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Protein tyrosine Phosphatase, Non-Receptor Type 21 Proteins (PTPN21)

The protein encoded by PTPN21 is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping PTPN21 Antibodies (31) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTPN21 11099 Q16825
PTPN21 24000  
PTPN21 171070 Q62728
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Top PTPN21 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Chicken Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PTPN21 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Rat (Rattus)

More Proteins for Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21) Interaction Partners

Human Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21) interaction partners

  1. Presented data suggest that the transient formation of dynamic PTPD1/EGFR (show EGFR Proteins) signalling complexes strengthens EGF (show EGF Proteins) signalling by promoting the spatial propagation of EGFR (show EGFR Proteins) phosphorylated species

  2. The results that 2 non-synonymous markers in PTPN21 are associated with schizophrenia, further investigation of this locus is warranted.

  3. PTPD1 is a novel component of the endocytic machinery that impacts on EGF receptor (show EGFR Proteins) stability and on growth and motility of bladder cancer cells

  4. PTPD1 is a component of a multivalent scaffold complex nucleated by FAK (show PTK2 Proteins) at specific intracellular sites

  5. In colorectal tumors, microsatellite repeats mutation rates are higher than the mean mutation frequency; the highest mutation frequency among 16 PTP genes

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21) interaction partners

  1. PTPD1 is a component of a multivalent scaffold complex nucleated by FAK (show PTK2 Proteins) at specific intracellular sites

PTPN21 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.

Gene names and symbols associated with PTPN21

  • protein tyrosine phosphatase, non-receptor type 21 (PTPN21)
  • protein tyrosine phosphatase, non-receptor type 21 (Ptpn21)
  • Ptp2E protein
  • PTPD1 protein
  • PTPRL10 protein

Protein level used designations for PTPN21

dJ1175B15.2 (protein tyrosine phosphatase, non-receptor type 21) , protein tyrosine phosphatase D1 , protein-tyrosine phosphatase D1 , tyrosine-protein phosphatase non-receptor type 21 , protein-tyrosine phosphatase PTP-RL10 , protein tyrosine phosphatase 2E , protein-tyrosine phosphatase 2E

GENE ID SPECIES
11099 Homo sapiens
24000 Mus musculus
171070 Rattus norvegicus
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