anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) Antibodies

PPP1R1B encodes a bifunctional signal transduction molecule. Additionally we are shipping Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Kits (11) and Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPP1R1B 360616 Q6J4I0
PPP1R1B 84152 Q9UD71
PPP1R1B 19049 Q60829
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Antibodies at antibodies-online.com

Showing 10 out of 218 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of DARPP32 (pT75) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of DARPP32 (pT75) expression in MDA-MB-361 (A), SHSY5Y (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$575.00
Details
Mouse Mouse Un-conjugated IF, WB Western blot analysis of DARPP-32 on rat brain lysate. Lane 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of DARPP-32 . 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Rabbit Un-conjugated IF 0.1 mL Log in to see 6 to 8 Days
$368.50
Details
Human Rabbit Un-conjugated IHC (p), IHC, WB Detection of DARPP protein in rat hippocampal lysate using ABIN152638. Immunohistochemistry: DARPP-32 Antibody [ABIN152638] - Immunochemical staining of cultured CD1 mouse striatal cells showing specific labeling of DARPP-32 in green and Tuj1 in red. Cells and photo courtesy of QBMCellScience. 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$430.10
Details
Human Mouse Un-conjugated FACS, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$430.10
Details
Human Rabbit Un-conjugated IHC (p), WB DARPP32 was detected in paraffin-embedded sections of rat intestine tissues using rabbit anti- DARPP32 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method Western blot analysis of DARPP32 expression in rat brain extract (lane 1), SW620 whole cell lysates (lane 2), 22RV1 whole cell lysates (lane 3) and HELA whole cell lysates (lane 4). DARPP32 at 34KD, 39KD was detected using rabbit anti- DARPP32 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB Immunolabeling of rat caudate lysates prepared from caudate slices that had been incubated in the absence and presence of okadaic acid.  The labeling by the antibody to DARPP-32 Thr75 is markedly increased by the okadaic acid treatment. Western Blot: DARPP32 [p Thr75] Antibody [ABIN152574] - Analysis of rat caudate lysate showing specific immunolabeling of the ~32k DARPP-32 phosphorylated at Thr75 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase). The blot is identical to the control except that it was incubated (1200 units for 30 min) before being exposed to the Anti-Thr75 DARPP-32. The immunolabeling is completely eliminated by treatment. 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB L1 mouse liver lysates L2 mouse heart carcinoma lysates probed with Anti Phospho-DARPP32(Thr34) Polyclonal Antibody, Unconjugated (ABIN684388) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 32kD. Observed band size: 32kD 100 μL Log in to see 3 to 7 Days
$317.90
Details

PPP1R1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) , , , ,
, , ,
,
, , , , , , , , , , , , ,
Human , , , ,
, , ,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , , , ,
, , , ,
,
, , , , , , , , , , , , ,

Top referenced anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Antibodies

  1. Human Polyclonal PPP1R1B Primary Antibody for WB - ABIN152574 : Han, Han, Tiwari, Wen, Zheng: Spatial targeting of type II protein kinase A to filopodia mediates the regulation of growth cone guidance by cAMP. in The Journal of cell biology 2007 (PubMed)
    Show all 10 Pubmed References

  2. Rat (Rattus) Polyclonal PPP1R1B Primary Antibody for WB - ABIN361462 : Napolitano, Bonito-Oliva, Federici, Carta, Errico, Magara, Martella, Nistica: Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Show all 13 Pubmed References

  3. Mouse (Murine) Monoclonal PPP1R1B Primary Antibody for IF, WB - ABIN968572 : Bibb, Snyder, Nishi, Yan, Meijer, Fienberg, Tsai, Kwon, Girault, Czernik, Huganir, Hemmings, Nairn, Greengard: Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. in Nature 2000 (PubMed)
    Show all 5 Pubmed References

  4. Mouse (Murine) Polyclonal PPP1R1B Primary Antibody for IHC, WB - ABIN4304299 : Yabuki, Ohizumi, Yokosuka, Mimaki, Fukunaga: Nobiletin treatment improves motor and cognitive deficits seen in MPTP-induced Parkinson model mice. in Neuroscience 2014 (PubMed)
    Show all 4 Pubmed References

  5. Rat (Rattus) Polyclonal PPP1R1B Primary Antibody for WB - ABIN361463 : Gomez, Midde, Mactutus, Booze, Zhu: Environmental enrichment alters nicotine-mediated locomotor sensitization and phosphorylation of DARPP-32 and CREB in rat prefrontal cortex. in PLoS ONE 2012 (PubMed)
    Show all 9 Pubmed References

  6. Human Polyclonal PPP1R1B Primary Antibody for IHC (p), IHC - ABIN152638 : Shioda, Han, Moriguchi, Fukunaga: Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia. in Journal of neurochemistry 2007 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal PPP1R1B Primary Antibody for ELISA, WB - ABIN1724915 : Hamel, Bouchard, Ferrario, Hassan, Aguilar-Mahecha, Buchanan, Quenneville, Miller, Basik: Both t-Darpp and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers. in Breast cancer research and treatment 2010 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal PPP1R1B Primary Antibody for FACS, ELISA - ABIN1724929 : Kunii, Ikemoto, Wada, Yang, Kusakabe, Suzuki, Niwa: Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study. in Medical molecular morphology 2011 (PubMed)
    Show all 2 Pubmed References

  9. Chicken Polyclonal PPP1R1B Primary Antibody for WB - ABIN2473230 : Coudert, Lissac, Teyssier, Bejat, Magnin, Peyrin, Bene: Preliminary results of nuclear magnetic resonance studies of healthy human saliva. in Magnetic resonance in medicine 1989 (PubMed)
    Show all 2 Pubmed References

  10. Chicken Polyclonal PPP1R1B Primary Antibody for WB - ABIN2473229 : Fienberg, Hiroi, Mermelstein, Song, Snyder, Nishi, Cheramy, OCallaghan, Miller, Cole, Corbett, Haile, Cooper, Onn, Grace, Ouimet, White, Hyman, Surmeier, Girault, Nestler, Greengard: DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B Interaction Partners

Rhesus Monkey Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) interaction partners

  1. DARPP-32 and I-1 were most frequently identified in dendritic shafts, unlike the D1R (show DRD1 Antibodies) and PP1 (show PPYR1 Antibodies) isoforms. Moreover, DARPP-32 and I-1 were only present in approximately 4% and 8% of area 9 pyramidal cell spines, respectively.

Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) interaction partners

  1. Results show that expression of human DARPP-32 protein isoforms depends on the striatal neurodevelopmental stage with t-DARPP being specific for the human adult striatum.

  2. In vivo xenograft models demonstrated that overexpression of DARPP-32 promotes angiogenesis and tumour growth.

  3. This study strongly suggests that inflammation-regulated DARPP-32 constitutes a key component of H. pylori-mediated gastric tumourigenesis.

  4. DARPP-32 is mainly cleaved at Thr (show TRH Antibodies)(153) by calpain and this cleavage of DARPP-32 reduces CREB (show CREB1 Antibodies) phosphorylation via loss of its inhibitory function on PP1 (show PPA1 Antibodies); results suggest a novel mechanism of DARPP-32-CREB (show CREB1 Antibodies) signalling dysregulation in Alzheimer's disease

  5. No significant differences in mRNA expression levels of DRD2 (show DRD2 Antibodies) and DARPP-32 were found among controls, patients with psychotic disorder not otherwise specified, and schizophrenia/schizophreniform disorder.

  6. Striatal function was indexed by a gene coding for DARPP-32, which is densely expressed in the striatum where it is necessary for synaptic plasticity

  7. Findings show that PPP1R1B-STARD3 (show STARD3 Antibodies) fusion transcript has a key role in subsets of gastric cancers through the activation of PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling.

  8. Results suggest that variation in PPP1R1B affects the abundance of the splice variant t-DARPP-32 mRNA and may reflect potential molecular mechanisms implicated in schizophrenia and affective disorders

  9. The immunostaining was more decreased for DARPP-32 than for the morphological changes of striatal neurons in multiple system atrophy.

  10. This study showed that variations in genotypes relevant for DARPP-32 functions are associated more with aging-related impairments in the explicit than the implicit component of sequence learning.

Mouse (Murine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) interaction partners

  1. This study strongly suggests that inflammation-regulated DARPP-32 constitutes a key component of H. pylori-mediated gastric tumourigenesis.

  2. the results suggest that by inducing dephosphorylation of DARPP-32 at Ser (show SIGLEC1 Antibodies)-97 and altering its cytonuclear distribution, glutamate (show GRIN1 Antibodies) may counteract dopamine/D1 receptor (show DRD1 Antibodies)/PKA signaling at multiple cellular levels.

  3. Darpp32 interaction with beta-adducin (show ADD2 Antibodies) may be the molecular pathway by which environmental changes may rapidly alter responsiveness of striatal neurons involved in the reward system.

  4. Results show that Darpp-32 was expressed in normal mouse mammary tissue and in some breast tumors, whereas t-Darpp was found exclusively in mammry tumors.

  5. analysis of cAMP-activated DARPP-32 signalling to the nucleus

  6. Results describe the development of new vascular mouse model with a conditional knockout allele of Tsc1 (show TSC1 Antibodies) with a Darpp32-Cre allele. This mouse displayed accelerated formation of both kidney cystadenomas and paw hemangiosarcomas.

  7. Cannabinoid-stimulated G-protein activity did not differ between DARPP-32 KO and WT mice treated with vehicle or repeated THC.

  8. In this work, the dissected postsynaptic topology of the DARPP-32 phosphoprotein provides strong evidence for a compartmentalized and confined distribution in dendritic spines.

  9. Adenosine AA receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation.

  10. Data suggest that histone deacetylase (show HDAC1 Antibodies) inhibitors inhibit the induction of NGF1A-binding protein (show NAB1 Antibodies) Nab2 (show NAB2 Antibodies) by brain derived neurotrophic factor (BDNF (show BDNF Antibodies)), and thereby the relative induction of dopamine and cyclic AMP-regulated phosphoprotein (show ARPP21 Antibodies), 32 kDa (DARPP-32).

Xenopus laevis Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) interaction partners

  1. Areas of brain and spinal cord that are densely innervated by tyrosine hydroxylase (show TH Antibodies)-immunoreactive fibers display a remarkable immunoreactivity for DARPP-32/ppp1r1b in cell bodies and neuropil.

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) Antigen Profile

Protein Summary

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PPP1R1B

  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (ppp1r1b) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (PPP1R1B) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (LOC100355399) antibody
  • protein phosphatase 1 regulatory subunit 1B-like (LOC100736966) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (Ppp1r1b) antibody
  • AU040756 antibody
  • DARPP-32 antibody
  • DARPP32 antibody

Protein level used designations for PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32) , neuronal phosphoprotein DARPP-32 , protein phosphatase 1 regulatory subunit 1B , protein phosphatase 1, regulatory (inhibitor) subunit 1B , dopamine- and cAMP-regulated neuronal phosphoprotein , dopamine- and cAMP-regulated phosphoprotein DARPP-32 , dopamine and cAMP-regulated neuronal phosphoprotein 32 , DARPP-32 , dopamine and cAMP regulated

GENE ID SPECIES
100124928 Xenopus (Silurana) tropicalis
574203 Macaca mulatta
608394 Canis lupus familiaris
744755 Pan troglodytes
100355399 Oryctolagus cuniculus
100736966 Sus scrofa
360616 Rattus norvegicus
84152 Homo sapiens
19049 Mus musculus
733416 Xenopus laevis
282459 Bos taurus
Selected quality suppliers for anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) Antibodies
Did you look for something else?