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anti-Protein Disulfide Isomerase Family A, Member 6 (PDIA6) Antibodies

Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 [PubMed 7590364]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PDIA6 Proteins (16) and PDIA6 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDIA6 71853 Q922R8
PDIA6 10130 Q15084
PDIA6 286906 Q63081
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Top anti-PDIA6 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-PDIA6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-PDIA6 antibody (ARP52103_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PDIA6 Antibody (Center) in NCI-H460, MCF-7, A2058 cell line lysates (35ug/lane). PDIA6 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB (LEFT) Western blot analysis of PDIA6 antibody (Center K159) in Y79 cell line lysates (35ug/lane). PDIA6 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of PDIA6 antibody (Center K159) in mouse stomach tissue lysates (35ug/lane). PDIA6 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated IP, IHC, WB WB Suggested Anti-PDIA6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate IP Suggested AntiPDIA6 Antibody Positive Control: NT2 CELL/BRAIN TISSUE 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PDIA6 Antibody (Center D251) (ABIN390609) in NCI-H460, MCF-7, A2058 cell line lysates (35 µg/lane). PDIA6 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with PDIA6 Antibody (Center D251), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PDIA6 antibody (Center K159) (ABIN390608) in Y79 cell line lysates (35 µg/lane). PDIA6 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of PDIA6 antibody (Center K159) (ABIN390608) in mouse stomach tissue lysates (35 µg/lane). PDIA6 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of PDIA6 expression in transfected 293T cell line by PDIA6 monoclonal antibody (M04), clone 3B4.Lane 1: PDIA6 transfected lysate(48.1 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged PDIA6 is 3 ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$388.08
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-PDIA6 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959009 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

PDIA6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)
,

Human ,
, ,
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Rat (Rattus)
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Top referenced anti-PDIA6 Antibodies

  1. Cow (Bovine) Polyclonal PDIA6 Primary Antibody for IHC, WB - ABIN2784776 : Kaiser, Yim, Chow, Gonzalez, Dai, Mann, Strong, Groh, Spies: Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands. in Nature 2007 (PubMed)

  2. Human Monoclonal PDIA6 Primary Antibody for ELISA, WB - ABIN2752398 : Lee, Min Kim, Dotimas, Li, Feener, Baldus, Myers, Chutkow, Patwari, Yoshioka, Lee: Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress. in EMBO molecular medicine 2014 (PubMed)

  3. Human Polyclonal PDIA6 Primary Antibody for EIA, WB - ABIN453260 : Hayano, Kikuchi: Cloning and sequencing of the cDNA encoding human P5. in Gene 1995 (PubMed)

More Antibodies against PDIA6 Interaction Partners

Mouse (Murine) Protein Disulfide Isomerase Family A, Member 6 (PDIA6) interaction partners

  1. one additional protein, namely P58 (show CDK11B Antibodies)(IPK), specifically precipitated with Akita proinsulin (show INS Antibodies) and approximately ten fold more PDIA6, but not other PDI (show PDIA3 Antibodies) family members, was bound to Akita proinsulin (show INS Antibodies). The latter suggests that PDIA6 may act as a key reductase

  2. these findings demonstrated that ER Ca2 (show CA2 Antibodies)+, PDIA6, IRE1alpha (show ERN1 Antibodies), and miR (show MLXIP Antibodies)-322 function in a dynamic feedback loop modulating the UPR under conditions of disrupted ER Ca2 (show CA2 Antibodies)+ homeostasis.

  3. By facilitating disulfide bond formation, and enhanced ER protein folding, PDIA6 may contribute to the protective effects of ATF6 (show ATF6 Antibodies) in the ischemic mouse heart.

Human Protein Disulfide Isomerase Family A, Member 6 (PDIA6) interaction partners

  1. ACE (show ACE Antibodies) and PDIA6 were identified as potential HSPA2 (show HSPA2 Antibodies)-interacting proteins; this assemblage resides in membrane raft microdomains located in the peri (show PLIN1 Antibodies)-acrosomal region of the sperm head.

  2. Restoration of miR (show MLXIP Antibodies)-127-3p and miR (show MLXIP Antibodies)-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1 (show UBXN11 Antibodies), GLE1 (show GLE1 Antibodies) and PDIA6.

  3. PDIA3 (show PDIA3 Antibodies) and PDIA6 gene expression is a neoplasm aggressiveness marker in primary ductal breast cancer.

  4. CDDP-resistant non-small lung cancer cells undergo profound remodeling of their endoplasmic reticulum (ER) proteome (>80 proteins identified by proteomics) and exhibit a dramatic overexpression of two protein disulfide isomerases, PDIA4 (show PDIA4 Antibodies) and PDIA6.

  5. Txnip (show TXNIP Antibodies) is located in the endoplasmic reticulum and interacts with endogenous PDIA6. Txnip (show TXNIP Antibodies) increases PDI (show PADI1 Antibodies) activity.

  6. levels of expression of ERp5 and GRP78 (show HSPA5 Antibodies) correlated with the level of expression of membrane-bound MICA (show MICA Antibodies) in chronic lymphocytic leukemia patients.

  7. Data show that the lymph node (LN) stroma displayed in situ high levels of transcription and expression of the disulfide-isomerase ERp5 and of the disintegrin-metalloproteinase (show ADAM17 Antibodies) ADAM10 (show ADAM10 Antibodies), able to shed the ligands for NKG2D (NKG2D (show KLRK1 Antibodies)-L) from the cell membrane.

  8. P5 forms a non-covalent complex with immunoglobulin heavy chain binding protein (BiP (show HSPA5 Antibodies)) and shows specificity towards BiP (show GDF10 Antibodies) client proteins.

  9. observed to have peptide-binding ability, and chaperone activity was confirmed with rhodanese (show TST Antibodies) and citrate synthase (show CS Antibodies) as substrates, but not with D-glyceraldehyde-3-phosphate dehydrogenase (show GAPDH Antibodies), showing substrate specificity with respect to chaperone activity

  10. ERP5 regulates the binding of fibrinogen, cell-surface exposure of P-selectin (show SELP Antibodies), and coassociation of beta 3 integrin in stimulated platelets.

PDIA6 Antigen Profile

Protein Summary

Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995

Gene names and symbols associated with PDIA6

  • protein disulfide isomerase A6 (LOC100346580) antibody
  • protein disulfide isomerase associated 6 (Pdia6) antibody
  • protein disulfide isomerase family A, member 6 (PDIA6) antibody
  • protein disulfide isomerase family A, member 6 (Pdia6) antibody
  • protein disulfide isomerase family A, member 6 (pdia6-a) antibody
  • 1700015E05Rik antibody
  • AL023058 antibody
  • C77895 antibody
  • CaBP1 antibody
  • CaBP5 antibody
  • erp5 antibody
  • P5 antibody
  • pdi-p5 antibody
  • pdia6 antibody
  • pdip5 antibody
  • txndc7 antibody

Protein level used designations for PDIA6

protein disulfide isomerase-related protein , protein disulfide-isomerase A6 , thioredoxin domain containing 7 , thioredoxin domain-containing protein 7 , ER protein 5 , endoplasmic reticulum protein 5 , protein disulfide isomerase P5 , protein disulfide isomerase-associated 6 , thioredoxin domain containing 7 (protein disulfide isomerase) , calcium-binding protein 1 , protein disulfide isomerase A6 , protein disulfide isomerase associated 6

GENE ID SPECIES
100346580 Oryctolagus cuniculus
71853 Mus musculus
10130 Homo sapiens
286906 Rattus norvegicus
421940 Gallus gallus
475668 Canis lupus familiaris
100499564 Sus scrofa
613927 Bos taurus
446478 Xenopus laevis
100173470 Pongo abelii
Selected quality suppliers for anti-PDIA6 (PDIA6) Antibodies
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