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PROM2 encodes a member of the prominin family of pentaspan membrane glycoproteins. Additionally we are shipping Prominin 2 Antibodies (78) and many more products for this protein.
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Prom2 protrusions primarily localize to lipid rafts and recruit cholesterol into protrusions and away from caveolae, leading to increased phosphorylation of caveolin-1 (show CAV1 Proteins), which inhibits Cdc42 (show CDC42 Proteins)-dependent endocytosis
Data show the distribution and subcellular localization of prominin-2 within the kidney in situ and its release into the urine.
The PROM2 gene was shown to effectively separate these two tumor(chromophobe renal cell carcinoma (show MOK Proteins) (RCC (show XRCC1 Proteins)) and benign oncocytoma) groups by quantitative reverse transcription-PCR using fresh tissue samples, with similar trends seen on formalin-fixed tissues.
Prominin-2 is widely and abundantly expressed along the epithelia of various segments of the adult male genitourinary tract.
prominin-2, another protein in the same family as CD133/prominin-1, may not play an important functional role in the growth of human glioma and hepatocellular carcinoma cells
Data show the distribution and subcellular localization of prominin-2 within the kidney in situ.
These data show that all the characteristics of prominin-1 are shared by prominin-2, which is in agreement with a possible redundancy in their role as potential organizers of plasma membrane protrusions.
expression Prominin-2, in the three pairs of major salivary glands, i.e., submandibular-, major sublingual-, and parotid glands in adult mice.
This gene encodes a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains. Alternative splicing results in multiple transcript variants.
, prominin 3
, prominin-like 3
, prominin-like protein 2
, prominin-related protein
, testosterone-regulated prominin-related protein