PDCD5 Protein (His tag)

Catalog No. ABIN7318876

Product Details

Target: PDCD5 (Programmed Cell Death 5 (PDCD5))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PDCD5 protein is labelled with His tag.

Purpose: Recombinant Human PDCD5/TFAR19 Protein (His Tag)

Sequence: Met 1-Tyr125

Characteristics: Recombinant Human Programmed Cell Death Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Tyr125 is expressed with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: PDCD5 (Programmed Cell Death 5 (PDCD5))

Alternative Name: PDCD5/TFAR19 (PDCD5 Products)

Synonyms: zgc:56315 Protein, tfar19 Protein, DKFZp468P187 Protein, TFAR19 Protein, 2200003D22Rik Protein, AA408513 Protein, Tfar19 Protein, programmed cell death 5 Protein, programmed cell death 5 S homeolog Protein, DNA-binding protein Protein, pdcd5 Protein, PDCD5 Protein, pdcd5.S Protein, SSO_RS01750 Protein, Pdcd5 Protein

Background:

Background: Programmed Cell Death Protein 5 (PDCD5) is a member of the PDCD5 family. PDCD5 is expressed in tumor cells during apoptosis, independent of apoptosis-inducing stimuli. This protein may function in the process of apoptosis. PDCD5 is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 may play an important regulator of K (lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. PDCD5 is an important novel protein that regulates both apoptotic and non-apoptotic programmed cell death.

Synonym: Programmed Cell Death Protein 5, TF-1 Cell Apoptosis-Related Protein 19, Protein TFAR19, PDCD5, TFAR19

Molecular Weight: 16.4 kDa

UniProt: O14737