anti-Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) Antibodies

POLR3B encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. Additionally we are shipping Polymerase (RNA) III (DNA Directed) Polypeptide B Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POLR3B 362858  
POLR3B 55703 Q9NW08
POLR3B 70428 P59470
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Top anti-Polymerase (RNA) III (DNA Directed) Polypeptide B Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged POLR3B is 0.1 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Mouse Rabbit Un-conjugated WB POLR3B Antibody (N-term) (ABIN657740) western blot analysis in mouse spleen tissue lysates (35 µg/lane). This demonstrates the POLR3B antibody detected the POLR3B protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
$478.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Fruit Fly Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of POLR3B staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wit Western blot analysis of POLR3B expression in Hela (A), HepG2 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB Western Blot: POLR3B Antibody [NBP1-54363] - Human Heart lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details

POLR3B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human ,
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,
Mouse (Murine)


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Top referenced anti-Polymerase (RNA) III (DNA Directed) Polypeptide B Antibodies

  1. Human Monoclonal POLR3B Primary Antibody for ELISA, WB - ABIN527631 : Shen, Lei, Liu, Zheng, Song, Marc, Wang, Sun, Liang: Identification and characterization of INMAP, a novel interphase nucleus and mitotic apparatus protein that is involved in spindle formation and cell cycle progression. in Experimental cell research 2009 (PubMed)

  2. Cow (Bovine) Polyclonal POLR3B Primary Antibody for WB - ABIN2783516 : Yee, Gong, Huang, Lorent, Dolan, Maraia, Pack: Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development. in PLoS biology 2007 (PubMed)

More Antibodies against Polymerase (RNA) III (DNA Directed) Polypeptide B Interaction Partners

Human Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) interaction partners

  1. The spectrum of phenotypes resulting from POLR3B mutations is wider than previously believed.

  2. Findings suggest that AP-1 factors are regulators of RNA polymerase III (Pol III)-driven 5S rRNA and U6 snRNA expression with a potential role in cell proliferation.

  3. Multicenter retrospective study to collect neuroradiologic, clinical, and molecular data of patients with mutations in POLR3A (show POLR3A Antibodies) and POLR3B without the classic MRI (show C7ORF49 Antibodies) phenotype: diffuse hypomyelination is not an obligatory feature of POLR3-related disorders; two distinct patterns, selective involvement of the corticospinal tracts and cerebellar atrophy, are added to the MRI (show C7ORF49 Antibodies) presentation of POLR3-related disorders

  4. first reports of long deletions causing POLR3-related leukodystrophy, suggesting that deletions and duplications in POLR3A (show POLR3A Antibodies) or POLR3B should be investigated in patients with a compatible phenotype

  5. Mutations in POLR3A (show POLR3A Antibodies) or POLR3B are rare in patients with unclassified hypomyelination.

  6. INMAP as a model regulator of CENP-B (show CENPB Antibodies)

  7. These results suggest that INMAP might function through p53 (show TP53 Antibodies)/p21 (show CDKN1A Antibodies) pathways.

  8. Most patients with 4H leukodystrophy carried the common c.1568T>A POLR3B mutation on one allele.

  9. MRI (show C7ORF49 Antibodies) in patients with POLR3B mutations revealed smaller cerebellar structures, especially vermis, than those in POLR3A (show POLR3A Antibodies) mutations. MRI (show C7ORF49 Antibodies) also showed milder hypomyelination in patients with POLR3B mutations than those with POLR3A (show POLR3A Antibodies) mutations

  10. Investigated POLR3A (show POLR3A Antibodies) and POLR3B mutations in patients with genetically unexplained hypomyelinating leukodystrophies with features of Pol III-related leukodystrophies. Recessive mutations in POLR3A (show POLR3A Antibodies) or POLR3B were uncovered in all 14 patients.

Mouse (Murine) Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) interaction partners

  1. The Polr3b in the hippocampus in the prefrontal cortex of the DBA (show RPS19 Antibodies)/2 J strain were up-regulated.

Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) Antigen Profile

Protein Summary

This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with POLR3B

  • polymerase (RNA) III (DNA directed) polypeptide B (Polr3b) antibody
  • polymerase (RNA) III (DNA directed) polypeptide B (POLR3B) antibody
  • 2700078H01Rik antibody
  • A330032P03Rik antibody
  • C128 antibody
  • C85372 antibody
  • HLD8 antibody
  • RGD1565311 antibody
  • RPC2 antibody

Protein level used designations for POLR3B

DNA-directed RNA polymerase III subunit RPC2 , DNA-directed RNA polymerase III 127.6 kDa polypeptide , DNA-directed RNA polymerase III subunit B , RNA polymerase III subunit C2 , C128 , DNA-directed RNA polymerase III B , RNA polymerase III subunit RPC2 homolog

GENE ID SPECIES
362858 Rattus norvegicus
418071 Gallus gallus
474531 Canis lupus familiaris
55703 Homo sapiens
70428 Mus musculus
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