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anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) Antibodies

Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. Additionally we are shipping PPP4C Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPP4C 5531 P60510
PPP4C 56420 P97470
PPP4C 171366 Q5BJ92
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Top anti-PPP4C Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PPP4C Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p), WB PPP4C Antibody (Center) (ABIN657678) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the PPP4C antibody detected the PPP4C protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ICC, IHC, WB Western blot detection of Protein Phosphatase 4C antibody in Hela, 293 and Jurkat cell lysates using Protein Phosphatase 4C antibody (1: 1000 diluted).  Predicted band size: 34 kDa.  Observed band size: 34 kDa Immunocytochemistry of HeLa cells using anti- Protein Phosphatase 4C antibody diluted 1: 200. 100 μL Log in to see 8 to 9 Days
$392.86
Details
Cow Goat Un-conjugated EIA, IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with PPP4Cfollowed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with PPP4Cfollowed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Cow Rabbit Un-conjugated IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with PPP4C antibody ABIN214615 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PPP4C antibody ABIN214615 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Cow Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-PPP4C Polyclonal Antibody, Unconjugated (ABIN669261) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric cancer labeled with Anti-PPP4C Polyclonal Antibody, Unconjugated (ABIN669261) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

PPP4C Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PPP4C Antibodies

  1. Cow (Bovine) Polyclonal PPP4C Primary Antibody for WB - ABIN2787719 : Toyo-oka, Mori, Yano, Shiota, Iwao, Goto, Inagaki, Hiraiwa, Muramatsu, Wynshaw-Boris, Yoshiki, Hirotsune: Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation. in The Journal of cell biology 2008 (PubMed)

  2. Dog (Canine) Polyclonal PPP4C Primary Antibody for EIA, IHC (p) - ABIN452428 : Mourtada-Maarabouni, Williams: Protein phosphatase 4 regulates apoptosis, proliferation and mutation rate of human cells. in Biochimica et biophysica acta 2008 (PubMed)

More Antibodies against PPP4C Interaction Partners

Zebrafish Protein Phosphatase 4, Catalytic Subunit (PPP4C) interaction partners

  1. Protein phosphatase 4 cooperates with Smads to promote BMP signaling in dorsoventral patterning of zebrafish embryos

Human Protein Phosphatase 4, Catalytic Subunit (PPP4C) interaction partners

  1. mutual regulatory mechanisms exist between PP4 (show ANXA5 Antibodies) and SAF-A (show HNRNPU Antibodies). Interactions between PP4 (show ANXA5 Antibodies) and SAF-A (show HNRNPU Antibodies) played a role in prometaphase/metaphase transition.

  2. These data suggested a potential role of PP4C in tumor progression.

  3. Stathmin plays an essential role of in Merkel cell polyomavirus small tumor antigen-mediated microtubule destabilization and cell motility and this process is regulated by cellular phosphatase catalytic subunit of protein phosphatase 4.

  4. PP4 (show ANXA5 Antibodies) and Wip1 (show PPM1D Antibodies) are differentially required to counteract the p53 (show TP53 Antibodies)-dependent cell cycle arrest in G1 and G2, by antagonizing early or late p53 (show TP53 Antibodies)-mediated responses, respectively

  5. Results show PP4C as a fostriecin-sensitive phosphatase and demonstrate that the suppression of PP4C triggers mitotic slippage/apoptosis.

  6. Data indicate that the major phosphatase responsible for dephosphorylation of of BAF (show BANF1 Antibodies) Ser (show SIGLEC1 Antibodies)-4 to be protein phosphatase 4 catalytic subunit.

  7. Recombinant gamma-tubulin (show TUBG1 Antibodies) can be phosphorylated by Cdk1 (show CDK1 Antibodies)-cyclin B or Brsk1 (show BRSK1 Antibodies) and dephosphorylated by Ppp4c-R2-R3A in vitro.

  8. PP4c is a key regulator of cortical development that changes the orientation of progenitor division responsible for the transition between symmetric and asymmetric cell division.

  9. Overexpression of PP4C is associated with poor prognosis in patients with stage II pancreatic ductal adenocarcinoma.

  10. PP4R1 (show PPP4R1 Antibodies) and PP4c Cooperate to Catalyze IKK (show CHUK Antibodies) Dephosphorylation

Mouse (Murine) Protein Phosphatase 4, Catalytic Subunit (PPP4C) interaction partners

  1. Thus, serine/threonine phosphatase PP4 (show ANXA5 Antibodies) functions as a novel feedback negative regulator of RNA virus-triggered innate immunity.

  2. Taken together, our results establish a novel role for PP4 (show ANXA5 Antibodies) in CSR (show SCARA3 Antibodies), and reveal crucial functions for PP4 (show ANXA5 Antibodies) in the maintenance of genomic stability, GC formation, and B cell-mediated immune responses.

  3. PP4 (show ANXA5 Antibodies) overexpression was observed to lead to a decreased pACC1Ser79/ACC1 (show ACACA Antibodies) ratio and subsequently an increased intracellular triglyceride content in mouse primary hepatocytes.

  4. Mammalian SMEK/PP4C proteins are involved in the regulation of hepatic glucose metabolism through dephosphorylation of CRTC2 (show CRTC2 Antibodies).

  5. Protein phosphatase 4 has a role in apoptosis.

  6. PP4 is essential for thymocyte development and pre-TCR signaling

  7. PP4 (show ANXA5 Antibodies) negatively regulated LPS (show TLR4 Antibodies)-induced and TRAF6 (show TRAF6 Antibodies)-mediated NF-kappaB (show NFKB1 Antibodies) activation by inhibiting the ubiquitination of TRAF6 (show TRAF6 Antibodies).

PPP4C Antigen Profile

Protein Summary

Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C- PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.

Gene names and symbols associated with PPP4C

  • protein phosphatase 4 (formerly X), catalytic subunit (ppp4c) antibody
  • protein phosphatase 4 (formerly X), catalytic subunit a (ppp4ca) antibody
  • protein phosphatase 4, catalytic subunit (PPP4C) antibody
  • protein phosphatase 4, catalytic subunit (Ppp4c) antibody
  • protein phosphatase 4, catalytic subunit (ppp4c) antibody
  • 1110002D08Rik antibody
  • AU016079 antibody
  • gc:56413 antibody
  • MGC75928 antibody
  • PP4 antibody
  • PP4C antibody
  • PP4C-A antibody
  • PPH3 antibody
  • PPP4 antibody
  • ppp4c antibody
  • Ppx antibody
  • wu:fd05e08 antibody
  • zgc:56413 antibody

Protein level used designations for PPP4C

protein phosphatase 4, catalytic subunit , catalytic subunit , serine/threonine-protein phosphatase 4 catalytic subunit A , PP-X , protein phosphatase 4 (formerly X), catalytic subunit , protein phosphatase X, catalytic subunit , serine/threonine-protein phosphatase 4 catalytic subunit , PP4C , pp4 , protein phosphatase X

GENE ID SPECIES
394540 Xenopus (Silurana) tropicalis
100003080 Danio rerio
5531 Homo sapiens
540398 Bos taurus
56420 Mus musculus
171366 Rattus norvegicus
489947 Canis lupus familiaris
100009163 Oryctolagus cuniculus
432334 Xenopus laevis
100173513 Pongo abelii
Selected quality suppliers for anti-PPP4C (PPP4C) Antibodies
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