anti-Platelet Factor 4 (PF4) Antibodies

PF4 encodes a member of the CXC chemokine family. Additionally we are shipping Platelet Factor 4 Kits (91) and Platelet Factor 4 Proteins (74) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PF4 5196 P02776
PF4 56744 Q9Z126
PF4 360918 P06765
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Top anti-Platelet Factor 4 Antibodies at antibodies-online.com

Showing 10 out of 135 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, WB Detection of Human CXCL4/PF4 by Western Blot. Western blot shows lysates of human spleen tissue and human platelets. PVDF membrane was probed with 0.5 ug/mL of Mouse Anti-Human CXCL4/PF4 Monoclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$267.75
Details
Human Mouse Biotin EIA, WB   0.1 mg Log in to see 6 to 8 Days
$434.50
Details
Human Mouse Un-conjugated EIA, WB   0.2 mg Log in to see 6 to 8 Days
$555.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-PF4 antibody, Western blotting Lane 1: Recombinant Human CXCL4 Protein 10ng Lane 2: Recombinant Human CXCL4 Protein 5ng Lane 3: Recombinant Human CXCL4 Protein 2.5ng Anti-PF4 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Sheep Un-conjugated ELISA, IHC (p) Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP1-50290] - Analysis of anti-PF4 antibody with human placenta at concentration 5 ug/ml. 0.05 mg Log in to see 10 to 13 Days
$447.56
Details
Mouse Rabbit Un-conjugated ELISA, IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Fluorescein FACS Detection of CXCL4/PF4 in Human Immature Dendritic Cells by Flow Cytometry. Human immature dendritic cells were stained with Mouse Anti-Human CXCL4/PF4 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$267.75
Details
Human Mouse PE FACS Detection of CXCL4/PF4 in Human Dendritic Cells by Flow Cytometry. Human immature dendritic cells were stained with Mouse Anti-Human CXCL4/PF4 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$320.25
Details
Human Mouse Un-conjugated WB Detection limit for recombinant GST tagged PF4 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

PF4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Platelet Factor 4 Antibodies

  1. Human Monoclonal PF4 Primary Antibody for EIA, WB - ABIN954175 : Suvarna, Rauova, McCracken, Goss, Sachais, McKenzie, Reilly, Gunn, Cines, Poncz, Arepally: PF4/heparin complexes are T cell-dependent antigens. in Blood 2005 (PubMed)
    Show all 6 references for 954175

  2. Human Monoclonal PF4 Primary Antibody for EIA, WB - ABIN954174 : Arepally, Kamei, Park, Kamei, Li, Liu, Siegel, Kisiel, Cines, Poncz: Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies. in Blood 2000 (PubMed)
    Show all 6 references for 954174

  3. Human Monoclonal PF4 Primary Antibody for FACS, WB - ABIN4900200 : Dubrac, Quemener, Lacazette, Lopez, Zanibellato, Wu, Bikfalvi, Prats: Functional divergence between 2 chemokines is conferred by single amino acid change. in Blood 2010 (PubMed)

  4. Human Polyclonal PF4 Primary Antibody for ELISA, IHC (p) - ABIN4265396 : Zhang, Mercado-Uribe, Liu: Tumor stroma and differentiated cancer cells can be originated directly from polyploid giant cancer cells induced by paclitaxel. in International journal of cancer 2013 (PubMed)

More Antibodies against Platelet Factor 4 Interaction Partners

Human Platelet Factor 4 (PF4) interaction partners

  1. Endometrial CXCL4 mRNA concentrations were significantly increased during menstruation. In women with heavy menstrual bleeding, CXCL4 was reduced in endothelial cells during the menstrual phase compared with women with normal menstrual bleeding. These data implicate CXCL4 in endometrial repair after menses.

  2. Two haplotype blocks, one upstream to the coding region of UGT2A1 (rs146712414, P = 9.1 x 10(-5); odds ratio [OR], 1.34; 95% confidence interval [CI], 1.16-1.56) and one downstream of the genes PF4/PPBP/CXCL5 (rs1595009, P = 1.3 x 10(-4); OR, 1.32; 95% CI, 1.15-1.52), were associated with AgP.

  3. These data demonstrate that the CXCR2 (show CXCR2 Antibodies) network and CXCL4 play a role in the maintenance of normal HSC (show FUT1 Antibodies)/HPC cell fates, including survival and self-renewal.

  4. The major aim of this review article was to evaluate the role of CXCL4 in hematological malignancies, promotion of HSC (show FUT1 Antibodies) quiescence as well as BM niche cells.

  5. binding of PF4 to perlecan (show HSPG2 Antibodies) was found to inhibit both FGF2 (show FGF2 Antibodies) signaling and platelet activation

  6. CXCL4 plays an important role in pancreatic inflammation

  7. Data suggest that serum haptoglobin, fetuin-A, platelet factor-4, hs-CRP (high sensitive-C-reactive protein), SAP (serum amyloid P), AGP (alpha1-acid glycoprotein) levels of adolescents with metabolic syndrome are significantly higher than those of controls subjects.

  8. The hitherto unknown association of increased serum CXCL4 with features of microvascular impairment in primary Sjogren's syndrome, along with the negative association with features of lymphocytic response suggest clarifying the possible implication of this chemokine (show CCL1 Antibodies) in primary Sjogren's syndrome pathogenesis in larger studies.

  9. serum concentration of CXCL4 was significantly increased in patients with Chronic Liver Allograft Dysfunction (CLAD); CXCL4 mRNA was significantly increased in subjects with CLAD versus individuals without CLAD

  10. Plasma levels of CXCL4 are associated with tumour vascularity.

Mouse (Murine) Platelet Factor 4 (PF4) interaction partners

  1. These data demonstrate that the CXCR2 (show CXCR2 Antibodies) network and CXCL4 play a role in the maintenance of normal HSC (show FUT1 Antibodies)/HPC cell fates, including survival and self-renewal.

  2. Platelet-derived CXCL7 (show PPBP Antibodies) and CXCL4 contribute to the pathogenesis of acute lung injury.

  3. CXCL4 plays an important role in pancreatic inflammation

  4. Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage

  5. PF4 has a complex intramedullary life cycle with important implications in megakaryopoiesis and hematopoietic stem cell replication not seen with other tested alpha granule proteins.

  6. Heparin enhances antigen uptake and activation of the initial steps in the cellular immune response to PF4-containing complexes.

  7. Data indicate that platelet factor 4 (PF4) is involved directly in liver innate immune response against ischaemia-reperfusion injury (IRI) by regulating Th17 cell differentiation.

  8. CXCL4 regulates hematopoietic stem cell cell cycle activity.

  9. Platelet factor 4 has a role in regulating Th17 differentiation and cardiac allograft rejection

  10. Histones regulate activated protein C (show PROC Antibodies) formation in a manner similar to PF4 and suggest heparinoids may be benificial in sepsis.

Platelet Factor 4 (PF4) Antigen Profile

Protein Summary

This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function.

Gene names and symbols associated with anti-Platelet Factor 4 (PF4) Antibodies

  • platelet factor 4 (PF4) antibody
  • platelet factor 4 (Pf4) antibody
  • Cxcl4 antibody
  • PF-4 antibody
  • Pf4a antibody
  • RATPF4A antibody
  • Scyb4 antibody

Protein level used designations for anti-Platelet Factor 4 (PF4) Antibodies

platelet factor 4 (chemokine (C-X-C motif) ligand 4) , C-X-C motif chemokine 4 , chemokine (C-X-C motif) ligand 4 , iroplact , oncostatin-A , PF-4

GENE ID SPECIES
703451 Macaca mulatta
740477 Pan troglodytes
5196 Homo sapiens
56744 Mus musculus
360918 Rattus norvegicus
507790 Bos taurus
101104401 Ovis aries
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