You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Protein AF-10 (MLLT10) Antibodies

MLLT10 encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Additionally we are shipping Protein AF-10 Proteins (3) and Protein AF-10 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MLLT10 8028 P55197
MLLT10 17354 O54826
MLLT10    
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Protein AF-10 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO205/Jurkat cells, using AF1... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-MLLT10 Pab (ABIN390125) in Jurkat cell l... Formalin-fixed and paraffin-embedded human testis tissue reacted with ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, WB AP20116PU-N AF10 antibody staining of Rat Testis lysate at 1 µg/ml (RI... 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of MLLT10 (ABIN1882102) in K562 cell line lysate... Western blot analysis of MLLT10 (ABIN1882102) in K562 cell line lysate... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Rat Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SCC xeno... WB Image Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE AF1... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot (WB) analysis of AF-10 antibody in extracts from COLO205 ... Western blot (WB) analysis of AF-10 antibody at 1/500 dilution.Lane 1:... 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details

MLLT10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Mouse (Murine) , , ,
,
Rat (Rattus) , , ,
,

Top referenced anti-Protein AF-10 Antibodies

  1. Human Polyclonal MLLT10 Primary Antibody for IF, WB - ABIN1882102 : Cai, Gao, Sheng, Miao, Cui, Wang, Zong, Koide: Characterization and potential function of a novel testis-specific nucleoporin BS-63. in Molecular reproduction and development 2002 (PubMed)
    Show all 6 references for ABIN1882102

  2. Human Polyclonal MLLT10 Primary Antibody for EIA, IHC (p) - ABIN358670 : Perrin, Bloyer, Ferraz, Agrawal, Sinha, Dura: The leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusions. in Molecular and cellular biology 2002 (PubMed)
    Show all 4 references for ABIN358670

  3. Human Polyclonal MLLT10 Primary Antibody for ELISA, WB - ABIN1533784 : Chaplin, Ayton, Bernard, Saha, Della Valle, Hillion, Gregorini, Lillington, Berger, Young: A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia. in Blood 1995 (PubMed)
    Show all 3 references for ABIN1533784

  4. Cow (Bovine) Polyclonal MLLT10 Primary Antibody for EIA, WB - ABIN498029 : Lin, Kakadia, Chen, Li, Deshpande, Buske, Zhang, Zhang, Xu, Bohlander: Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias. in Blood 2009 (PubMed)
    Show all 2 references for ABIN498029

  5. Human Polyclonal MLLT10 Primary Antibody for IHC (p), WB - ABIN390125 : Roll, Zattara-Cannoni, Bustos-Bernard, Curtillet, Michel, Vagner-Capodano: Molecular and fluorescence in situ hybridization analysis of a 10;11 rearrangement in a case of infant acute monocytic leukemia. in Cancer genetics and cytogenetics 2002 (PubMed)
    Show all 2 references for ABIN390125

More Antibodies against Protein AF-10 Interaction Partners

Human Protein AF-10 (MLLT10) interaction partners

  1. The PZP (show PZP Antibodies) domain of AF10 senses unmodified H3K27 to regulate DOT1L (show DOT1L Antibodies)-mediated methylation of H3K79.

  2. we report that variants at the MLLT10 locus are unlikely to alter risk of glioma, and they have no prognostic value among patients with high-grade tumors (glioblastoma).

  3. Results provide evidence that transformation driven by MLL (show MLL Antibodies) fusions as well as the recurrent AML (show RUNX1 Antibodies)-associated NUP98 (show NUP98 Antibodies)-NSD1 (show NSD1 Antibodies) fusion oncogene (show RAB1A Antibodies) is critically dependent on the ability of AF10 to stimulate DOT1L (show DOT1L Antibodies) activity.

  4. detection of PICALM (show PICALM Antibodies)-MLLT10 fusion transcript occurs in 7% of children with T-lineage ALL and is not associated with a poorer outcome for patients treated with contemporary, intensive chemotherapy

  5. In pediatric T-acute lymphoblastic leukemia, we have identified 2 RNA processing genes, that is, HNRNPH1 (show HNRNPH1 Antibodies)/5q35 and DDX3X (show DDX3X Antibodies)/Xp11.3 as new MLLT10 fusion partners.

  6. results strongly indicate that the differential regulation of these three genes is not due to the break point effect but as a consequence of the CALM/AF10 fusion gene expression, though the mechanism of regulation is not well understood

  7. In leukemia cells, full-length CALM-AF10 localized to the nucleus with no consistent effect on growth factor endocyctosis, and suppressed histone H3 lysine 79 methylation regardless of the presence of clathrin

  8. a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 x 10(-14)) was identified.

  9. FISH analysis in infant AML (show RUNX1 Antibodies)-M5 showed a complex rearrangement between chromosomes 10 and 11, disrupting the MLL (show MLL Antibodies) gene, a paracentric inversion of the 11q13-q23 fragment translocated to 10p12. AF10 was the fusion partner gene of MLL (show MLL Antibodies) in this rearrangement.

  10. ALL1 (show MLL Antibodies) is involved in remodeling, acetylating, deacetylating, and methylating nucleosomes and/or free histones

Mouse (Murine) Protein AF-10 (MLLT10) interaction partners

  1. Results provide evidence that transformation driven by MLL (show MLL Antibodies) fusions as well as the recurrent AML (show RUNX1 Antibodies)-associated NUP98 (show NUP98 Antibodies)-NSD1 (show NSD1 Antibodies) fusion oncogene (show RAB1A Antibodies) is critically dependent on the ability of AF10 to stimulate DOT1L (show DOT1L Antibodies) activity.

  2. During leukemogenesis, CALM-AF10 plays critical roles in the cytoplasm.

  3. In leukemia cells, full-length CALM-AF10 localized to the nucleus with no consistent effect on growth factor endocyctosis, and suppressed histone H3 lysine 79 methylation regardless of the presence of clathrin

  4. further suggest that future approaches to antagonize CALM-AF10-induced transformation should incorporate strategies, which aim at blocking these key domains

  5. conclude that Mllt10/Af10-Dot1l (show DOT1L Antibodies) are essential, largely dedicated activators of Wnt (show WNT2 Antibodies)-dependent transcription, critical for maintenance of intestinal proliferation and homeostasis

Protein AF-10 (MLLT10) Antigen Profile

Protein Summary

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Protein AF-10 (MLLT10) Antibodies

  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10) antibody
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (Mllt10) antibody
  • Af10 antibody
  • B130021D15Rik antibody
  • D630001B22Rik antibody
  • mKIAA4140 antibody

Protein level used designations for anti-Protein AF-10 (MLLT10) Antibodies

ALL1-fused gene from chromosome 10 protein , protein AF-10 , type I AF10 protein , type III AF10 protein , type IV AF10 protein , myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog

GENE ID SPECIES
8028 Homo sapiens
17354 Mus musculus
Selected quality suppliers for anti-Protein AF-10 (MLLT10) Antibodies
Did you look for something else?