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Plakophilin 1 Proteins (PKP1)

PKP1 encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Additionally we are shipping Plakophilin 1 Kits (32) and Plakophilin 1 Antibodies (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PKP1 18772 P97350
Rat PKP1 PKP1 304822  
PKP1 5317 Q13835
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Top Plakophilin 1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PKP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Plakophilin 1 (PKP1) Interaction Partners

Human Plakophilin 1 (PKP1) interaction partners

  1. These results implicate the participation of PKP1 in early tooth morphogenesis as an effector of canonical Wnt (show WNT2 Proteins) signaling that controls ameloblast differentiation via regulation of the cell adhesion complex

  2. Collectively, altered expression of PKP1 and SPOCK1 (show SPOCK1 Proteins) appears to be a frequent and critical event in prostate cancer

  3. cytoplasmic PKP1/3 are components of mRNA ribonucleoprotein particles and act as posttranscriptional regulators of gene expression.

  4. Plakophilin-1 has a role in protecting keratinocytes from pemphigus vulgaris (show DSG3 Proteins) IgG by forming calcium-independent desmosomes

  5. Data indicate that upon activation of growth factor signaling, plakophilin 1 switches from a desmosome-associated growth-inhibiting to a cytoplasmic proliferation-promoting function.

  6. In breast cancer, compared with normal tissue, PKP1 and PKP2 expressions were indifferent (P > 0.05), but PKP3 (show PKP3 Proteins) expression was significantly increased

  7. PKP1 loss secondary to promoter methylation, as well as other mechanisms, may promote the progression of Barrett's esophagus to esophageal adenocarcinoma in a subset of patients via decreased desmosome assembly and increased cell motility

  8. both loss of PKP1 and up-regulation of PKP3 (show PKP3 Proteins) expression are biologically important events in prostate cancer and are associated with a more aggressive phenotype

  9. These findings identify PKP1 as a regulator of translation and proliferation via modulation of eIF4A1 (show EIF4A1 Proteins) activity.

  10. the clinicopathologic features attest to the significant role of PKP1 in stabilization of desmosome structure and function, predominantly in the spinous layers of the epidermis

Plakophilin 1 (PKP1) Protein Profile

Protein Summary

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Plakophilin 1 Proteins (PKP1)

  • plakophilin 1 (PKP1)
  • plakophilin 1 (pkp1)
  • plakophilin 1 (Pkp1)
  • plakophilin 1 (LOC100338080)
  • plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) (PKP1)
  • plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) (Pkp1)
  • AI528551 protein
  • B6P protein
  • fb30d08 protein
  • PKP1 protein
  • wu:fb30d08 protein

Protein level used designations for Plakophilin 1 Proteins (PKP1)

plakophilin 1 , plakophilin-1 , band 6 protein , B6P , armadillo , band 6 , band-6 protein

GENE ID SPECIES
708177 Macaca mulatta
797838 Danio rerio
18772 Mus musculus
304822 Rattus norvegicus
100338080 Oryctolagus cuniculus
421158 Gallus gallus
5317 Homo sapiens
281405 Bos taurus
100733998 Cavia porcellus
101109291 Ovis aries
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