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Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Proteins (PPP1R14A)

The protein encoded by PPP1R14A belongs to the protein phosphatase 1 (PP1) inhibitor family. Additionally we are shipping Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Antibodies (43) and Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPP1R14A 94274 Q96A00
PPP1R14A 114004 Q99MC0
PPP1R14A 68458 Q91VC7
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Top Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$4,009.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

PPP1R14A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Proteins

  1. Human PPP1R14A Protein expressed in Escherichia coli (E. coli) - ABIN667711 : Eto, Senba, Morita, Yazawa: Molecular cloning of a novel phosphorylation-dependent inhibitory protein of protein phosphatase-1 (CPI17) in smooth muscle: its specific localization in smooth muscle. in FEBS letters 1997 (PubMed)
    Show all 3 references for ABIN667711

More Proteins for Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Interaction Partners

Zebrafish Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) interaction partners

  1. Hoxb1b is likely to directly regulate ppp1r14al expression in rhombomere 4. Furthermore, ppp1r14al is essential for establishment of the earliest hindbrain signaling-center in rhombomere 4 by regulating expression of fgf3 (show FGF3 Proteins).

Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) interaction partners

  1. CPI-17 has a role in restoring skin homoeostasis in cutaneous field of cancerization lesions

  2. analysis of the interaction between plakoglobin (show JUP Proteins) and CPI-17, which is affected by the phosphorylation status of CPI-17 in human lung microvascular endothelial cells

  3. The N-terminal 21-residue tail domain of CPI-17 is necessary for nuclear localization. Phospho-mimetic Asp (show ASIP Proteins)-substitution of CPI-17 at Ser12 attenuates the nuclear import.

  4. The study characterized the CPI-17 promoter and identified binding sites for GATA-6 (show GATA6 Proteins) and nuclear factor kappa B (NF-kappaB (show NFKB1 Proteins)).

  5. a novel signaling cascade that links RhoA (show RHOA Proteins)-mediated calcium sensitivity to MEF2 (show MEF2A Proteins)-dependent myocardin expression in VSMCs through a mechanism involving p38 MAPK (show MAPK14 Proteins), PP1alpha (show PPP1CA Proteins), and CPI-17.

  6. RACK1 (show GNB2L1 Proteins) may play a role in PKC (show PRRT2 Proteins)/CPI-17 signaling pathway.

  7. cAMP/PKA regulates the endothelial barrier via inhibition of the contractile machinery, mainly by the activation of MLCP via inhibition of CPI-17 and RhoA (show RHOA Proteins)/Rock.

  8. mapped to chromosome 19q13.13-q13.2

  9. CPI-17 binds directly to protein kinase C and casein kinase I (show CSNK1D Proteins).

  10. importance of PKC (show PRRT2 Proteins)/CPI-17-mediated pathway in histamine-triggered cytoskeletal rearrangements leading to lung microvascular barrier compromise.

Mouse (Murine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) interaction partners

  1. Enhanced vasorelaxation in early endotoxemia is mediated by redox signaling through PKG-1alpha but in later endotoxemia by myosin phosphatase isoform shifts enhancing sensitivity to NO/cGMP as well as smooth muscle atrophy.

  2. The study characterized the CPI-17 promoter and identified binding sites for GATA-6 (show GATA6 Proteins) and nuclear factor kappa B (NF-kappaB (show NFKB1 Proteins)).

  3. a novel signaling cascade that links RhoA (show RHOA Proteins)-mediated calcium sensitivity to MEF2 (show MEF2C Proteins)-dependent myocardin expression in VSMCs through a mechanism involving p38 MAPK (show MAPK14 Proteins), PP1alpha (show PPP1CA Proteins), and CPI-17.

  4. Data suggest that CPI-17 and both conventional and novel PKC isozymes contribute to the phasic and tonic contractile components of BALB/c colonic circular smooth muscle.

  5. Organ-specific mechanisms involving MYPT1 (show PPP1R12A Proteins), M-RIP, and CPI-17 are critical to regulating basal LC20 (show MYL9 Proteins) phosphorylation in gastrointestinal smooth muscles.

  6. calcium-independent phospholipase A2beta has a role in high glucose-induced activation of RhoA (show RHOA Proteins), Rho kinase (show ROCK2 Proteins), and CPI-17 in cultured vascular smooth muscle cells and vascular smooth muscle hypercontractility in diabetic animals

  7. distribution of mouse and rat PPP1R14A was more specific and different from that of humans

  8. concluded that actions downstream of cGMP/PKG (show PRKG1 Proteins) can reverse PKC-mediated phosphorylation of CPI-17 and Ca(2 (show CA2 Proteins)+) sensitization in smooth muscle

  9. findings suggest that CPI-17 was downregulated during intestinal inflammation and that TNF-alpha (show TNF Proteins) plays a central role in this process. Downregulation of CPI-17 may play a role in motility impairments in inflammation.

  10. CPI-17 expression is reversibly controlled in response to the phenotype transition of smooth muscle cells that restricts the signal to differentiated smooth muscle cells and particular cell types.

Pig (Porcine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) interaction partners

  1. This study examined the protein expression and spatial-temporal distribution of PKCalpha (show PKCa Proteins) and CPI-17 in intact smooth muscle tissues.

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with PPP1R14A

  • protein phosphatase 1, regulatory (inhibitor) subunit 14A (ppp1r14a)
  • protein phosphatase 1, regulatory (inhibitor) subunit 14Aa (ppp1r14aa)
  • protein phosphatase 1, regulatory (inhibitor) subunit 14A (PPP1R14A)
  • protein phosphatase 1, regulatory (inhibitor) subunit 14A (Ppp1r14a)
  • 1110001M11Rik protein
  • CPI-17 protein
  • Cpi17 protein
  • im:7147597 protein
  • MGC81874 protein
  • PPP1INL protein
  • PPP1R14A protein
  • zgc:110700 protein

Protein level used designations for PPP1R14A

protein phosphatase 1, regulatory (inhibitor) subunit 14A , protein phosphatase 1 regulatory subunit 14A , 17 kDa PKC-potentiated inhibitory protein of PP1 , 17-KDa protein , 17-kDa PKC-potentiated inhibitory protein of PP1 , PKC-potentiated inhibitory protein of PP1 , protein kinase C-potentiated inhibitor protein of 17 kDa , CPI-17

GENE ID SPECIES
447728 Xenopus laevis
493331 Xenopus (Silurana) tropicalis
550561 Danio rerio
612579 Canis lupus familiaris
615348 Bos taurus
641304 Ovis aries
747250 Pan troglodytes
94274 Homo sapiens
114004 Rattus norvegicus
68458 Mus musculus
397610 Sus scrofa
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