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Programmed Cell Death 6 Proteins (PDCD6)

PDCD6 encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Additionally we are shipping PDCD6 Antibodies (78) and PDCD6 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDCD6 10016 O75340
PDCD6 18570 P12815
Rat PDCD6 PDCD6 308061  
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Top PDCD6 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag Programmed Cell Death 6 (PDCD6) (AA 1-191), (full length) protein (GST tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   2 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   2 μg Log in to see 6 Days
$168.54
Details

PDCD6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced PDCD6 Proteins

  1. Human PDCD6 Protein expressed in Escherichia coli (E. coli) - ABIN667892 : Suzuki, Kawasaki, Inuzuka, Okumura, Kakiuchi, Shibata, Wakatsuki, Maki: Structural basis for Ca2+ -dependent formation of ALG-2/Alix peptide complex: Ca2+/EF3-driven arginine switch mechanism. in Structure (London, England : 1993) 2008 (PubMed)
    Show all 2 references for ABIN667892

  2. Human PDCD6 Protein expressed in Escherichia coli (E. coli) - ABIN1047560 : Kitaura, Matsumoto, Satoh, Hitomi, Maki: Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN1047560

More Proteins for Programmed Cell Death 6 (PDCD6) Interaction Partners

Human Programmed Cell Death 6 (PDCD6) interaction partners

  1. Our results suggest that PDCD6 may play an important role in the pathogenesis of cervical squamous cell carcinoma

  2. PDCD6 may represent a biomarker candidate gene that could help to identify a group of patients at high risk for recurrence and death.

  3. Palmitoylation sites and the N-terminal Pro-rich region were necessary for efficient secretion, but ABSs (ALG-2-binding sites) were dispensable.

  4. The present study provided evidence that rs4957014 and rs3756712 are associated with Uterine leiomyoma (UL) risk, the results indicated that genetic polymorphisms in PDCD6 may contribute to the development of UL.

  5. CHERP (show CHERP Proteins) and ALG-2 participate in regulation of alternative splicing of IP3R1 (show ITPR1 Proteins) pre-mRNA and provide new insights into post-transcriptional regulation of splicing variants in Ca(2 (show CA2 Proteins)+) signaling pathways.

  6. the binding of ALG-2 to IST1 (show IST1 Proteins) is Ca(2 (show CA2 Proteins)+)-dependent

  7. the current study indicates that PDCD6 gene may be a new susceptibility gene to endometriosis.

  8. The results of this study show that rs4957014G/T is associated with an increased risk of non-small cell lung cancer (NSCLC), which suggest that PDCD6 gene single nucleotide polymorphism is a risk factor for susceptibility of NSCLC.

  9. we conclude that a novel p53 (show TP53 Proteins)-responsive gene PDCD6 is accumulated in the nucleus and induces apoptosis in response to DNA damage.

  10. PDCD6 seems to play an important role in ovarian cancer progression.

Mouse (Murine) Programmed Cell Death 6 (PDCD6) interaction partners

  1. Substitution of either L52 with Ala or F148 with Ser (show SIGLEC1 Proteins) of ALG-2 caused loss of binding abilities to PLSCR3 (show PLSCR3 Proteins) lacking type 1 motif but retained those to PLSCR3 (show PLSCR3 Proteins) lacking type 2 motif

  2. ALG-2 is physiologically dispensable for apoptotic responses (ALG-2 protein)

PDCD6 Protein Profile

Protein Summary

This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Gene names and symbols associated with PDCD6

  • programmed cell death 6 (pdcd6)
  • programmed cell death 6 (PDCD6)
  • programmed cell death 6 (Pdcd6)
  • alg-2 protein
  • Alg2 protein
  • AV299538 protein
  • MA-3 protein
  • MGC52821 protein
  • MGC132114 protein
  • PDCD6 protein
  • PEF1B protein
  • PS2 protein
  • zgc:63952 protein

Protein level used designations for PDCD6

programmed cell death 6 , programmed cell death protein 6 , apoptosis-linked gene 2 protein , probable calcium-binding protein ALG-2 , ALG-257 , PMP41

GENE ID SPECIES
380264 Xenopus laevis
393925 Danio rerio
723039 Macaca mulatta
10016 Homo sapiens
18570 Mus musculus
420988 Gallus gallus
609549 Canis lupus familiaris
100125927 Bos taurus
308061 Rattus norvegicus
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