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human homolog plays a role in anti-apoptosis. Additionally we are shipping PTMA Kits (29) and PTMA Proteins (16) and many more products for this protein.
Showing 10 out of 88 products:
Human Polyclonal PTMA Primary Antibody for EIA, FACS - ABIN954324
Skopeliti, Iconomidou, Derhovanessian, Pawelec, Voelter, Kalbacher, Hamodrakas, Tsitsilonis: Prothymosin alpha immunoactive carboxyl-terminal peptide TKKQKTDEDD stimulates lymphocyte reactions, induces dendritic cell maturation and adopts a beta-sheet conformation in a sequence-specific manner. in Molecular immunology 2009
Show all 5 references for ABIN954324
Human Polyclonal PTMA Primary Antibody for EIA, IHC (fro) - ABIN191566
Zółtowska: Pathogenesis of breast carcinoma. Immunohistochemical study. in Archivum immunologiae et therapiae experimentalis 1997
These results demonstrate the clinical relevance of prothymosin alpha in regulating acetylation events during the pathogenesis of emphysema.
Only neurons possess the specific mechanisms required to release prothymosin-alpha following cerebral ischemic stress in vivo.
Regional distribution and cell type-specific subcellular localization of Prothymosin alpha in brain.
Thymosin alpha-1 could relieve radiation-induced acute and late pulmonary injuries.
observations suggest that Talpha1 can positively modulate the haematopoietic functions of normal murine bone marrow cells, in addition to its myelorestorative role in tumour-bearing mice showing suppressed myelopoiesis [thymosin alpha-1]
thymosin alpha 1, a naturally occurring thymic peptide, induces functional maturation and interleukin-12 production by fungus-pulsed DCs through the p38 mitogen-activated protein kinase (show MAPK14 Antibodies)/nuclear factor (NF)-kappaB (show NFKB1 Antibodies)-dependent pathway.
ProT (show SLC6A7 Antibodies) overexpression in the kidneys of homozygous transgenic mice induced a PKD (show PRKD1 Antibodies) phenotype, which included polycystic kidneys, elevated blood urea nitrogen (BUN), and lethality at about 10 days of age.
Keap1 (show KEAP1 Antibodies)-bound prothymosin alpha peptide possesses a hairpin conformation and binds to cytoplasmic repressor Keap1 (show KEAP1 Antibodies) at the bottom region of the beta-propeller domain; complex formation occurs as a consequence of their complementary electrostatic interactions.
The systemic administration of Prothymosin alpha switches ischemia-induced necrosis to apoptosis, which in turn is inhibited by neurotrophic factors upregulated by Prothymosin alpha and ischemia.
prothymosin-alpha-mediated nuclear import of INrf2 (show KEAP1 Antibodies)/Cul3 (show CUL3 Antibodies) Rbx1 complex leads to ubiquitination and degradation of Nrf2 (show NFE2L2 Antibodies) inside the nucleus presumably to regulate nuclear level of Nrf2 (show NFE2L2 Antibodies) and rapidly switch off the activation of Nrf2 (show NFE2L2 Antibodies) downstream gene expression.
PTMA is a potential novel therapeutic target for type 2 diabetes
disease-free survival and overall survival rates were significantly lower among colorectal cancer patients with PTMA- and TP53 (show TP53 Antibodies)-positive tumors
Data suggest that KEAP1 (kelch-like ECH-associated protein 1 (show KEAP1 Antibodies)) mutations (as those observed in lung cancer patients) affect conformation/folding/stability of KEAP1 (show KEAP1 Antibodies) and binding affinity for ligands PTMA and NRF2 (nuclear factor erythroid 2-like 2 (show NFE2L2 Antibodies)).
Data suggest that plasma thymosin-alpha1 (TA1 (show TAAR1 Antibodies)) and prothymosin-alpha (PTMA) level may be a biomarker for differentiating between renal cell carcinoma (show MOK Antibodies) (RCC (show XRCC1 Antibodies)) and urothelial carcinoma.
prothymosin-alpha expression is a determinant of disease progression in superficial bladder cancer
PTalpha (show PTCRA Antibodies) offers cardioprotection against ischemic injury by an Akt (show AKT1 Antibodies)-dependent mechanism.
The PTMA is one of miR-1 target genes which involve in miR-1 inducing apoptosis.
Findings suggest that the binding of prothymosin alpha (ProTalpha) and Neh2 (show NEIL2 Antibodies) to Keap1 (show KEAP1 Antibodies) occurs synergistically via preformed structural elements.
Nuclear PTMA may serve as prognostic marker in head and neck squamous cell carcinoma to determine the subset of patients that are likely to show recurrence of the disease.
human homolog plays a role in anti-apoptosis
, prothymosin, alpha (gene sequence 28)
, prothymosin alpha
, gene sequence 28
, prothymosin alpha protein