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MLLT10 Products

(Protein AF-10 (MLLT10))
This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010].

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Featured MLLT10 Categories

MLLT10 Antibodies

High quality antibodies with extensive validation data.

MLLT10 ELISA Kits

Reliable ELISA kits for a wide range of species.

MLLT10 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MLLT10 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (6)
  • (2)
Cat. No. ABIN1882102
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257326
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN390125
Quantity 400 μL
Datasheet Datasheet

Recommended MLLT10 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648079
Quantity 96 tests
Datasheet Datasheet

Recommended MLLT10 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311015
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3088704
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3131769
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MLLT10 products

Benedikt, Baltruschat, Scholz, Bursen, Arrey, Meyer, Varagnolo, Müller, Karas, Dingermann, Marschalek: "The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures." in: Leukemia, Vol. 25, Issue 1, pp. 135-44, (2011) (PubMed).

Lin, Kakadia, Chen, Li, Deshpande, Buske, Zhang, Zhang, Xu, Bohlander: "Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias." in: Blood, Vol. 114, Issue 3, pp. 651-8, (2009) (PubMed).

Cai, Gao, Sheng, Miao, Cui, Wang, Zong, Koide: "Characterization and potential function of a novel testis-specific nucleoporin BS-63." in: Molecular reproduction and development, Vol. 61, Issue 1, pp. 126-34, (2002) (PubMed).

Perrin, Bloyer, Ferraz, Agrawal, Sinha, Dura: "The leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusions." in: Molecular and cellular biology, Vol. 23, Issue 1, pp. 119-30, (2002) (PubMed).

Roll, Zattara-Cannoni, Bustos-Bernard, Curtillet, Michel, Vagner-Capodano: "Molecular and fluorescence in situ hybridization analysis of a 10;11 rearrangement in a case of infant acute monocytic leukemia." in: Cancer genetics and cytogenetics, Vol. 135, Issue 2, pp. 187-91, (2002) (PubMed).

Nakamura, Mori, Tada, Krajewski, Rozovskaia, Wassell, Dubois, Mazo, Croce, Canaani: "ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation." in: Molecular cell, Vol. 10, Issue 5, pp. 1119-28, (2002) (PubMed).

Debernardi, Bassini, Jones, Chaplin, Linder, de Bruijn, Meese, Young: "The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex." in: Blood, Vol. 99, Issue 1, pp. 275-81, (2001) (PubMed).

Synonyms and alternative names related to MLLT10

MLLT10, histone lysine methyltransferase DOT1L cofactor (MLLT10), myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 (Mllt10), AF10, Af10, B130021D15Rik, D630001B22Rik, mKIAA4140

Protein level used designations for MLLT10

  • ALL1-fused gene from chromosome 10 protein
  • protein AF-10
  • type I AF10 protein
  • type III AF10 protein
  • type IV AF10 protein
  • myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog
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