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Pre-B-Cell Leukemia Homeobox Protein 1 Proteins (PBX1)

PBX1 encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Additionally we are shipping PBX1 Antibodies (67) and PBX1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PBX1 18514 P41778
PBX1 5087 P40424
Rat PBX1 PBX1 304947  
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Top PBX1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,942.50
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,942.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PBX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) Interaction Partners

Mouse (Murine) Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) interaction partners

  1. Thus, PTBP1 (show PTBP1 Proteins) controls the activity of Pbx1 to suppress its neuronal transcriptional program prior to induction of neuronal progenitor cells development.

  2. this study showed that the lupus susceptibility gene Pbx1 not only contributes to autoimmune pathology by impairing T cell tolerance, but also impairs the function of mesenchymal stem cells, which may also contribute to the disease directly or indirectly.

  3. Pbx1-dependent control of VMC (show PLXNA3 Proteins) differentiation kinetics underlies gross renal vascular patterning.

  4. Results thus show how Pbx1 controls Fgf10 (show FGF10 Proteins) in the developing lung.

  5. Prep1 and Meis1 (show MEIS1 Proteins) competition for Pbx1 binding regulates protein stability and tumorigenesis.

  6. These results demonstrate a role for Pbx1 in restraining myeloid maturation while maintaining lymphoid potential to appropriately regulate progenitor reservoirs.

  7. The Systemic Lupus Erythematosus-associated Pbx1-d isoform acts as a dominant-negative transcriptional regulator.

  8. Data have demonstrated the presence of Meis, Pbx, and Prep proteins during early lineage segregation in mammals: Meis1, Meis3, Pbx1, Pbx2, Pbx3, and Prep1 in the mouse.

  9. In Pbx1-deficient dopaminergic neurons, the high affinity netrin-1 (show NTN1 Proteins) receptor, deleted in colon cancer, is down-regulated.

  10. Data suggest that PBX1 regulates adipocyte development at multiple levels, promoting the generation of NC-derived APs (show SH2B2 Proteins) during embryogenesis, while favoring APs (show SH2B2 Proteins) proliferation and preventing their commitment to the adipocyte lineage in postnatal life.

Human Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) interaction partners

  1. Data identifies PBX1 amplification as a functional hallmark of aggressive ERalpha (show ESR1 Proteins)-positive breast cancers.

  2. We observed significant enrichment of the neuroactive ligand-receptor interaction pathway in TCF3 (show TCF3 Proteins)-PBX1 as well as an enrichment of genes involved in immunity and infection pathways in ETV6 (show ETV6 Proteins)-RUNX1 (show RUNX1 Proteins) subtype

  3. This association study successfully identified two susceptibility Single Nucleotide Polymorphisms, (WNT9B (show WNT9B Proteins) and PBX1) associated with Mayer-Rokitansky-Kuster-Hauser syndrome risk, both separately and interactively.

  4. PBX1 promotes frontal cortex patterning by repressing genes that promote dorsocaudal fate.

  5. When intensive chemotherapy was used, the TCF3 (show TCF3 Proteins)-PBX1 was associated with a favorable outcome in childhood pre-B ALL.

  6. Induction of PBX1 expression was associated with 13-cisRA responsiveness in neuroblastoma (show ARHGEF16 Proteins).

  7. In this study, we showed that TCF3 (show TCF3 Proteins)-PBX1 positive pediatric BCP (show OPN1SW Proteins)-ALL patients treated according to the JACLS ALL02 and CCLSG ALL2004 protocol had favorable outcomes

  8. E2A (show TCF3 Proteins)-PBX1 fusion gene caused by t(1;19)(q23;p13) may be a common genetic change in AIS (show AR Proteins) and a survival determinant for female AIS (show AR Proteins) patients at early stage.

  9. Data indicate that among 31 thymus development-related genes, PBX1 copy number gain and FOXC1 (show FOXC1 Proteins) copy number loss were presented in 43.0% and 39.5% of the tumors, respectively.

  10. E2a (show TCF3 Proteins)-pbx1-positive patients are associated with more aggressive acute lymphoblastic leukemia.

Xenopus laevis Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) interaction partners

  1. These overall data suggest that ZFPIP and Pbx1 could be partners and cooperate in the regulation of essential neural genes during Xenopus development.

PBX1 Protein Profile

Protein Summary

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1\;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PBX1

  • pre B cell leukemia homeobox 1 (Pbx1)
  • pre-B-cell leukemia homeobox 1 (PBX1)
  • pre-B-cell leukemia homeobox 1 (Pbx1)
  • pre-B-cell leukemia homeobox 1 (pbx1)
  • 2310056B04Rik protein
  • AI848790 protein
  • AU015730 protein
  • D230003C07Rik protein
  • Pbx-1 protein
  • PBX1A protein
  • pbx1b protein
  • Xpbx1 protein
  • Xpbx1b protein

Protein level used designations for PBX1

homeobox protein PBX1 , pre B-cell leukemia transcription factor 1 , pre-B-cell leukemia transcription factor 1 , homeobox protein PRL , Homeobox protein pbx1 , pre-B-cell leukemia transcription factor 1b

GENE ID SPECIES
18514 Mus musculus
395505 Gallus gallus
5087 Homo sapiens
488669 Canis lupus familiaris
304947 Rattus norvegicus
399184 Xenopus laevis
540688 Bos taurus
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