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
REACT_Bee Rabbit Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Log in to see 6 to 8 Days
$412.50
Details
Pig Rabbit Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$218.90
Details

YWHAZ Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine) ,

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Rat (Rattus)


Top referenced anti-YWHAZ Antibodies

  1. Mouse (Murine) Polyclonal YWHAZ Primary Antibody for ELISA - ABIN2000787 : Labonté, Kirby, Schildmeyer, Cannon, Huggins, Hui: Group 1B phospholipase A2-mediated lysophospholipid absorption directly contributes to postprandial hyperglycemia. in Diabetes 2006 (PubMed)
    Show all 2 references for ABIN2000787

  2. Human Polyclonal YWHAZ Primary Antibody for ELISA, WB - ABIN238555 : Kolko, Christoffersen, Varoqui, Bazan: Expression and induction of secretory phospholipase A2 group IB in brain. in Cellular and molecular neurobiology 2006 (PubMed)

More Antibodies against YWHAZ Interaction Partners

Fruit Fly (Drosophila melanogaster) Phospholipase A2 (YWHAZ) interaction partners

Human Phospholipase A2 (YWHAZ) interaction partners

  1. The sPLA2 (show PLA2G2A Antibodies) IB-PLA2R (show PLA2R1 Antibodies) interaction stimulated podocyte apoptosis through activating ERK1/2 (show MAPK1/3 Antibodies) and cPLA2alpha (show PLA2G4A Antibodies) and through increasing the podocyte AA content

  2. TNF-alpha (show TNF Antibodies)-induced cPLA2 (show PLA2G4A Antibodies) expression and PGE2 release were mediated through a Jak2 (show JAK2 Antibodies)/PDGFR (show PDGFRB Antibodies)/PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/p42/p44 (show PSMC6 Antibodies) MAPK (show MAPK3 Antibodies)/Elk-1 (show ELK1 Antibodies) pathway in human lung epithelial cells.

  3. stimulation of three isoforms of PLA2 by thapsigargin liberates free AA that, in turn, induces capacitative calcium influx in human T-cells

  4. results indicate a selective sorting of a cell-derived cPLA2 (show PLA2G4A Antibodies) during human cytomegalovirus maturation, which is further required for infectivity

  5. Group IB phospholipase A2 (PLA2G1B) stimulates leukotriene B4 (LTB4 (show PTGR1 Antibodies)) production in the absence of cytochalasin B in human neutrophils.

  6. Here, we report sPLA2 (show PLA2G2A Antibodies)-IB in rat and human brain as well as in neurons in primary culture. The distribution of sPLA2 (show PLA2G2A Antibodies)-IB seems to be mainly neuronal, with the highest abundance occurring in the cerebral cortex and hippocampus.

  7. a critical regulatory role of arachidonate reacylation that limits leukotriene biosynthesis in concert with 5-lipoxygenase (show ALOX5 Antibodies) and cytosolic phospholipase A (show HRASLS Antibodies)(2)alpha activation

  8. Results describe the structural basis for bile salt inhibition of pancreatic phospholipase A2.

  9. MMP-2 (show MMP2 Antibodies)/9 production is regulated by sPLA2 (show PLA2G2A Antibodies)-IB acting as a receptor ligand to activate cPLA2 (show PLA2G4A Antibodies)

Pig (Porcine) Phospholipase A2 (YWHAZ) interaction partners

  1. Equilibrium unfolding of porcine pancreatic phospholipase A2 was monitored using multiple approaches. An unusually broad unfolding transition at remarkably high denaturant concentration was observed.

  2. Porcine group IB secretory phospholipase A2 (PLA2G1B) stimulates the expression and secretion of CXC chemokine (show CXCL12 Antibodies) ligand 8 (show CCL8 Antibodies) (CXCL8 (show IL8 Antibodies)) in human neutrophils without affecting other proinflammatory cytokines.

  3. Porcine pancreatic PLA(2) shows a long lag (show STMN1 Antibodies) phase of several hours during which the enzyme binds to the bilayer surface, but only 5+/-3% of the lipids react before the onset of rapid hydrolysis.

  4. Results describe the structural basis for bile salt inhibition of pancreatic phospholipase A2.

  5. MMP-2 (show MMP2 Antibodies)/9 production is regulated by sPLA2 (show PLA2G2A Antibodies)-IB acting as a receptor ligand to activate cPLA2 (show PLA2G4A Antibodies)

  6. Results show that the decylsulfate epitope for the successive E i (#) complexes increasingly resembles the micellar complex formed by the binding of PLA2 to preformed micelles.

  7. An increased sPLA(2 (show PLA2G2A Antibodies)) activity and a reduced inhibition may play an important role in the pathogenesis of ischemia-reperfusion injury of non-heart-beating donor liver grafts.

  8. Interfacial activation of pig pancreatic IB phospholipase A (show HRASLS Antibodies)(2) (PLA2) is modeled in terms of the three discrete premicellar complexes (E(i)(#), i = 1, 2, or 3) consecutively formed by the cooperative binding of a monodisperse amphiphile to the i-face

Cow (Bovine) Phospholipase A2 (YWHAZ) interaction partners

  1. Phospholipase A2 isoforms are differentially regulated; they selectively participate in retinal signaling in an experimental model of age-related macular degeneration.

  2. results suggest the hydrophobic surfactant protein, SP-B, protects alveolar surfactant phospholiopids from hydrolysis mediated by multiple sPLA(2 (show PLA2G2A Antibodies)) in both vesicles (alveolar subphase) and monomolecular films (air-liquid interface)

  3. crystal structure of the triple mutant pancreatic phospholipase A2 with calcium.

  4. NMR characterization of a unique low-barrier hydrogen bond between an active site residue from the enzyme and a bound inhibitor: the complex between secreted phospholipase A (show HRASLS Antibodies)(2) (sPLA(2 (show PLA2G2A Antibodies)), from bovine pancreas) and a transition-state analog inhibitor HK32

  5. The final protein model consists of 123 amino-acid residues, two calcium ions, one chloride ion, 243 water molecules and six 2 (show SIX2 Antibodies)-methyl-2,4-pentanediol molecules.

  6. The crystal structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2 complexed with an organic molecule, p-methoxybenzoic acid (anisic acid), is reported.

  7. The quadruple mutant of phospholipase A2 has monoclinic or trigonal crystal structures and results suggested evidence for the involvement of the second calcium and surface loop in interfacial binding.

Mouse (Murine) Phospholipase A2 (YWHAZ) interaction partners

  1. Pla2g1b inactivation suppressed diet-induced body weight gain and reduced diabetes and atherosclerosis in LDL receptor (show LDLR Antibodies)-deficient mice.

  2. inhibition of Pla2g1b protects against diet-induced hyperlipidemia

  3. Lysophospholipids produced by Pla2g1b hydrolysis suppress hepatic fat utilization and down-regulate energy expenditure, preventing metabolically beneficial adaptation to a high-fat diet exposure in promoting diet-induced obesity and type 2 diabetes.

  4. sPLA2IB has a role in promoting MMP-2 (show MMP2 Antibodies) mediated cell migration via the phosphatidylinositol 3-kinase and Akt (show AKT1 Antibodies) pathway

  5. Elevating plasma lysophospholipid levels in Pla2g1b deficient mice via intraperitoneal injection resulted in glucose intolerance.

  6. pro-inflammatory effects of Ps. aeruginosa involve release of an sPLA2 of epithelial origin that, in part, via distinct signalling molecules, transactivates the ABCA1 gene, leading to export of phospholipid.

Horse (Equine) Phospholipase A2 (YWHAZ) interaction partners

  1. The results indicate that PLA2 activity in equine endometrium changes with the stage of the oestrous cycle and thus may be influenced by systemic hormone concentrations.

  2. During pregnancy, PLA2 expression may be sufficient to initiate the cascade for prostaglandin f2alpha secretion and does not play a direct role in maternal recognition of pregnancy.

YWHAZ Antigen Profile

Protein Summary

Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986

Gene names and symbols associated with YWHAZ

  • CG42237 gene product from transcript CG42237-RA (CG42237) antibody
  • phospholipase A2 (PLA2) antibody
  • phospholipase A2 (Pla2) antibody
  • phospholipase A2, group IB (pancreas) (PLA2G1B) antibody
  • phospholipase A2, group IB (pancreas) (Pla2g1b) antibody
  • phospholipase A2, group IB, pancreas (Pla2g1b) antibody
  • phospholipase A2, group IVA (cytosolic, calcium-dependent) (PLA2G4A) antibody
  • bvPLA2 antibody
  • C133 antibody
  • CG4346 antibody
  • Dmel\\CG42237 antibody
  • Dmel_CG4346 antibody
  • GB13351 antibody
  • PLA2 antibody
  • Pla2a antibody
  • PLA2G1B antibody
  • PPLA2 antibody
  • sPLA(2)-IB antibody
  • sPLA2IB antibody

Protein level used designations for YWHAZ

CG42237-PA , phospholipase A2 , allergen Api m 1 , allergen Api m I , phosphatidylcholine 2-acylhydrolase , phosphatidylcholine 2-acylhydrolase 1B , group IB phospholipase A2 , group IB secretory phospholipase A(2) , phospholipase A2, major isoenzyme , Group IB phospholipase A2 , Phosphatidylcholine 2-acylhydrolase 1B , phospholipase A2, group IB, pancreas , PLA2-Ib , phospholipase A2 group IB , phospholipase A2, group 1B , cPLA2 , cytosolic phospholipase A2 , phospholipase A2 group IVA , phospholipase A2, group IB (pancreas)

GENE ID SPECIES
32261 Drosophila melanogaster
5725622 Chlamydomonas reinhardtii
100631065 Bombus terrestris
406141 Apis mellifera
5319 Homo sapiens
404011 Canis lupus familiaris
445525 Sus scrofa
100732984 Cavia porcellus
282457 Bos taurus
101117700 Ovis aries
18778 Mus musculus
29526 Rattus norvegicus
100033889 Equus caballus
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