You are viewing an incomplete version of our website. Please click to reload the website as full version.

Phosphotylinosital 3 Kinase Proteins (PI3K)

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Additionally we are shipping Phosphotylinosital 3 Kinase Kits (30) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse PI3K PI3K 18708 P26450
PI3K    
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Phosphotylinosital 3 Kinase Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$4,173.75
Details
HOST_Baculovirus infected Insect Cells Human His tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 3 to 4 Days
$534.64
Details

PI3K Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Phosphotylinosital 3 Kinase (PI3K) Interaction Partners

Mouse (Murine) Phosphotylinosital 3 Kinase (PI3K) interaction partners

  1. Uncarboxylated osteocalcin (show BGLAP Proteins) inhibits high glucose-induced reactive oxygen species production and stimulates osteoblastic differentiation by inhibiting the activation of PI3K/Akt (show AKT1 Proteins) in MC3T3-E1 cells.

  2. miR-130a plays a critical role in attenuation of cardiac dysfunction and remodeling after myocardial infarction. The mechanisms involve activation of PI3K/Akt signaling via suppression of PTEN expression.

  3. PI3K/AKT (show AKT1 Proteins) pathway was partially involved in the modulation of the release HMGB-1 (show HMGB1 Proteins) from reactive astrocytes.

  4. These data demonstrate the ability of this heterozygous mutation to alter PI3K activity in vivo and the central role of PI3K in insulin (show INS Proteins)/growth factor action, adipocyte function, and glucose metabolism.

  5. These results suggested that cordycein is a highly selective treatment to induce MA-10 cells apoptosis via p38 (show CRK Proteins) MAPKs signaling.

  6. A Cytosolic Multiprotein Complex Containing p85alpha Is Required for beta-Catenin (show CTNNB1 Proteins) Activation in Colitis and Colitis-associated Cancer.

  7. Our results thus demonstrated that GalT (show GALT Proteins) deficiency can effect down-regulation of the PI3K/Akt (show AKT1 Proteins) growth signaling pathway in mouse fibroblasts through distinct mechanisms targeting both gene and protein expression levels.

  8. Our results indicate HDM (show HDAC3 Proteins) extract induced the expression of VEGF (show VEGFA Proteins), TGF-beta1 (show TGFB1 Proteins), and FGF-2 (show FGF2 Proteins) by activating the PI3K/Akt (show AKT1 Proteins)/HIF-1alpha (show HIF1A Proteins) pathway in human primary cultured NECs and in the nasal mucosa of a murine model.

  9. The target miRNAs are closely associated with dysregulation of insulin/PI3K-AKT signaling, suggesting that the Cmah-null mice could be a useful model for studying diabetes.

  10. Apelin (show APLN Proteins) regulates inflammatory response, diminishes inflammatory remote organ damage and improves survival in an experimental model of burn sepsis, which is at least partly mediated by a phosphatidylinositol 3-kinase/protein kinase B (show AKT1 Proteins) dependent pathway.

Phosphotylinosital 3 Kinase (PI3K) Protein Profile

Protein Summary

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (By similarity).

Gene names and symbols associated with PI3K

  • phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1)
  • AA414921 protein
  • C530050K14 protein
  • p50alpha protein
  • p55alpha protein
  • p85alpha protein
  • PI3K protein

Protein level used designations for PI3K

PI3-kinase regulatory subunit alpha , PI3-kinase subunit p85-alpha , PI3K regulatory subunit alpha , phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha , phosphatidylinositol 3-kinase regulatory subunit alpha , ptdIns-3-kinase regulatory subunit alpha , ptdIns-3-kinase regulatory subunit p85-alpha

GENE ID SPECIES
18708 Mus musculus
Selected quality suppliers for Phosphotylinosital 3 Kinase Proteins (PI3K)
Did you look for something else?