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PAAF1 encodes a WD repeat-containing protein involved in regulation of association of proteasome components. Additionally we are shipping Proteasomal ATPase-Associated Factor 1 Proteins (5) and Proteasomal ATPase-Associated Factor 1 Kits (3) and many more products for this protein.
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Human Polyclonal PAAF1 Primary Antibody for IHC (p), WB - ABIN651253
Lassot, Latreille, Rousset, Sourisseau, Linares, Chable-Bessia, Coux, Benkirane, Kiernan: The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms. in Molecular cell 2007
Show all 2 references for ABIN651253
These results show that intracellular levels of Spt6 (show SUPT6H Antibodies) are fine-tuned by PAAF1 and proteasome, which is required for HIV-1 transcription and extends to cellular genes implicated in cancer.
Proteasomal ATPase-associated factor 1 (PAAF1) functions as a negative regulator of the proteasome by controlling the assembly/disassembly of the proteasome.
This gene encodes a WD repeat-containing protein involved in regulation of association of proteasome components. During HIV infection, the encoded protein is thought to promote provirus transcription through recruitment of the 19S regulatory complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
proteasomal ATPase-associated factor 1
, gene 16
, WD repeat domain 71
, WD repeat-containing protein 71