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PAFAH1B3 encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. Additionally we are shipping Platelet-Activating Factor Acetylhydrolase 1b, Catalytic Subunit 3 (29kDa) Kits (20) and Platelet-Activating Factor Acetylhydrolase 1b, Catalytic Subunit 3 (29kDa) Proteins (14) and many more products for this protein.
Showing 10 out of 71 products:
Human Monoclonal PAFAH1B3 Primary Antibody for IF, ELISA - ABIN562094
Page, Münch, Horn, Kuhn, Colombo, Reiner, Boutros, Steiner, Lichtenthaler, Haass: Loss of PAFAH1B2 reduces amyloid-? generation by promoting the degradation of amyloid precursor protein C-terminal fragments. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
PAFAH1B2 (show PAFAH1B2 Antibodies) and 1B3 are important in maintaining cancer pathogenicity across a wide spectrum of cancer types.
PAFAH1B3 as a critical metabolic node in breast cancer
PAFAH1B3 has been found to be differentially methylated in head and neck squamous cell carcinoma.
intracellular type I PAF acetylhydrolase (show ASPG Antibodies) (PAFAH1B2 (show PAFAH1B2 Antibodies) and PAFAH1B3) is the major aspirin hydrolase of human blood
These results indicate an antagonistic effect of alpha1, alpha2 and Ndel1 for Lis1 binding, probably to modulate dynein functions in vivo.
Catalytic subunits of the Pafah1b complex, Pafah1b2 (show PAFAH1B2 Antibodies) and Pafah1b3, specifically bind to the NPxYL sequence of VLDLR (show VLDLR Antibodies), but not to ApoER2 (show LRP8 Antibodies).
study examined biochemical interactions of Pafah1b Alpha1 & Alpha2 subunits with the Reelin (show RELN Antibodies) signaling machinery & demonstrated that Alpha2, but not Alpha1, binds Dab1 (show DAB1 Antibodies) in a phosphorylation-independent manner
These observations support the further development of PMS-601 as an adjunctive therapy for HIV-1 associated neurocognitive disorders.
This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.
platelet-activating factor acetylhydrolase, isoform Ib, subunit 3 (29kDa)
, platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa
, PAF acetylhydrolase 29 kDa subunit
, PAF-AH 29 kDa subunit
, PAF-AH subunit gamma
, PAFAH subunit gamma
, platelet-activating factor acetylhydrolase IB subunit gamma
, PAF-AH alpha 1
, platelet-activating factor acetylhydrolase alpha 1 subunit
, platelet-activating factor acetylhydrolase, isoform 1b, alpha1 subunit
, platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
, platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit
, PAF-AH1b alpha 1 subunit
, platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit (29kD)
, PAF-AH gamma