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anti-Prolylcarboxypeptidase (PRCP) Antibodies

The protein encoded by PRCP is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. Additionally we are shipping Prolylcarboxypeptidase Kits (43) and Prolylcarboxypeptidase Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRCP 649 P13497
PRCP 72461 Q7TMR0
PRCP 293118  
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Top anti-Prolylcarboxypeptidase Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in MicroplateReader by 450nm. Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in Microplate Reader by 450nm 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB PRCP Antibody (N-term) (ABIN657308) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$379.50
Details

PRCP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine) ,


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Rat (Rattus) , ,


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More Antibodies against Prolylcarboxypeptidase Interaction Partners

Human Prolylcarboxypeptidase (PRCP) interaction partners

  1. Studies indicate crosstalk between Notch receptor and Wnt protein, Hedgehog protein, hypoxia and transforming growth factor beta (TGFbeta)/bone morphogenetic protein (BMP) pathways.

  2. study thus highlights the severe and progressive nature of BMP1 (show BMP1 Antibodies)-associated OI in adults and broadens insights into the functional consequences of BMP1/mTLD-deficiency on ECM (show MMRN1 Antibodies) organization.

  3. Data indicate that BMP-1 (show BMP1 Antibodies) can simultaneously trigger matrix assembly and boost the synthesis of matrix proteins via a direct effect on growth factors in the contexts of development, growth and tissue repair. [review]

  4. The decrease in PRCP levels in the first 24 h after stroke onset is associated with stroke severity and an unfavourable short-term stroke outcome

  5. Two novel variants in the BMP1 (show BMP1 Antibodies) gene: c.808A>G and c.1297G>T care associated with osteogenesis imperfecta (show COL1A2 Antibodies).

  6. Frequent bone fracture in children is cause by BMP1 (show BMP1 Antibodies)-1 deficiency.

  7. mutations of the DSP-PP P4 to P4' cleavage site can block, impair or accelerate dentin sialoprotein phosphophoryn cleavage, and suggest that its Bone morphogenic protein 1 cleavage site is conserved in order to regulate its cleavage efficiency

  8. PRCP1 interacts with plasma kallikrein (show KLKB1 Antibodies) (PK) at multiple sites for PK activation.

  9. High BMP1 (show BMP1 Antibodies) expression is associated with type-1 diabetes.

  10. Loss of bone morphogenetic protein is associated with prostate cancer.

Mouse (Murine) Prolylcarboxypeptidase (PRCP) interaction partners

  1. This study demonistrated that PRCP gene is broadly expressed in the brain.

  2. PRCP regulates cell growth, angiogenesis, and the response to vascular injury

  3. ACE2 (show ACE2 Antibodies) metabolizes ANG II (show AGT Antibodies) in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.

  4. PRCP is an important regulator of energy and glucose homeostasis since its deletion significantly improves metabolic parameters in mice exposed to both standard chow diet and high-fat diet

  5. analysis of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors

  6. This study showed that PRCP mutant mice have a significant decrease in fat mass, although an increase in lean mass was also observed; reduced leptin (show LEP Antibodies) levels and increased energy expenditure were also found.

  7. Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis.

  8. PRCP is an important component of melanocortin signaling and weight maintenance via control of active alpha-MSH1-13 levels.

Prolylcarboxypeptidase (PRCP) Antigen Profile

Protein Summary

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with PRCP

  • prolylcarboxypeptidase (angiotensinase C) (PRCP) antibody
  • prolylcarboxypeptidase (angiotensinase C) (prcp) antibody
  • prolylcarboxypeptidase (AaeL_AAEL005521) antibody
  • prolylcarboxypeptidase (CpipJ_CPIJ006123) antibody
  • prolylcarboxypeptidase (CpipJ_CPIJ006124) antibody
  • bone morphogenetic protein 1 (BMP1) antibody
  • prolylcarboxypeptidase (angiotensinase C) (Prcp) antibody
  • 2510048K03Rik antibody
  • 2610104A14Rik antibody
  • AI451719 antibody
  • HUMPCP antibody
  • MGC145178 antibody
  • OI13 antibody
  • PCOLC antibody
  • PCP antibody
  • PCP2 antibody
  • TLD antibody

Protein level used designations for PRCP

prolylcarboxypeptidase , mammalian tolloid protein , procollagen C-endopeptidase , procollagen C-proteinase , lysosomal Pro-X carboxypeptidase , proline carboxypeptidase , angiotensinase C , lysosomal carboxypeptidase C , prolylcarboxypeptidase isoform 1 preproprotein

GENE ID SPECIES
100061830 Equus caballus
780095 Xenopus (Silurana) tropicalis
5579822 Aedes aegypti
6038068 Culex quinquefasciatus
6038069 Culex quinquefasciatus
649 Homo sapiens
72461 Mus musculus
5547 Homo sapiens
476788 Canis lupus familiaris
534927 Bos taurus
293118 Rattus norvegicus
100734342 Cavia porcellus
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