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Pirin Proteins (PIR)

PIR encodes a member of the cupin superfamily. Additionally we are shipping Pirin Antibodies (44) and Pirin Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PIR 69656 Q9D711
PIR 8544 O00625
PIR 363465 Q5M827
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Top Pirin Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 56 to 66 Days
$2,755.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,768.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PIR Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

Top referenced Pirin Proteins

  1. Human PIR Protein expressed in Escherichia coli (E. coli) - ABIN667677 : Gelbman, Heguy, OConnor, Zabner, Crystal: Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis. in Respiratory research 2007 (PubMed)
    Show all 2 references for ABIN667677

More Proteins for Pirin (PIR) Interaction Partners

Mouse (Murine) Pirin (PIR) interaction partners

  1. Sod1(-/-) mice have a significantly elevated level of Pir mRNA in the spleen and kidney but not in the liver, heart, or/and brain.

Arabidopsis thaliana Pirin (PIR) interaction partners

  1. PRN1 may play a critical role in cellular quercetin levels and influence light- or hormonal-directed early development.

  2. Arabidopsis mutants of the PRN1 gene, which is involved in abiotic and biotic signaling affecting phenylalanine-derived flavonoids, showed altered susceptibility to cryptoccocal infections, suggesting roles for this pathway in cryptococcal defense.

Human Pirin (PIR) interaction partners

  1. Pirin regulates E-cadherin (show CDH1 Proteins) independently of Bcl3 (show BCL3 Proteins)-Slug (show SNAI2 Proteins) signaling.

  2. The NRF2 transcription factor binds to this element in vivo and drives the basal PIR expression.

  3. Pirin is a newly identified binding partner of EAF2/U19 (show EAF2 Proteins) capable of down-regulating EAF2/U19 (show EAF2 Proteins) protein and alleviating its inhibition of prostate cancer cell survival/proliferation.

  4. Data indicate that the R-shaped area composes the interface for pirin-NF-kappaB (show NFKB1 Proteins) binding that is responsible for modulation of NF-kappaB's DNA-binding properties.

  5. pirin may have a relevant role in melanoma progression.

  6. knockdown of pirin or treatment with the small molecule inhibited melanoma cell migration

  7. This study aimed to examine genetic variations in the PIR gene by a comprehensive tagging method and its sex-specific effects on bone mineral density and osteoporotic risk.

  8. An abnormal pattern of PIR sub-cellular localization is a characteristic feature of a subset of melanomas, and suggest it may represent a marker associated with disease progression.

  9. Pirin downregulation is a feature of acute myeloid leukemia (show BCL11A Proteins) and leads to impairment of terminal myeloid differentiation.

  10. x-ray crystallography of of human pirin shows that it is an iron-binding nuclear protein and transcription cofactor

Pirin (PIR) Protein Profile

Protein Summary

This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with Pirin Proteins (PIR)

  • pirin-like protein (pirin)
  • pirin, quercetinase (pirin)
  • pirin (Pir)
  • pirin (pir)
  • pirin (LOC100350592)
  • pirin (PRN)
  • pirin (iron-binding nuclear protein) (PIR)
  • pirin (iron-binding nuclear protein) (Pir)
  • pirin (iron-binding nuclear protein) (pir)
  • pirin-like (LOC100514999)
  • 2310042L19Rik protein
  • ATPIRIN1 protein
  • pirin protein
  • Pirnl protein
  • PRN1 protein
  • xpir protein
  • zgc:92778 protein

Protein level used designations for Pirin Proteins (PIR)

pirin-like protein , pirin, quercetinase , iron-binding nuclear protein , pirin like , probable quercetin 2,3-dioxygenase PIR , probable quercetinase , pirin

GENE ID SPECIES
2772401 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
8435992 Acetobacter pasteurianus IFO 3283-01
8436236 Acetobacter pasteurianus IFO 3283-01
69656 Mus musculus
436823 Danio rerio
100350592 Oryctolagus cuniculus
825091 Arabidopsis thaliana
8544 Homo sapiens
480846 Canis lupus familiaris
790878 Bos taurus
363465 Rattus norvegicus
379306 Xenopus laevis
100713331 Cavia porcellus
100514999 Sus scrofa
Selected quality suppliers for Pirin Proteins (PIR)
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