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Progesterone Receptor Membrane Component 1 Proteins (PGRMC1)

PGRMC1 encodes a putative membrane-associated progesterone steroid receptor. Additionally we are shipping PGRMC1 Antibodies (37) and PGRMC1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PGRMC1 10857 O00264
PGRMC1 53328 O55022
PGRMC1 291948 P70580
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Top PGRMC1 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,326.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,333.83
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,333.83
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,337.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PGRMC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Progesterone Receptor Membrane Component 1 (PGRMC1) Interaction Partners

Zebrafish Progesterone Receptor Membrane Component 1 (PGRMC1) interaction partners

  1. These results indicate that maintenance of Pgrmc1 signaling is required for Egfr expression on zebrafish oocyte cell membranes and for conserving the functions of Egfr in maintaining meiotic arrest through estrogen activation of Gper.

Human Progesterone Receptor Membrane Component 1 (PGRMC1) interaction partners

  1. Haem-mediated PGRMC1 dimerization is required for interactions with EGFR (show EGFR Proteins) and cytochromes P450 (show CYP2B6 Proteins), cancer proliferation and chemoresistance against anti-cancer drugs.

  2. indicate that PGRMC1 regulates hepcidin (show HAMP Proteins) gene expression through an evolutionarily conserved mechanism

  3. results suggested that PGRMC1 and sigma2 receptors are two different molecular entities.

  4. PGRMC1 is the major progesterone receptor (show PGR Proteins) eliciting the protective effects of Norgestrel, a synthetic female progesterone hormone.

  5. coding mutations of PGRMC1 do not seem to be a common cause of the disease in Han Chinese

  6. PGRMC1 overexpression led to the epithelial-mesenchymal transition and chemoresistance in uterine sarcoma.

  7. Loss of PGRMC1 expression is associated with endometrial tumor cell viability during chemotherapeutic stress.

  8. PGRMC1 binds to key components of the autophagy machinery and is required for the degradative activity of autophagy

  9. PGRMC1 expression appears to be diminished in pregnant women with preterm premature rupture of the membranes.

  10. PGRMC-1 expression is downregulated in the endometria from women with advanced stage endometriosis.

Cow (Bovine) Progesterone Receptor Membrane Component 1 (PGRMC1) interaction partners

  1. PGRMC1 protein expression and cellular distribution in cumulus cells

  2. data indicate variable expression of progesterone receptor membrane component 1 and 2 and serpine mRNA binding protein 1 mRNA and protein in bovine corpus luteum and suggest that progesterone may regulate corpus luteum function via its membrane receptors

  3. Alterations in PGRMC1 and/or AURKB (show AURKB Proteins) localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.

  4. Data suggest that expression of PGRMC1 in bovine oviduct is primarily in luminal epithelium and is primarily cytoplasmic. Expression of PR (progesterone receptor (show PGR Proteins)), PGRMC1, and PGRMC2 (show PGRMC2 Proteins) are not affected by pregnancy or presence of corpus luteum.

  5. analysis of expression of progesterone receptor membrane component 1, serpine mRNA binding protein 1 and nuclear progesterone receptor (show PGR Proteins) isoforms A and B in the bovine myometrium during the estrous cycle and early pregnancy

  6. With the exception of the corpora lutea, PGRMC1 localization showed similar pattern during different stages of the estrous cycle.

  7. PGRMC1 is expressed in bovine oocytes and its localization changes at specific stages of oocyte maturation, which may be specifically related to the mechanism by which chromosomes segregate.

  8. PGRMC1 mRNA is expressed in bovine CL and this expression varies throughout the luteal phase. It is assumed that PGRMC1 may be involved in a non-genomic effect of P(4) on luteal cells.

Mouse (Murine) Progesterone Receptor Membrane Component 1 (PGRMC1) interaction partners

  1. PGRMC1 expressed on the cell surface of beta cells was shown to interact with the activated GLP-1R (show GLP1R Proteins) to enhance the insulinotropic actions of GLP-1 (show GCG Proteins).

  2. The aim of this study was to assess the expression, localization and hormonal regulation of two novel P(4) receptor candidates, P(4) receptor membrane component (PGRMC) 1 and PGRMC2 (show PGRMC2 Proteins), as well as the PGRMC1 partner Serpine 1 (show SERPINE1 Proteins) mRNA binding protein (SERBP1 (show SERBP1 Proteins)).

PGRMC1 Protein Profile

Protein Summary

This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney.

Gene names and symbols associated with PGRMC1

  • progesterone receptor membrane component 1 (pgrmc1)
  • progesterone receptor membrane component 1 (PGRMC1)
  • progesterone receptor membrane component 1 (Pgrmc1)
  • 25-Dx protein
  • 25Dx protein
  • AA415812 protein
  • DKFZp469D0815 protein
  • HPR6.6 protein
  • MGC89150 protein
  • MPR protein
  • PPMR protein
  • VEMA protein
  • wu:fa94d03 protein
  • zgc:103577 protein

Protein level used designations for PGRMC1

progesterone receptor membrane component 1 , fa94d03 , membrane-associated progesterone receptor component 1 , progesterone binding protein , steroid membrane binding protein , acidic 25 kDa protein , membrane-bound progesterone receptor , ventral midline antigen

GENE ID SPECIES
448590 Xenopus (Silurana) tropicalis
492520 Danio rerio
736142 Pan troglodytes
100174262 Pongo abelii
10857 Homo sapiens
481029 Canis lupus familiaris
396946 Sus scrofa
317706 Bos taurus
53328 Mus musculus
291948 Rattus norvegicus
772196 Gallus gallus
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