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Programmed Cell Death 5 Proteins (PDCD5)

PDCD5 encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. Additionally we are shipping PDCD5 Antibodies (64) and PDCD5 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDCD5 9141 O14737
PDCD5 56330 P56812
Rat PDCD5 PDCD5 292814  
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Top PDCD5 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,249.50
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$352.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 5 to 9 Days
$574.35
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   2 μg Log in to see 7 to 8 Days
$117.48
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   1 mg Log in to see 6 Days
$99.63
Details

PDCD5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced PDCD5 Proteins

  1. Human PDCD5 Protein expressed in Escherichia coli (E. coli) - ABIN667714 : Chen, Sun, Han, Zhang, Song, Di, Ma: Nuclear translocation of PDCD5 (TFAR19): an early signal for apoptosis? in FEBS letters 2001 (PubMed)
    Show all 3 references for ABIN667714

More Proteins for Programmed Cell Death 5 (PDCD5) Interaction Partners

Human Programmed Cell Death 5 (PDCD5) interaction partners

  1. Endogenous PDCD5 overexpression accelerated multiple myeloma cell apoptosis under dexamethasone treatment.

  2. Studies indicate that programmed cell death 5 (PDCD5) interacts with the tumor protein p53 (p53 (show TP53 Proteins)) pathway to promote cell apoptosis.

  3. This review describes what is known about PDCD5 and its cellular functions. [review]

  4. The results suggest a role of PDCD5 in the regulation of p53 (show TP53 Proteins) function but unrelated to cell cycle arrest or apoptosis, at least in the cell types investigated.

  5. PDCD5 selectively mediates HDAC3 (show HDAC3 Proteins) dissociation from p53 (show TP53 Proteins), which induces HDAC3 (show HDAC3 Proteins) cleavage and ubiquitin-dependent proteasomal degradation. This is a a mechanism for p53 (show TP53 Proteins) activation via PDCD5-dependent HDAC3 (show HDAC3 Proteins) decay under genotoxic stress conditions.

  6. PDCD5 expression is negatively correlated with disease progression and stage in ovarian cancer.

  7. These findings uncovered an apoptotic signaling cascade linking YAF2 (show YAF2 Proteins), PDCD5, and TP53 (show TP53 Proteins) during genotoxic stress responses.

  8. Transgenic mice with systemic overexpression of human PDCD5 were protected from cardiac remodeling.

  9. Findings have uncovered an apoptotic signaling cascade linking PDCD5, OTUD5 (show OTUD5 Proteins), and p53 (show TP53 Proteins) during genotoxic stress responses.

  10. Authors identified DNAJB1 (show DNAJB1 Proteins) as a negative regulator of PDCD5-mediated apoptosis and found that the apoptosis network of PDCD5 regulates cancer cell death.

Mouse (Murine) Programmed Cell Death 5 (PDCD5) interaction partners

  1. PDCD5 selectively mediates HDAC3 (show HDAC3 Proteins) dissociation from p53 (show TP53 Proteins), which induces HDAC3 (show HDAC3 Proteins) cleavage and ubiquitin-dependent proteasomal degradation. This is a a mechanism for p53 (show TP53 Proteins) activation via PDCD5-dependent HDAC3 (show HDAC3 Proteins) decay under genotoxic stress conditions.

  2. These findings uncovered an apoptotic signaling cascade linking YAF2 (show YAF2 Proteins), PDCD5, and TP53 (show TP53 Proteins) during genotoxic stress responses.

  3. Transgenic mice with systemic overexpression of human PDCD5 were protected from cardiac remodeling.

  4. It is implied that overexpression of PDCD5 causes the increase in caspase-3 (show CASP3 Proteins) activity and the subsequent increase of apoptosis in cochlear hair cells and SGNs, and thereby plays a role in the pathogenesis of presbycusis.

  5. PDCD5 activity in T cells suppresses autoimmunity by modulating regulatory T-cells.

  6. The expression levels of PDCD5 and caspase 3 (show CASP3 Proteins) in the cochlea of C57 mice increase with age.

  7. Suppresses the pathogenicity of transplanted mouse erythroleukemia (MEL (show RAB8A Proteins)) cells in mice.

PDCD5 Protein Profile

Protein Summary

This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12

Gene names and symbols associated with PDCD5

  • programmed cell death 5 (pdcd5)
  • programmed cell death 5 (PDCD5)
  • hypothetical protein (pdcd5)
  • programmed cell death 5 (Pdcd5)
  • 2200003D22Rik protein
  • AA408513 protein
  • DKFZp468P187 protein
  • Tfar19 protein
  • zgc:56315 protein

Protein level used designations for PDCD5

programmed cell death protein 5 , programmed cell death 5 , hypothetical protein , TF-1 cell apoptosis-related protein 19 , TF1 cell apoptosis-related gene 19 , TFAR19 novel apoptosis-related , TF-1 cell apoptosis related gene-19 protein

GENE ID SPECIES
394152 Danio rerio
415765 Gallus gallus
455920 Pan troglodytes
476499 Canis lupus familiaris
495300 Xenopus laevis
549765 Xenopus (Silurana) tropicalis
702277 Macaca mulatta
1455494 Sulfolobus solfataricus P2
100167298 Acyrthosiphon pisum
100172347 Pongo abelii
100196200 Salmo salar
100528677 Ictalurus punctatus
9141 Homo sapiens
56330 Mus musculus
292814 Rattus norvegicus
509123 Bos taurus
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