You are viewing an incomplete version of our website. Please click to reload the website as full version.

Protein tyrosine Phosphatase Type IVA, Member 2 Proteins (PTP4A2)

The protein encoded by PTP4A2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping Protein tyrosine Phosphatase Type IVA, Member 2 Antibodies (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTP4A2 19244 O70274
PTP4A2 85237 Q6P9X4
PTP4A2 8073 Q12974
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Protein tyrosine Phosphatase Type IVA, Member 2 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,374.17
Details
HOST_Escherichia coli (E. coli) Human GST tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 4 to 6 Days
$385.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PTP4A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

Top referenced Protein tyrosine Phosphatase Type IVA, Member 2 Proteins

  1. Human PTP4A2 Protein expressed in Escherichia coli (E. coli) - ABIN2181677 : Cates, Michael, Stayrook, Harvey, Burke, Randall, Crowell, Crowell: Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases. in Cancer letters 1997 (PubMed)
    Show all 3 references for ABIN2181677

  2. Human PTP4A2 Protein expressed in Escherichia coli (E. coli) - ABIN667818 : Si, Zeng, Ng, Hong, Pallen: Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN667818

More Proteins for Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Interaction Partners

Mouse (Murine) Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) interaction partners

  1. Oncogenic PRL-2 controls tumor growth by modulating intracellular magnesium levels through binding with the CNNM3 (show CNNM3 Proteins) magnesium transporter.

  2. PTP4A2 plays critical roles in regulating hematopoietic stem cell self-renewal and mediating SCF (show KITLG Proteins)/KIT signaling.

  3. PRL2 promotes Kit-mediated PI3K/Akt signaling by reducing the level of PTEN that normally antagonizes the pathway.

  4. Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt (show AKT1 Proteins) protein

Human Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) interaction partners

  1. Our findings highlight the important role of miR (show MLXIP Proteins)-29c in regulating CRC (show CALR Proteins) EMT (show ITK Proteins) via GSK-3b/b-catenin signaling by targeting GNA13 (show GNA13 Proteins) and PTP4A and provide new insights into the metastatic basis of colorectal cancer

  2. PTP4A2 expression is correlated with overall survival in progestin receptor-positive breast carcinomas.

  3. Results suggest that TRP32 maintains the reduced state of PRL (show PRL Proteins) and thus regulates the biological function of PRL (show PRL Proteins).

  4. Studies indicate that PRL-1 (show PLRG1 Proteins) and PRL-2 and PRL-3 are oncogenes and belong to the few phosphatases that lead to the development of cancer.

  5. Results suggest a model in which PRL-2 promotes cell migration and invasion through an ERK1/2-dependent signaling pathway.

  6. PRL-2 plays an important role in lung cancer and can be a biomarker of lung cancer, substituting for the function of other PRLs.

  7. Overexpression of the protein tyrosine phosphatase (show ACP1 Proteins) PRL-2 correlates with breast tumor formation and progression.

  8. Mouse pre-B-cells transfected with human PRL-2 had higher growth responses to Epo (show EPO Proteins) or IL-3 (show Il3 Proteins), shorter cell cycle, less Epo (show EPO Proteins) requirement for survival, more cell migration, less cell adhesion, change to an immature cell morphology, & more Bmi-1 (show BMI1 Proteins) expression.

  9. PRL-2 can promote cell adhesion and invasion activity of human hepatocellular carcinoma cells.

  10. PRL (show PRL Proteins) phosphatases increase cell proliferation by stimulating progression from G1 into S phase

Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Protein Profile

Protein Summary

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

Gene names and symbols associated with PTP4A2

  • protein tyrosine phosphatase type IVA, member 2 (ptp4a2)
  • protein tyrosine phosphatase 4a2 (ptp4a2)
  • protein tyrosine phosphatase type IVA, member 2 (PTP4A2)
  • protein tyrosine phosphatase 4a2 (Ptp4a2)
  • HH7-2 protein
  • HH13 protein
  • HU-PP-1 protein
  • MGC53390 protein
  • MGC80084 protein
  • MGC132077 protein
  • OV-1 protein
  • PRL-2 protein
  • PRL2 protein
  • ptp-IV1a protein
  • ptp-IV1b protein
  • PTP4A protein
  • ptp4a2 protein
  • PTPCAAX2 protein
  • wu:fc05f09 protein
  • wu:fi84b06 protein
  • zgc:101724 protein

Protein level used designations for PTP4A2

PRL-2 , fc05f09 , protein tyrosine phosphatase type IVA 2 , protein tyrosine phosphatase 4a2 , protein tyrosine phosphatase type IVA, member 2 , protein-tyrosine phosphatase 4a2 , protein-tyrosine phosphatase of regenerating liver 2 , PTP(CAAXII) , phosphatase of regenerating liver 2 , protein tyrosine phosphatase IVA , protein tyrosine phosphatase IVA2

GENE ID SPECIES
334483 Danio rerio
379932 Xenopus laevis
419649 Gallus gallus
443874 Xenopus laevis
454687 Pan troglodytes
549961 Xenopus (Silurana) tropicalis
609835 Canis lupus familiaris
19244 Mus musculus
85237 Rattus norvegicus
8073 Homo sapiens
Selected quality suppliers for Protein tyrosine Phosphatase Type IVA, Member 2 Proteins (PTP4A2)
Did you look for something else?