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Protein Disulfide Isomerase Family A, Member 6 Proteins (PDIA6)

Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 [PubMed 7590364]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PDIA6 Antibodies (48) and PDIA6 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDIA6 71853 Q922R8
PDIA6 10130 Q15084
Rat PDIA6 PDIA6 286906 Q63081
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Top PDIA6 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 9 to 11 Days
$598.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$3,035.21
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$3,169.83
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,173.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$385.00
Details

PDIA6 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, ,

Top referenced PDIA6 Proteins

  1. Human PDIA6 Protein expressed in Escherichia coli (E. coli) - ABIN667257 : Jordan, Stevens, Hubbard, Barrett, Sage, Authi, Gibbins: A role for the thiol isomerase protein ERP5 in platelet function. in Blood 2005 (PubMed)
    Show all 2 references for ABIN667257

More Proteins for Protein Disulfide Isomerase Family A, Member 6 (PDIA6) Interaction Partners

Mouse (Murine) Protein Disulfide Isomerase Family A, Member 6 (PDIA6) interaction partners

  1. one additional protein, namely P58 (show CDK11B Proteins)(IPK), specifically precipitated with Akita proinsulin (show INS Proteins) and approximately ten fold more PDIA6, but not other PDI (show PDIA3 Proteins) family members, was bound to Akita proinsulin (show INS Proteins). The latter suggests that PDIA6 may act as a key reductase

  2. these findings demonstrated that ER Ca2 (show CA2 Proteins)+, PDIA6, IRE1alpha (show ERN1 Proteins), and miR (show MLXIP Proteins)-322 function in a dynamic feedback loop modulating the UPR under conditions of disrupted ER Ca2 (show CA2 Proteins)+ homeostasis.

  3. By facilitating disulfide bond formation, and enhanced ER protein folding, PDIA6 may contribute to the protective effects of ATF6 (show ATF6 Proteins) in the ischemic mouse heart.

Human Protein Disulfide Isomerase Family A, Member 6 (PDIA6) interaction partners

  1. ACE (show ACE Proteins) and PDIA6 were identified as potential HSPA2 (show HSPA2 Proteins)-interacting proteins; this assemblage resides in membrane raft microdomains located in the peri (show PLIN1 Proteins)-acrosomal region of the sperm head.

  2. Restoration of miR (show MLXIP Proteins)-127-3p and miR (show MLXIP Proteins)-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1 (show UBXN11 Proteins), GLE1 (show GLE1 Proteins) and PDIA6.

  3. PDIA3 (show PDIA3 Proteins) and PDIA6 gene expression is a neoplasm aggressiveness marker in primary ductal breast cancer.

  4. CDDP-resistant non-small lung cancer cells undergo profound remodeling of their endoplasmic reticulum (ER) proteome (>80 proteins identified by proteomics) and exhibit a dramatic overexpression of two protein disulfide isomerases, PDIA4 and PDIA6.

  5. Txnip (show TXNIP Proteins) is located in the endoplasmic reticulum and interacts with endogenous PDIA6. Txnip (show TXNIP Proteins) increases PDI (show PADI1 Proteins) activity.

  6. levels of expression of ERp5 and GRP78 (show HSPA5 Proteins) correlated with the level of expression of membrane-bound MICA (show MICA Proteins) in chronic lymphocytic leukemia patients.

  7. Data show that the lymph node (LN) stroma displayed in situ high levels of transcription and expression of the disulfide-isomerase ERp5 and of the disintegrin-metalloproteinase (show ADAM17 Proteins) ADAM10 (show ADAM10 Proteins), able to shed the ligands for NKG2D (NKG2D (show KLRK1 Proteins)-L) from the cell membrane.

  8. P5 forms a non-covalent complex with immunoglobulin heavy chain binding protein (BiP (show HSPA5 Proteins)) and shows specificity towards BiP (show GDF10 Proteins) client proteins.

  9. observed to have peptide-binding ability, and chaperone activity was confirmed with rhodanese (show TST Proteins) and citrate synthase (show CS Proteins) as substrates, but not with D-glyceraldehyde-3-phosphate dehydrogenase (show GAPDH Proteins), showing substrate specificity with respect to chaperone activity

  10. ERP5 regulates the binding of fibrinogen, cell-surface exposure of P-selectin (show SELP Proteins), and coassociation of beta 3 integrin in stimulated platelets.

PDIA6 Protein Profile

Protein Summary

Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995

Gene names and symbols associated with PDIA6

  • protein disulfide isomerase A6 (LOC100346580)
  • protein disulfide isomerase associated 6 (Pdia6)
  • protein disulfide isomerase family A, member 6 (PDIA6)
  • protein disulfide isomerase family A, member 6 (Pdia6)
  • protein disulfide isomerase family A, member 6 (pdia6-a)
  • 1700015E05Rik protein
  • AL023058 protein
  • C77895 protein
  • CaBP1 protein
  • CaBP5 protein
  • erp5 protein
  • P5 protein
  • pdi-p5 protein
  • pdia6 protein
  • pdip5 protein
  • txndc7 protein

Protein level used designations for PDIA6

protein disulfide isomerase-related protein , protein disulfide-isomerase A6 , thioredoxin domain containing 7 , thioredoxin domain-containing protein 7 , ER protein 5 , endoplasmic reticulum protein 5 , protein disulfide isomerase P5 , protein disulfide isomerase-associated 6 , thioredoxin domain containing 7 (protein disulfide isomerase) , calcium-binding protein 1 , protein disulfide isomerase A6 , protein disulfide isomerase associated 6

GENE ID SPECIES
100346580 Oryctolagus cuniculus
71853 Mus musculus
10130 Homo sapiens
286906 Rattus norvegicus
421940 Gallus gallus
475668 Canis lupus familiaris
100499564 Sus scrofa
613927 Bos taurus
446478 Xenopus laevis
100173470 Pongo abelii
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