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Polyhomeotic Homolog 3 (Drosophila) Proteins (PHC3)

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Additionally we are shipping Polyhomeotic Homolog 3 (Drosophila) Antibodies (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat PHC3 PHC3 310258  
PHC3 80012 Q8NDX5
PHC3 241915 Q8CHP6
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Top Polyhomeotic Homolog 3 (Drosophila) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PHC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Polyhomeotic Homolog 3 (Drosophila) (PHC3) Interaction Partners

Human Polyhomeotic Homolog 3 (Drosophila) (PHC3) interaction partners

  1. Data show that polycomb (show CBX2 Proteins)-group proteins BMI1 (show BMI1 Proteins), PHC3, CBX6 (show CBX6 Proteins) and CBX7 (show CBX7 Proteins) expression was significantly increased during imatinib treatment.

  2. PHC3 amplification may emerge as a biomarker in cancer.

  3. SAM (show TTN Proteins) linker controls PHC3 SAM (show TTN Proteins) polymerization

  4. PHC3 is a tumor suppressor in osteosarcoma cells abd its suppression may be caused by modification of polycomb (show CBX2 Proteins) repressive complex 1 in cancer cells.

  5. loss of PHC3 may favor tumorigenesis by potentially disrupting the ability of cells to remain in G(0)

Polyhomeotic Homolog 3 (Drosophila) (PHC3) Protein Profile

Protein Summary

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).

Gene names and symbols associated with PHC3

  • polyhomeotic homolog 3 (Drosophila) (Phc3)
  • polyhomeotic homolog 3 (Drosophila) (PHC3)
  • polyhomeotic like 3 (LOC100346297)
  • polyhomeotic-like 3 (Drosophila) (Phc3)
  • E030046K01Rik protein
  • Edr3 protein
  • Hph3 protein

Protein level used designations for PHC3

polyhomeotic-like protein 3 , polyhomeotic like 3 , polyhomeotic homolog 3 (Drosophila) , early development regulator 3 , early development regulatory protein 3 , homolog of polyhomeotic 3 , polyhomeotic 3

GENE ID SPECIES
310258 Rattus norvegicus
460843 Pan troglodytes
100346297 Oryctolagus cuniculus
80012 Homo sapiens
241915 Mus musculus
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