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Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Additionally we are shipping PAIP2 Proteins (10) and many more products for this protein.
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Human Polyclonal PAIP2 Primary Antibody for EIA, WB - ABIN953979
Onesto, Berra, Grépin, Pagès: Poly(A)-binding protein-interacting protein 2, a strong regulator of vascular endothelial growth factor mRNA. in The Journal of biological chemistry 2004
Show all 3 references for 953979
Human Monoclonal PAIP2 Primary Antibody for EIA, WB - ABIN1449405
Khaleghpour, Svitkin, Craig, DeMaria, Deo, Burley, Sonenberg: Translational repression by a novel partner of human poly(A) binding protein, Paip2. in Molecular cell 2001
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Paip2 is a host antiviral restriction factor antagonized by PABP accumulation in HCMV-infected cells
Role of PAIP2 in modulation of GLUT5 (show SLC2A5 Antibodies) mRNA stability.
PAIP2 is a crucial regulator of VEGF mRNA and has a role in regulating angiogenesis
The turnover of Paip2 in the cell is mediated by EDD and is regulated by PABP.
this study demonstrated that activity-dependent degradation of PAIP2A relieves translational inhibition of memory-related genes through PABP (show EBP Antibodies) reactivation and conclude that PAIP2A is a pivotal translational regulator of synaptic plasticity and memory.
PABP (show EBP Antibodies) interacting protein 2A (PAIP2A) regulates specific key proteins during spermiogenesis in the mouse.
Paip2 is able to function as a tumor suppressor
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
poly(A) binding protein interacting protein 2
, polyadenylate-binding protein-interacting protein 2
, PABP-interacting protein 2
, poly(A)-binding protein-interacting protein 2
, PABC1-interacting protein 2
, polyA-binding protein-interacting protein 2
, polyadenylate-binding protein interacting protein 2
, spoly(A) binding protein interacting protein 2
, Pabp-interacting protein 2