Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
PF4 encodes a member of the CXC chemokine family. Additionally we are shipping Platelet Factor 4 Kits (90) and Platelet Factor 4 Proteins (76) and many more products for this protein.
Showing 10 out of 122 products:
Human Monoclonal PF4 Primary Antibody for EIA, WB - ABIN954175
Suvarna, Rauova, McCracken, Goss, Sachais, McKenzie, Reilly, Gunn, Cines, Poncz, Arepally: PF4/heparin complexes are T cell-dependent antigens. in Blood 2005
Show all 6 references for ABIN954175
Human Monoclonal PF4 Primary Antibody for EIA, WB - ABIN954174
Arepally, Kamei, Park, Kamei, Li, Liu, Siegel, Kisiel, Cines, Poncz: Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies. in Blood 2000
Show all 6 references for ABIN954174
Human Polyclonal PF4 Primary Antibody for ELISA, IHC (p) - ABIN4265396
Zhang, Mercado-Uribe, Liu: Tumor stroma and differentiated cancer cells can be originated directly from polyploid giant cancer cells induced by paclitaxel. in International journal of cancer 2013
Human Monoclonal PF4 Primary Antibody for FACS, WB - ABIN4900200
Dubrac, Quemener, Lacazette, Lopez, Zanibellato, Wu, Bikfalvi, Prats: Functional divergence between 2 chemokines is conferred by single amino acid change. in Blood 2010
The hitherto unknown association of increased serum CXCL4 with features of microvascular impairment in primary Sjogren's syndrome, along with the negative association with features of lymphocytic response suggest clarifying the possible implication of this chemokine (show CCL1 Antibodies) in primary Sjogren's syndrome pathogenesis in larger studies.
serum concentration of CXCL4 was significantly increased in patients with Chronic Liver Allograft Dysfunction (CLAD); CXCL4 mRNA was significantly increased in subjects with CLAD versus individuals without CLAD
Plasma levels of CXCL4 are associated with tumour vascularity.
Data suggest that, in patients with hypothyroid autoimmune thyroiditis, PF4/CXCL4 serum levels are significantly lower in those with subclinical hypothyroidism than in euthyroid control subjects.
Expression of CXCL4 and aquaporin 3 (show AQP3 Antibodies) and 10 mRNAs in middle ear effusion is associated with the pathophysiology of otitis media with effusion.
PF4 changed its structure upon binding to polyP in a similar way as seen in PF4/heparin complexes. PF4/polyP complexes exposed neoepitopes to which human anti-PF4/heparin antibodies bound.
PF4 has a complex intramedullary life cycle with important implications in megakaryopoiesis and hematopoietic stem cell replication not seen with other tested alpha granule proteins.
A subset of heparin-treated patients produce subthreshold levels of platelet-activating anti-PF4/heparin antibodies that do not cause heparin-induced thrombocytopenia.
Synovial Cxcl4 mRNA and protein were increased in early rheumatoid arthritis compared to uninflamed controls and resolving arthritis.
Results found that CXCL4 plasma levels did not differ between patients with and without coronary artery disease. Also, no association between CXCL4 levels and plaque characteristics including plaque volume, calcium score, or vascular remodeling.
Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage
Heparin enhances antigen uptake and activation of the initial steps in the cellular immune response to PF4-containing complexes.
Data indicate that platelet factor 4 (PF4) is involved directly in liver innate immune response against ischaemia-reperfusion injury (IRI) by regulating Th17 cell differentiation.
CXCL4 regulates hematopoietic stem cell cell cycle activity.
Platelet factor 4 has a role in regulating Th17 differentiation and cardiac allograft rejection
Histones regulate activated protein C (show PROC Antibodies) formation in a manner similar to PF4 and suggest heparinoids may be benificial in sepsis.
PF4 drives a vascular smooth muscle inflammatory phenotype including a decline in differentiation markers, increased cytokine production, and cell proliferation.
Peptide inhibition of CXCL4-CCL5 (show CCL5 Antibodies) interactions may represent a viable translational strategy to limit progression of abdominal aortic aneurysms.
PF4 expression on intestinal epithelial cells is increased after IR at both the mRNA and protein levels. In conclusion, these findings demonstrate that may PF4 represent an important mediator of local and remote tissue damage.
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function.
platelet factor 4 (chemokine (C-X-C motif) ligand 4)
, C-X-C motif chemokine 4
, chemokine (C-X-C motif) ligand 4